Stage III Colorectal Cancer: Nick's Survivor Story

Patient Info: Nick Cleworth, Male, 40s | Stage III

Cancer-free after ARTEMIS clinical-trial treatment for node-positive rectal cancer, avoiding surgery and a permanent colostomy.

The Christie NHSRead more →

Colorectal Cancer: Hatta's Survivor Story

Patient Info: Hatta, Male

No recurrence reported after interventional therapy, biological immunotherapy, Chinese medicine, and local radiotherapy for rectal cancer; later CT report was described as showing no cancer cells, with 8 years of normal life and annual checks.

Stage IV Colorectal Cancer: Antonio's Patient Story

Patient Info: Antonio, Male, 40s | Stage IV

Metastatic Site: Liver

Improved significantly after cryotherapy, interventional therapy, and bio-immunotherapy for Stage IV sigmoid colon cancer with liver metastasis; no NED/remission statement is reported.

Stage IV MSI-High Colorectal Cancer: Cindy's Patient Story

Patient Info: Cindy Mette, Female | Stage IV

Biomarkers: MSI-high

Cindy’s tumor responded to the experimental Werner helicase inhibitor, with falling CEA levels and radiologic response. The response was continuing in 2025 while she remained on the clinical trial.

MD AndersonRead more →

Stage III MSI-High Colorectal Adenocarcinoma: Briana's Survivor Story

Patient Info: Briana Ghbein, Under 40 | Stage III

Biomarkers: MSH2 mutation, dMMR/MSI-H

Postoperative pathology after her 2024 treatment showed no evidence of disease.

Fight Colorectal CancerRead more →

Stage IV MSI-High Colorectal Cancer: JJ's Patient Story

Patient Info: JJ, Male, Under 40 | Stage IV

Biomarkers: Lynch syndrome; microsatellite instability

Metastatic Site: Abdominal wall; lymph nodes throughout the body

At the latest scan, the main abdominal tumor remained stable. JJ had completed 126 rounds of chemo-immunotherapy and continued treatment every 3 weeks; small lung nodules were being watched but were not confirmed as metastases.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Jackie's Patient Story

Patient Info: Jackie, Female | Stage IV

Biomarkers: Lynch syndrome

Metastatic Site: Not reported

Jackie’s Stage IIIB rectal cancer later recurred as Stage IV/metastatic disease, but early immunotherapy response was strong, with no visible tumor on MD Anderson sigmoid scope about 6 weeks after starting treatment.

The Patient StoryRead more →

Stage I Colorectal Cancer: Hugo's Patient Story

Patient Info: Hugo, Male, Under 40 | Stage I

As of June 2026, Hugo had no active cancer after subtotal colectomy, but care remained ongoing with infusions every 6-8 weeks for bowel inflammation and high recurrence risk.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Joe's Patient Story

Patient Info: Joe, Male | Stage IV

Biomarkers: Specific biomarkers not reported

Metastatic Site: Liver; lymph nodes; lungs

Stage IV colon cancer initially reached no evidence of disease after FOLFOX plus panitumumab, but later recurred in the liver and lymph nodes, progressed to the lungs, and did not respond to later FOLFOX rechallenge or FOLFIRI before he started an immunotherapy clinical trial.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Cora's Patient Story

Patient Info: Cora, Female | Stage IV

Metastatic Site: Liver; lungs

As of February 2026, Cora had recurrent Stage IV colorectal cancer with a positive ctDNA test but clear CT imaging after stopping an immunotherapy trial because of toxicity, so ongoing care and monitoring were still needed.

The Patient StoryRead more →

Stage IV MSI-H KRAS-mutant colorectal adenocarcinoma: severe pembrolizumab-associated hypercalcemia resolved with steroids and zoledronic acid

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: KRAS G12xa mutation; MSI-H; BRAF wild type; NRAS wild type; PTH low-normal

Metastatic Site: liver

After the second pembrolizumab dose, severe hypercalcemia and electrolyte abnormalities resolved with high-dose glucocorticoids, zoledronic acid, and supportive care; cancer response was not yet described.

PubMed CentralRead more →

Stage III MSI-High Colorectal Cancer: Tommy's Survivor Story

Patient Info: Tommy Allen, Male, 50s | Stage III

Biomarkers: MSI-high; Lynch syndrome

As of November 2025, Tommy was cancer-free 5 years after pembrolizumab, ileostomy, Whipple procedure, partial colectomy, and ileostomy closure for Stage III MSI-high colon cancer with Lynch syndrome.

MD AndersonRead more →

Stage I Colorectal Cancer: Jessica's Survivor Story

Patient Info: Jessica, Female, Under 40 | Stage I

Biomarkers: Lynch syndrome

Jessica had Stage I Lynch syndrome-associated rectal cancer treated with an immunotherapy clinical-trial approach rather than chemoradiation or surgery. Midpoint colonoscopy and MRI showed the mass was gone, and she completed 7 infusions over 6 months. As of September 2025, she was in survivorship with intensive Lynch syndrome surveillance.

