Gastric cancer recurring in the rectum about 20 months after gastrectomy

This gastric cancer diagnosis at a glance

Stage at diagnosis
Stage IV
Subtype
Adenocarcinoma
Sex
Male
Spread to
rectum, peritoneum
Treatment
chemotherapy, surgery and palliative care
Outcome
In Memory

Treatment course, step by step

  1. Received 2 cycles of neoadjuvant chemotherapy, which was stopped because of side effects.
  2. Underwent subtotal gastrectomy with radical lymphadenectomy.
  3. About 20 months later, underwent defunctioning colostomy followed by ultra-low Hartmann's resection for symptomatic rectal metastatic disease.
  4. Did not receive further chemotherapy because of declining health.

What happened, in summary

A 65-year-old man was diagnosed in 2016 with adenocarcinoma in the gastric antrum. He started neoadjuvant chemotherapy, but treatment was stopped after two cycles because of side effects. He then underwent subtotal gastrectomy with radical lymph-node dissection. The resected cancer was poorly differentiated and had clear margins.

About 20 months after gastric surgery, he developed rectal pain and tenesmus. Imaging showed abnormal thickening in the rectum, but the first biopsy found only inflammation. Because symptoms persisted, a defunctioning colostomy was created and he later underwent an ultra-low Hartmann's procedure. Surgery revealed peritoneal nodules and an advanced fibrotic rectal lesion.

Pathology confirmed that the rectal and pericolonic tumor was metastatic gastric adenocarcinoma rather than a new colorectal cancer. He later had repeated admissions for small-bowel obstruction and was not well enough for further chemotherapy. He died six months after the rectal operation.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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