Targeted Therapy for Colorectal Cancer: 28 Real Stories

28 stories match colorectal cancer and targeted therapy. 27 of them mention chemotherapy.

  1. Stage IV Colorectal Cancer: Sydney’s Patient Story

    Stage 4 · bevacizumab · capecitabine

    Sydney Stoner had digestive issues for years before lower abdominal pain became debilitating. The pain shifted from occasional constipation to frequent heavy pain with constipation and diarrhea. She tried elimination diets and holistic doctors, but she knew…

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  2. Stage IV Colorectal Cancer: Helen’s Survivor Story

    Stage 4 · Chemotherapy · Liver Directed Therapy

    Helen D. was diagnosed with Stage IV rectal cancer after her doctor called with urgent news. The cancer had spread to her liver, where doctors identified 10 to 14 lesions, several close to major blood vessels. Her care team initially warned that she might…

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  3. Stage IV Colorectal Cancer: Ken’s Patient Story

    Stage 4 · Chemotherapy · colectomy

    Ken was 59 when Stage IV sigmoid colon cancer was found after years of intermittent bowel changes. He had loose stools, increasing bathroom frequency, and occasional blood, but no abdominal pain and no major appetite problems, so he kept hoping the symptoms…

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  4. Stage IV Colorectal Cancer: Helen’s Survivor Story

    Stage 4 · Chemotherapy · FOLFIRI

    Helen was 49 when symptoms that seemed like a urinary tract infection led to a Stage IV sigmoid colon cancer diagnosis. She had pelvic pressure, burning with urination, bowel changes, bloating, and low energy. After 3 rounds of antibiotics and 2 enemas that…

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  5. Stage IV Colorectal Cancer: Jim’s Patient Story

    Stage 4 · bevacizumab · Chemotherapy

    Jim was 43 and felt healthy when routine blood work changed everything. A physical for an insurance discount showed high liver enzymes, and repeat blood work stayed abnormal. An ultrasound found multiple liver masses, followed by a biopsy and CT scan. He was…

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  6. Stage IV Colorectal Cancer: Joe’s Patient Story

    Stage 4 · capecitabine · Chemotherapy

    Joe never had blood in his stool. His warning signs were fatigue, loss of appetite, feeling generally off, and then severe shoulder, back, stomach, and liver-area pain. Because he worked long hours in the restaurant industry, the fatigue was easy to explain…

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  7. Stage IV Colorectal Cancer: Alyssa’s Patient Story

    Stage 4 · Chemotherapy · FOLFIRI

    Alyssa Kelly was 38 and pregnant in early 2021 when abdominal discomfort, weight loss and a concerning ultrasound finding led to an MRI. The news came by phone: Stage IV colon cancer. The main tumor was the size of a softball and pressed on her uterus…

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  8. Stage IV HER2-Positive Colorectal Cancer: John’s Patient Story

    Stage 4 · HER2 Positive · Targeted Therapy

    John E. was 44 when he was given a two-year prognosis and told chemotherapy was his only treatment option. With a wife and two daughters, he wanted another perspective and sought care at Mayo Clinic. Biomarker testing was raised immediately as part of that…

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  9. Stage IV BRAF Colorectal Adenocarcinoma: Pio’s Patient Story

    Stage 4 · BRAF Mutation · Chemotherapy · oxaliplatin

    Pio was 54, originally from Italy and living in Hawaii for 35 years, when a mild ache near his liver led to a Stage IV colon cancer diagnosis. He was still surfing, windsurfing, swimming, and training, so the pain felt small: about 2 out of 10. During a…

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  10. Stage IV Colorectal Cancer: Starr’s Survivor Story

    Stage 4 · Chemotherapy · Surgery

    Starr was 45 when abdominal pain pushed her to seek care. A scan showed multiple masses in her liver, and a hospital biopsy confirmed cancer there that had started elsewhere. She was diagnosed with Stage IV metastatic colon cancer, with later discussions also…

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  11. Stage IV BRAF Colorectal Cancer: Jackson’s Patient Story

    Stage 4 · BRAF Mutation · Chemotherapy · colostomy

    Jackson was 27 when worsening fatigue, thinning stool, blood in his stool, severe stomach pain, and projectile vomiting led him to the ER. He was diagnosed on January 11, 2025 with Stage IV colon cancer, a complete bowel blockage, and more than 40 tumors in…

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  12. Stage IV Colorectal Cancer: Heather’s Patient Story

    Stage 4 · Chemotherapy · FOLFOX

    Heather Candrilli was 35 when severe bloating and later rectal bleeding led her to a gastroenterologist. An abdominal ultrasound found lesions throughout her liver, and colonoscopy later found the colon mass. She was diagnosed with Stage IV colon cancer in…