The Patient StoryRead more →

Colorectal Cancer: Shiva's Survivor Story

Patient Info: Shiva Sharma, Male, 40s

As of September 2025, Shiva described being told he was cancer-free after surgery and continued follow-up with scans every 6 months and regular colonoscopy.

The Patient StoryRead more →

MSI-H locally advanced right colon cancer: pathologic complete response after oxaliplatin, capecitabine, and immunotherapy

Patient Info: Anonymized, Female, 60s

Biomarkers: MSI-H on tumor gene testing

After oxaliplatin, capecitabine, and sindilizumab conversion therapy followed by laparoscopic radical right hemicolectomy, postoperative pathology showed no viable tumor cells and tumor regression grade 0 complete response.

PubMed CentralRead more →

Stage IV Colorectal Cancer: Esteban's Survivor Story

Patient Info: Esteban Moreno | Stage IV

Biomarkers: Lynch syndrome

After immunotherapy and surgery for Stage IV colorectal cancer, Esteban reported recent scans showing no signs of cancer and described himself as NED.

Fight Colorectal CancerRead more →

Lynch syndrome bifocal colon cancer: complete pathological remission after sintilimab

Patient Info: Anonymized, Male, 40s | Stage III

Biomarkers: Lynch-associated colon cancer with MSI-H and KRAS/NRAS/BRAF wild type; tumor markers were low or near normal.

As of April 2025, pathology after proximal colectomy showed tumor regression grade 0 with complete pathological remission, and follow-up found no recurrence or metastasis.

PubMed CentralRead more →

Shannin: Stage IV Colorectal Cancer

Patient Info: Shannin, Female, Under 40 | Stage IV

Biomarkers: Tumor-marker testing used to select immunotherapy

Metastatic Site: Liver

As of March 2025, Shannin was living with Stage IV colon cancer with cancer remaining in the liver while receiving chemotherapy and tumor-marker-matched immunotherapy.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Shannin's Patient Story

Patient Info: Shannin, Female, Under 40 | Stage IV

Biomarkers: Genetic testing negative; tumor-marker match for immunotherapy reported, exact marker not stated

Metastatic Site: liver; ovaries; peritoneum

Shannin has palliative Stage IV metastatic colorectal cancer with liver, ovarian, and peritoneal involvement. As of March 2025, she was continuing chemotherapy plus immunotherapy, had responded enough to keep treatment going, but still needed liver-directed options and did not qualify for a Canadian liver-pump trial.

The Patient StoryRead more →

Tamara: Stage IV Colorectal Cancer

Patient Info: Tamara, Female, 50s | Stage IV

Biomarkers: APC mutation; familial adenomatous polyposis

Metastatic Site: Liver | Lungs

As of March 2025, Tamara was living with Stage IV FAP-associated colon cancer involving the liver and lungs after completing 12 cycles of chemotherapy and immunotherapy.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Tamara's Patient Story

Patient Info: Tamara, Female, 50s | Stage IV

Biomarkers: FAP / APC mutation; reported de novo APC mutation

Metastatic Site: liver; lungs; retroperitoneal area reported initially

Tamara has Stage IV FAP/APC-associated colon cancer with liver and lung metastases. After chemotherapy plus immunotherapy, her numbers dropped sharply, lung disease cleared, and liver disease shrank but remained active; as of March 2025, she was continuing maintenance treatment.

The Patient StoryRead more →

Metastatic MSI-H colon cancer reaches pathologic complete response after immunotherapy and bevacizumab

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: KRAS, MSI-H

Metastatic Site: liver

The resected liver lesions showed pathologic complete response, and the last CT/MRI in November 2023 showed no recurrence or metastasis, more than 5 years after diagnosis.

PubMed CentralRead more →

Stage III MSI-H/dMMR ascending colon cancer: complete response to pembrolizumab without surgery

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: dMMR/MSI-H with high TMB, BRAF, BRCA2 mutation, KRAS/NRAS wild-type, HER2-negative, PD-L1-negative; Lynch testing negative.

After 10 months of pembrolizumab, PET/CT showed complete metabolic response and colonoscopy biopsies were negative for malignancy; she continued nonoperative management after declining surgery.

PubMed CentralRead more →

Stage IV Colorectal Adenocarcinoma: Casandra's Patient Story

Patient Info: Casandra, Female, Under 40 | Stage IV

Metastatic Site: Liver, lungs

As of November 2024, Casandra had been diagnosed just over a month earlier and was receiving aggressive every-2-week systemic therapy with the goal of shrinking disease enough to create surgical options.

The Patient StoryRead more →