Gastric Cancer: Gretchen's Survivor Story

Patient Info: Gretchen Borzi, Female, 40s

Biomarkers: germline CDH1 mutation

The cancers were localized with no lymph-node spread, and Gretchen was considered cured after gastrectomy.

Gastric adenocarcinoma causes SIADH through ectopic ADH secretion

Patient Info: Anonymized, Male, 60s

Biomarkers: ADH-positive tumor cells

He died from gastric-cancer progression 1.6 years after diagnosis despite surgery and chemotherapy.

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AFP-producing gastric adenocarcinoma causes biliary obstruction without liver metastasis

Patient Info: Anonymized, Female, Under 40

Biomarkers: markedly elevated serum AFP

After further chemotherapy became impossible, she was discharged in stable condition to Saint Vincent Island for comfort-focused care.

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Gastric cancer recurs in the spermatic cord 7 years after treatment

Patient Info: Anonymized, Male, 40s | Stage IV

Metastatic Site: epididymis, spermatic cord

At 26 months after orchiectomy, he was doing well with no evidence of recurrence, more than 9 years after his original gastric-cancer surgery.

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Gastric cancer recurs in the spermatic cord after 6 years without recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: spermatic cord

At 20 months after orchiectomy, he was stable with no recurrence, more than 7 years after treatment of his original gastric cancer.

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Gastric adenocarcinoma recurs in the adrenal gland 6 years after gastrectomy

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: left adrenal gland

At 13 months after resection of the adrenal metastasis, imaging and tumor-marker follow-up found no evidence of recurrence, placing him more than 7 years beyond the original gastrectomy.

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Signet-ring gastric cancer with repeated recurrences and a late adrenal metastasis

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: left adrenal gland

At 12 months after resection of the adrenal metastasis, no definite recurrence was found, roughly 7 years after the original gastric-cancer surgery.

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Stage I gastric adenocarcinoma treated with endoscopic resection and additional laparoscopic gastrectomy in situs inversus

Patient Info: Anonymized, Male, 40s | Stage I

At 18 months after surgery, he was doing well without recurrent gastric cancer.

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Metastatic gastric adenocarcinoma presents with Wernicke encephalopathy in a 35-year-old man

Patient Info: Anonymized, Male, Under 40 | Stage IV

Metastatic Site: liver

A 35-year-old man with vomiting, malnutrition and acute neurologic symptoms was diagnosed with Stage IV gastric adenocarcinoma with liver metastases and Wernicke encephalopathy.

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The Loss of a Mother

Patient Info: Anonymized, Female | Stage IV

She died in February 2013 after living with Stage IV gastric cancer while her daughter cared for her through treatment.

Gastric Cancer: Sara's Patient Story

Patient Info: Sara Souto Strom, Female

After treatment, Sara returned to an active life and continued her work as a cancer researcher.

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Seven synchronous early gastric cancers with extensive lymph-node involvement in an 85-year-old man

Patient Info: Anonymized, Male, 70+

An 85-year-old man was found to have seven synchronous early gastric adenocarcinomas, with 28 of 48 removed lymph nodes containing metastases despite shallow primary-tumor invasion.

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Stage IV primary gastric choriocarcinoma reaches 9 years with no evidence of disease

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: liver, lungs

She remained alive with no evidence of disease for 9 years after radiofrequency ablation, more than 9 years after the original diagnosis.

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Early gastric cancer returns in bone after an 8-year disease-free interval

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: bone

After an 8-year disease-free interval, he developed bone metastasis, received chemotherapy, developed disseminated intravascular coagulopathy and died in August 2011, nearly 10 years after the original diagnosis.

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Woman lives 6 years with untreated gastric signet-ring cell adenocarcinoma

Patient Info: Anonymized, Female, 70+

Six years after diagnosis, she remained alive with good appetite and persistent gastric signet-ring cell adenocarcinoma on repeat biopsy after declining gastrectomy and receiving no cancer-directed treatment.

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Stage III signet-ring gastric cancer is diagnosed only after repeated negative biopsies

Patient Info: Anonymized, Male, 50s | Stage III

He was alive at the latest follow-up after surgery and 8 courses of XELOX chemotherapy.

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Stage II signet-ring gastric cancer is found after repeated negative biopsies in a 52-year-old woman

Patient Info: Anonymized, Female, 50s | Stage II

She was alive at the latest follow-up after surgery.

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Gastric adenocarcinoma spreads to the liver and esophageal mucosa

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: liver, esophageal mucosa

The metastatic disease progressed despite 3 cycles of second-line docetaxel plus cisplatin.

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Metastatic gastric adenocarcinoma presents with severe breathing problems in a 24-year-old man

Patient Info: Anonymized, Male, Under 40 | Stage IV

Metastatic Site: lungs, pleura, mediastinal lymph nodes, bone

After 2 months of chemotherapy, imaging showed a partial response in the stomach and metastatic sites, and his breathing symptoms resolved without further oxygen support.

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Gastric Cancer: Johanna's Patient Story

Patient Info: Johanna Chelcun, Female, Under 40

She gradually rebuilt her strength and ran a half-marathon about 10 months after surgery.

Gastric Cancer: Laura's Patient Story

Patient Info: Laura McFetridge Ayala, Female, Under 40

Biomarkers: CDH1 mutation

She was recovering after total gastrectomy and adapting to life without a stomach.

Gastric adenocarcinoma first presents with painful eye and orbital metastases

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: left uvea, orbit, sclera, optic nerve

He died 6 months later after treatment for metastatic gastric cancer.

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Omental infarction mimics cancer recurrence after surgery for early gastric cancer

Patient Info: Anonymized, Female, 60s

At 12 months after gastric surgery, follow-up imaging showed the postoperative omental lesion had decreased without treatment, supporting resolving omental infarction rather than peritoneal cancer spread.

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Omental infarction causes abdominal pain after laparoscopic-assisted gastric-cancer surgery

Patient Info: Anonymized, Female, 60s

Five months after the postoperative omental infarction, follow-up imaging showed the lesion had almost resolved and PET imaging showed no abnormal uptake.

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