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  13. Stage IV Colorectal Cancer: Jennifer’s Survivor Story

    Stage 4 · Single Nthl1 Mutation · cetuximab · Chemotherapy

    Jennifer Trefzger was diagnosed with colon cancer at 23 in 2017 after years of symptoms and severe iron deficiency. A colonoscopy found a 5 cm tumor blocking her descending colon. She was initially told the cancer was Stage III, but later learned it had…

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  14. Stage IV HER2-Positive Colorectal Cancer: Emily’s Patient Story

    Stage 4 · HER2 Positive · Chemotherapy · Clinical Trial

    Emily King was 27 when stomach pain and blood in her stool led to an ER visit. A CT scan showed a large tumor in her transverse colon. Surgeons removed about 1 foot of colon and 23 lymph nodes; 13 nodes contained cancer. Her early recovery was complicated by…

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  15. Stage IV Colorectal Adenocarcinoma: Nick’s Patient Story

    Stage 4 · bevacizumab · capecitabine

    Nick Sprague, a firefighter and critical care paramedic, was diagnosed with colorectal adenocarcinoma at age 48 after 1 to 2 years of bowel changes, blood in the stool, abdominal pain, reflux-like symptoms, and fatigue. An emergency visit first led to a…

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  16. Stage IV Colorectal Cancer: Steve’s Survivor Story

    Stage 4 · Chemotherapy · FOLFIRI

    Steve Slack was diagnosed with Stage IV colorectal cancer at age 48 after 2 years of bowel symptoms, including blood in the stool, changing bowel habits, bloating, gas-like pain, and abdominal pain. A colonoscopy on June 18, 2021, found a large tumor that…

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  17. Stage IV Colorectal Cancer: Jessica’s Survivor Story

    Stage 4 · Exact Mutation · Ablation · bevacizumab

    Jessica Dazzler was diagnosed with Stage IV colorectal cancer in January 2021, soon after her 37th birthday. For about 1 year before diagnosis, she had pelvic and tailbone pain, changing bowel habits, blood in the stool, low iron, and fertility-related…

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  18. Stage IV Colorectal Cancer Patient Story

    Stage 4 · Biomarker Testing · Chemotherapy

    Elsa Lankford became a caregiver when her wife was diagnosed with Stage IV colon cancer at age 49. The recommended screening age had been lowered from 50 to 45 only 2 months earlier. They already feared cancer, and the diagnosis was confirmed while Elsa’s…

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  19. Stage III Colorectal Cancer: Jena’s Patient Story

    Stage 3 · Biomarker Testing · Chemotherapy

    Jena Sica was 25 when rectal bleeding and fatigue led to a colonoscopy and a diagnosis of Stage IIIC colon cancer in 2020. Her care included biomarker testing, chemotherapy, targeted therapy or immunotherapy, and surgery. Jena used her experience to emphasize…

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  20. Stage IV Colorectal Cancer: Jason’s Patient Story

    Stage 4 · bevacizumab · Chemotherapy

    Jason Reese was 49 when he described living with Stage IV colorectal cancer that started in the rectum and spread extensively to his liver. For a long time, he explained away gastrointestinal distress as diet-related. Blood on the toilet paper slowly worsened…

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  21. Stage IV Colorectal Cancer: Keith’s Patient Story

    Stage 4 · bevacizumab · Chemotherapy

    Keith was 41 when abdominal pain after gallbladder removal led to an emergency room visit in May 2021. A CT scan showed a mass or blockage in his colon. Further evaluation also found affected lymph nodes and 4 lesions in his liver. He had emergency surgery…

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  22. Stage IV HER2-Positive Colorectal Cancer: Brian’s Patient Story

    Stage 4 · HER2 Positive · Chemotherapy · Clinical Trial

    Brian Beck was 54 when a positive at-home stool screening test led to colonoscopy and the discovery of a tumor in his sigmoid colon. Follow-up scans showed that the cancer had spread to his liver, making it Stage IV. Brian first had colon surgery to remove…

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  23. Stage IV Colorectal Cancer: Michelle’s Patient Story

    Stage 4 · bevacizumab · Chemotherapy

    Michelle Cappel was first diagnosed with Stage IV colorectal cancer in 2017. Initial treatment included chemotherapy and curative-intent surgery, and she reached no evidence of disease for about 2.5 years. As she approached the 3-year mark, she developed a…

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  24. Stage IV Colorectal Cancer: Jason’s Survivor Story

    Stage 4 · Chemotherapy · colostomy

    Jason Randall was diagnosed with Stage IV sigmoid colon cancer on July 17, 2018, after severe abdominal pain and bowel obstruction symptoms led to imaging. About 80% of his liver was covered with metastatic disease, and his sigmoid colon was fully blocked, so…

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