Stage IV Gastric Adenocarcinoma: Derek's Survivor Story

Patient Info: Derek Cooney, Male, 40s | Stage IV

Metastatic Site: peritoneum

At his first follow-up in June, scans showed no evidence of disease, and he later completed his pain-management fellowship.

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Metastatic gastric cancer with an ATM mutation responding to olaparib

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: Pathogenic germline ATM mutation, HER2-negative, PD-L1 15%

Metastatic Site: peritoneum

He had a deep response lasting about 18 months, but imaging in December 2023 again showed peritoneal carcinomatosis.

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Long-term complete response to nivolumab after recurrent Stage IV gastric cancer

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: HER2-negative, PD-L1 CPS ≤1

Metastatic Site: peritoneum, distant lymph nodes

About 7 years after surgery and roughly 3 years after starting nivolumab, CT showed no recurrent nodules or enlarged lymph nodes. She remained on nivolumab with a complete clinical response, had regained weight and returned to work.

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Dural metastasis causing seizures after treatment for signet-ring gastric cancer

Patient Info: Anonymized, female, Under 40 | Stage IV

Metastatic Site: dura mater

She died 16 days after hospital admission for neurologic symptoms, roughly 8 months after the original gastric-cancer diagnosis, following rapid deterioration from diffuse dural metastatic disease.

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Gastric Cancer Metastasis to the Hand Treated With Radiation

Patient Info: Anonymized, Male, 50s | Stage Metastatic/Advanced

Metastatic Site: liver|adrenal glands|left hand bones

Radiation relieved the hand pain and swelling and restored movement. At 6 months, he remained alive and pain-free in the hand, while the underlying metastatic gastric cancer remained present.

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Stage IV gastric cancer with peritoneal metastases responds to combined chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: peritoneum

At last follow-up in January 2018, she was asymptomatic and examinations showed no evidence of disease.

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Stage IV signet-ring gastric cancer with peritoneal metastases treated with chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: peritoneum

Developed peritoneal recurrence 3 months after postoperative chemotherapy and was receiving second-line chemotherapy at follow-up.

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Stage IV gastric adenocarcinoma progresses despite multiple chemotherapy approaches for peritoneal metastases

Patient Info: Anonymized, Male, Under 40 | Stage IV

Metastatic Site: peritoneum

The cancer progressed during second-line treatment, and he died from tumor-related complications in April 2017, about 16 months after his December 2015 admission.

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Stage IV HER2-negative gastric adenocarcinoma complicated by acute arterial thrombosis during chemotherapy

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: HER2-negative

Metastatic Site: peritoneum, retroperitoneal lymph nodes

After recovering from acute arterial thrombosis, he restarted cancer treatment with docetaxel and remained well without further complications at the latest follow-up.

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Gastric adenocarcinoma spreads to the liver and esophageal mucosa

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: liver, esophageal mucosa

The metastatic disease progressed despite 3 cycles of second-line docetaxel plus cisplatin.

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