Gastric Adenocarcinoma That Looked Like a Submucosal Tumor

Patient Info: Anonymized, male, 60s

The tumor was completely resected with clear margins, and follow-up CT and upper endoscopy were planned after surgery.

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Stage IV Gastric Cancer Responds to Nivolumab Before Severe Immune Hepatitis

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: HER2 1+; PD-L1 tumor-cell score 5%; mismatch-repair proteins intact; p53 mutated

Metastatic Site: liver

After an initial reduction in the gastric tumor and liver metastases, nivolumab was stopped for severe hepatitis and later disease progression with multi-organ failure was documented.

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Early Stomach Cancer Removed Endoscopically With No Recurrence 8 Years Later

Patient Info: Anonymized, Male, 70+

Eight years after endoscopic treatment for early gastric cancer, upper and lower endoscopy, imaging, and tumor-marker testing showed no evidence of recurrence or another malignancy.

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Early Papillary Stomach Cancer Found During Evaluation of Kidney Disease

Patient Info: Anonymized, Male, 70+

Biomarkers: THSD7A positive in intestinal-type adenocarcinoma; MUC2 positive; CDX2 positive

The gastric tumor was completely removed by distal gastrectomy, and the associated nephrotic syndrome improved within 3 months without immunosuppressive treatment.

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Aggressive SMARCA4-deficient gastric cancer with rapid liver metastases after surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: SMARCA4 loss; SMARCA4 frameshift mutation

Metastatic Site: liver

Multiple liver metastases appeared within 1 week after surgery. She received 1 chemotherapy cycle but could not continue because of poor condition and was transferred for hospice care.

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SMARCA4-deficient gastric cancer treated with surgery and adjuvant chemotherapy

Patient Info: Anonymized, Male, 70+

Biomarkers: SMARCA4 loss

After surgery and 5 cycles of adjuvant XELOX, he remained under surveillance without recurrence at the latest follow-up.

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Stage I Gastric Cancer: Sarah's Survivor Story

Patient Info: Sarah Grace Beckham, Under 40 | Stage I

Biomarkers: CDH1 mutation

Five years after the gastrectomy, the patient reported remaining cancer-free and living a normal, active life.

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Stage IV Gastric Cancer: Mark's Patient Story

Patient Info: Mark Scragg, male, Under 40 | Stage IV

Biomarkers: Lynch syndrome

After 3 months of chemotherapy and immunotherapy, scans showed no sign of the stomach tumor. By the 2025 article, Mark had finished active treatment, felt well, and his cancer was described as remaining largely in remission.

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Gastric cancer recurring in the rectum about 20 months after gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum, peritoneum

Metastatic gastric adenocarcinoma involved the rectum and pericolonic fat, with peritoneal nodules seen at surgery. He died 6 months after the rectal operation.

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Gastric cancer recurring in the rectum 7 months after total gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum

Rectal metastasis developed 7 months after gastrectomy. He entered hospice-led end-of-life care and died 2 months after the metastatic rectal diagnosis.

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A broken chemotherapy port catheter in a man with recurrent gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Metastatic Site: peritoneum

The gastric cancer progressed after recurrence, and he died two months after surgery to remove a broken chemotherapy-port catheter.

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Stage IV gastric cancer complicated by a fractured gastric outlet stent

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: peritoneum

He died while receiving palliative care 10 months after emergency surgery for a fractured-stent complication.

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Stage II Gastric Cancer: Irasema's Survivor Story

Patient Info: Irasema Partida Chavez, Female, Under 40 | Stage II

Irasema reported no evidence of stomach cancer for about 8 years after treatment for her localized recurrence.

Severe delayed bleeding after surgery for gastric cancer

Patient Info: Anonymized, female, 60s

Biomarkers: HER2-negative

At 1-year follow-up, she had no recurrent surgical-site bleeding and chemotherapy was initiated.

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Metastatic gastric cancer with Krukenberg tumors complicated by emergency bleeding

Patient Info: Anonymized, female, 60s | Stage IV

Metastatic Site: bilateral ovaries/adnexa (Krukenberg tumors)

She recovered well from emergency surgery for bleeding from a torsed Krukenberg tumor and was attending regular oncology follow-up 6 months later.

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Hereditary diffuse gastric cancer found after a small signet-ring cell tumor

Patient Info: Anonymized, male, 40s

Biomarkers: Pathogenic germline CDH1 frameshift mutation

Two years after total gastrectomy, he was alive and doing well without recurrence.

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HER2-Positive Metastatic Stomach Cancer Presenting With Tumor Lysis Syndrome

Patient Info: Anonymized, Male | Stage Metastatic/Advanced

Biomarkers: HER2 positive

Metastatic Site: liver

His metastatic gastric cancer progressed despite FOLFOX6 and trastuzumab. He entered hospice about 1 year later and died a few months afterward.

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Metastatic gastric cancer with an ATM mutation responding to olaparib

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: Pathogenic germline ATM mutation, HER2-negative, PD-L1 15%

Metastatic Site: peritoneum

He had a deep response lasting about 18 months, but imaging in December 2023 again showed peritoneal carcinomatosis.

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Mixed gastric neuroendocrine tumor and fundic-gland adenocarcinoma in autoimmune gastritis

Patient Info: Anonymized

No residual tumor was found in the gastrectomy specimen, and subsequent follow-up found no recurrence or metastasis.

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Metastatic gastric neuroendocrine carcinoma treated with repeated chemotherapy and immunotherapy

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, pancreas

More than 3 years after diagnosis, he remained in good condition on fifth-line treatment. April 2023 CT showed shrinkage of liver and pancreatic-tail metastases.

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Small signet-ring gastric cancer found during screening without H. pylori infection

Patient Info: Anonymized, female

Two years after endoscopic resection, periodic endoscopy and CT showed no local or metastatic recurrence.

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Gastric Cancer Treatment Interrupted by Capecitabine-Related Brain Toxicity

Patient Info: Anonymized, Female | Stage II

Her cognition and vital signs improved over several days after capecitabine was stopped. At follow-up 2 weeks later, chemotherapy remained suspended and the treatment plan was revised to radiation alone.

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Gastric cancer arising in hereditary juvenile polyposis

Patient Info: Anonymized, female, 70+

Biomarkers: Pathogenic germline SMAD4 splice-site variant

After total gastrectomy, her anemia and low protein levels improved, and no recurrence or metastasis had been reported.

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Nutritional recovery years after total gastrectomy for gastric cancer

Patient Info: Anonymized, male, 50s

He was alive 6 years after gastrectomy. PET in 2018 showed no recurrence, and CT in 2019 found no abdominal pathological changes while his later care focused on nutritional recovery.

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