Stage 4 Gastric Cancer: 107 Real Stories

107 stories match gastric cancer and stage 4. 88 of them mention chemotherapy.

A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Durable complete remission after brain metastases from gastric cancer

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: HER2-low, PD-L1 CPS 5

Metastatic Site: brain

By July 2024 the brain lesions had completely resolved, and complete remission remained sustained through October 2025, with more than 38 months off anticancer treatment.

PubMed Central
OutcomeCancer-Free / NED
Derek, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Stage IV Gastric Cancer: Derek's Patient Story

Patient Info: Derek Cooney | Stage IV

After a Stage IV stomach cancer diagnosis, an emergency physician sought several second opinions and enrolled in a clinical trial at UT MD Anderson.

MD Anderson
OutcomeNot reported
Derek, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV Gastric Adenocarcinoma: Derek's Survivor Story

Patient Info: Derek Cooney, Male, 40s | Stage IV

Metastatic Site: peritoneum

At his first follow-up in June, scans showed no evidence of disease, and he later completed his pain-management fellowship.

MD Anderson
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Gastric cancer treatment during hemodialysis after liver recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver|peritoneum

The cancer progressed in the peritoneum despite treatment, and systemic therapy was stopped in August 2024 before transfer to hospice in October 2024.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Stage IV AFP-producing gastric cancer responds to chemotherapy and immunotherapy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative; pMMR; elevated AFP

Metastatic Site: liver|peritoneum

Imaging showed a sustained partial response, his AFP level returned to normal, and he continued maintenance serplulimab at the latest follow-up.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Severe skin reaction after immunotherapy for metastatic gastric cancer

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: pMMR; PD-L1 CPS ~10; HER2 1+

Metastatic Site: liver

He recovered from the severe treatment-related skin reaction and was discharged after 32 days, with sintilimab permanently discontinued.

PubMed Central
OutcomeLiving With Cancer
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV gastric cancer with benign breast hemangioma during ramucirumab therapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: Gastric cancer: HER2 negative, PD-L1 TPS >=5%

Metastatic Site: peritoneum; preaortic lymph nodes; omentum

After initial response to FOLFOX/nivolumab and temporary benefit from paclitaxel/ramucirumab and FOLFIRI, the gastric cancer progressed to massive ascites. Trifluridine/tipiracil was attempted, but she died from rapid disease progression.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric CancerGastric Cancer

ALK-Fusion Gastric Cancer Responds to Alectinib Before Progression

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: DCTN1–ALK fusion; ATM p.E1724*; CDK6 amplification; HER2 negative; mismatch-repair proteins intact; later KRAS amplification

Metastatic Site: bone

Alectinib produced a partial response for about 11.5 months, but the cancer later progressed systemically and she died from uncontrollable gastrointestinal bleeding.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV Gastric Cancer Responds to Nivolumab Before Severe Immune Hepatitis

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: HER2 1+; PD-L1 tumor-cell score 5%; mismatch-repair proteins intact; p53 mutated

Metastatic Site: liver

After an initial reduction in the gastric tumor and liver metastases, nivolumab was stopped for severe hepatitis and later disease progression with multi-organ failure was documented.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Aggressive SMARCA4-deficient gastric cancer with rapid liver metastases after surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: SMARCA4 loss; SMARCA4 frameshift mutation

Metastatic Site: liver

Multiple liver metastases appeared within 1 week after surgery. She received 1 chemotherapy cycle but could not continue because of poor condition and was transferred for hospice care.

PubMed Central
OutcomeSetback / Progression
Mark, who was diagnosed with Stage IV Gastric CancerGastric Cancer

Stage IV Gastric Cancer: Mark's Patient Story

Patient Info: Mark Scragg, male, Under 40 | Stage IV

Biomarkers: Lynch syndrome

After 3 months of chemotherapy and immunotherapy, scans showed no sign of the stomach tumor. By the 2025 article, Mark had finished active treatment, felt well, and his cancer was described as remaining largely in remission.

Dana-Farber
OutcomeResponding Well
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Gastric cancer recurring in the rectum about 20 months after gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum, peritoneum

Metastatic gastric adenocarcinoma involved the rectum and pericolonic fat, with peritoneal nodules seen at surgery. He died 6 months after the rectal operation.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Metastatic gastric cancer with an ATM mutation responding to olaparib

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: Pathogenic germline ATM mutation, HER2-negative, PD-L1 15%

Metastatic Site: peritoneum

He had a deep response lasting about 18 months, but imaging in December 2023 again showed peritoneal carcinomatosis.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV Stomach Cancer With Recurrent Bowel Obstruction and Severe Pain

Patient Info: Anonymized, Male | Stage IV

Metastatic Site: splenic flexure|perineal nodule

He remained on palliative treatment more than 6 months after the described admission and had 3 additional hospitalizations for recurrent partial small-bowel obstruction, all managed without surgery.

PubMed Central
OutcomeLiving With Cancer