Bilateral adrenal bleeding during bevacizumab treatment for metastatic colon cancer

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: RAS-mutant; BRAF-wild type; microsatellite stable.

Metastatic Site: peritoneum; liver; lung

Despite multiple systemic and local treatments, his metastatic colon cancer progressed in the liver and peritoneum, and he died from disease progression in November 2018.

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Stage IV Colorectal Cancer: Lee's Survivor Story

Patient Info: Lee Jones, Male, 50s | Stage IV

Metastatic Site: Liver

As of February 2021, Lee reported no evidence of colon cancer since 2011 after treatment for Stage IV colon cancer with liver metastases, recurrence, chemotherapy, colon surgery, and liver surgery.

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Rectal cancer liver surgery in a woman with mitochondrial disease

Patient Info: Anonymized, Female | Stage IV

Metastatic Site: liver; lungs; para-aortic lymph nodes

Three months after rectal and liver surgery, CT showed multiple lung metastases and para-aortic lymph-node metastasis, and FOLFIRI chemotherapy was resumed.

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Rectal cancer that later spread to the vagina

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: vagina

The isolated vaginal metastasis was surgically removed and followed by another 12 cycles of chemotherapy.

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Perforated appendicitis after surgery for stage I rectal cancer

Patient Info: Anonymized, Male, 70+ | Stage I

He recovered well after appendicectomy, was doing well at the four-week review, and remained under intensive rectal-cancer follow-up with community stoma and wound-care support.

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Emergency Repair of a Long-Term Perineal Hernia After Rectal Cancer Surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: lungs

She lived with metastatic rectal cancer and received community palliative care after becoming too frail for further chemotherapy.

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Stage IV Colorectal Adenocarcinoma: Kyle's Survivor Story

Patient Info: Kyle, Under 40 | Stage IV

Kyle was 19 months NED and off treatment after Stage IV colon adenocarcinoma, following about 30 months of chemotherapy and targeted therapy.

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Stage IV Colorectal Cancer: Maria's Patient Story

Patient Info: Maria | Stage IV

Metastatic Site: lungs

After colorectal cancer spread to the lungs, completed 6 months of chemotherapy and is being monitored with CT scans every 3 months.

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Stage II Colorectal Adenocarcinoma: Laura's Survivor Story

Patient Info: Laura | Stage II

Laura was declared cancer-free in 2025 after 2 surgeries for Stage II rectal adenocarcinoma.

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Stage IV Colorectal Adenocarcinoma: Amanda's Patient Story

Patient Info: Amanda, Under 40 | Stage IV

She remains on ongoing treatment for Stage IV disease and describes the cancer as pretty stable while maintaining a good quality of life.

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Stage II Colorectal Cancer: Chad's Patient Story

Patient Info: Chad | Stage II

Chad was recovering from radiation and preparing for major colorectal surgery while managing anxiety about treatment and its effects.

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Metastatic Right-Sided Colon Cancer With an NRG1 Fusion

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: KRAS mutation; POMK-NRG1 fusion

Metastatic Site: liver|lungs

He had persistent metastatic disease after 16 months of afatinib and entered a phase I trial in January 2020.

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Colorectal Cancer: Angela's Survivor Story

Patient Info: Angela

Angela was declared cancer-free in March 2022 after surgery and 4 months of chemotherapy.

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Stage I Colorectal Cancer: Mel's Survivor Story

Patient Info: Mel | Stage I

Cancer-free after partial colectomy and continued recovery after choosing not to receive chemotherapy.

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Stage III Colorectal Cancer: Cleo's Survivor Story

Patient Info: Cleo | Stage III

Cleo completed active treatment and reports that she is in remission more than 3 years after her February 2021 diagnosis.

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Stage III Colorectal Cancer: Anna's Survivor Story

Patient Info: Anna | Stage III

Anna remains under surveillance with scans and colonoscopies and reports No Evidence of Disease.

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Colon Cancer With an MLH1 Deletion and Lynch Syndrome

Patient Info: Anonymized, Male, Under 40 | Stage III

Biomarkers: dMMR with loss of MLH1 and PMS2. Familial MLH1 c.1057_1060delGCTG frameshift deletion identified; its clinical significance had not previously been reported.

The colon cancer progressed rapidly despite postoperative and second-line therapy, and he died from multiple organ failure one week after pembrolizumab was started.

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Stage I Colorectal Cancer: Paul's Survivor Story

Patient Info: Paul | Stage I

Completed treatment and described the cancer as beaten, with the goal of continuing life without cancer.

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Colorectal Cancer: Percy's Survivor Story

Patient Info: Percy

Completed treatment and described the cancer as being in remission.

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Stage III Colorectal Cancer: Kenneth's Patient Story

Patient Info: Kenneth | Stage III

About 2 years after diagnosis, Kenneth was still undergoing treatment for Stage III colorectal cancer in late 2023.

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Stage III Colorectal Cancer: Hilmi's Patient Story

Patient Info: Hilmi | Stage III

Hilmi was still undergoing chemotherapy and remained focused on recovery while managing a stoma and treatment side effects.

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Nearly 5 years without rectal cancer recurrence when a lung nodule proved to be infection

Patient Info: Anonymized, Male, 60s

He remained without rectal-cancer recurrence for nearly 5 years after diagnosis. A new lung nodule found in 2020 was surgically biopsied and proved to be Pneumocystis infection rather than metastasis or a new lung cancer.

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Scurvy and Severe Bruising During Metastatic Colon Cancer Care

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: vagina|sacrum

She died one year after hospitalization for scurvy and Klebsiella bacteremia, following progressive malignancy, recurrent infections, and community palliative care.

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Colon Cancer Survivor: "I Didn't Think I Had Symptoms, Diagnosed Stage 3B" | Shelley's Story

Patient Info: Shelley Brown, Female | Stage III

As of October 2020, Shelley was in remission / no evidence of disease several years after Stage IIIB sigmoid colon cancer treatment, with ongoing surveillance by scans, CEA, and colonoscopy.

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