Hereditary diffuse gastric cancer with a CDH1 mutation and a separate gallbladder cancer

Patient Info: Anonymized, female, 60s | Stage I

Biomarkers: Pathogenic germline CDH1 mutation

A 67-year-old woman with multiple small signet-ring gastric cancers underwent total gastrectomy and was found to carry a pathogenic germline CDH1 mutation.

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Stage IV Gastric Adenocarcinoma: Derek's Survivor Story

Patient Info: Derek Cooney, Male, 40s | Stage IV

Metastatic Site: peritoneum

At his first follow-up in June, scans showed no evidence of disease, and he later completed his pain-management fellowship.

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Gastric cancer surgery after chemotherapy with careful preservation of a liver artery

Patient Info: Anonymized, Male, 50s

He recovered without surgical complications and was discharged in stable condition on postoperative day 9.

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Gastric cancer treatment during hemodialysis after liver recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver|peritoneum

The cancer progressed in the peritoneum despite treatment, and systemic therapy was stopped in August 2024 before transfer to hospice in October 2024.

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Gastric cancer surgery and adjuvant treatment followed by endocrine complications

Patient Info: Anonymized, Female, 40s

After cancer treatment, she was hospitalized with severe nutritional and endocrine complications and improved with hormone replacement and nutritional support.

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Cancer-free after gastric surgery before a spontaneous twin pregnancy

Patient Info: Anonymized, Female, Under 40

She was described as cancer-free after gastrectomy before conceiving twins in 2024.

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Hereditary diffuse gastric cancer managed with repeated endoscopic treatment and gastrectomy

Patient Info: Anonymized, Male, 40s

Biomarkers: CDH1 mutation

Two years after total gastrectomy, he remained free of recurrence.

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Severe vitamin B12 deficiency 8 years after gastrectomy for gastric cancer

Patient Info: Anonymized, Male, 40s

A 49-year-old man developed severe neurologic problems from vitamin B12 deficiency 8 years after total gastrectomy for gastric cancer.

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Complete response in Stage IV gastric cancer after chemotherapy, immunotherapy, and surgery

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative; MSS; PD-L1 high

Metastatic Site: liver

He achieved a complete pathologic response and remained free of recurrence for 3 years and 3 months after surgery.

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Recovery from severe liver injury during Stage III gastric cancer treatment

Patient Info: Anonymized, Male, 70+ | Stage III

At the last follow-up in August 2025, imaging showed no recurrence and his liver function remained normal.

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Gastric Adenocarcinoma That Looked Like a Submucosal Tumor

Patient Info: Anonymized, male, 60s

The tumor was completely resected with clear margins, and follow-up CT and upper endoscopy were planned after surgery.

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Aggressive SMARCA4-deficient gastric cancer with rapid liver metastases after surgery

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: SMARCA4 loss; SMARCA4 frameshift mutation

Metastatic Site: liver

Multiple liver metastases appeared within 1 week after surgery. She received 1 chemotherapy cycle but could not continue because of poor condition and was transferred for hospice care.

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SMARCA4-deficient gastric cancer treated with surgery and adjuvant chemotherapy

Patient Info: Anonymized, Male, 70+

Biomarkers: SMARCA4 loss

After surgery and 5 cycles of adjuvant XELOX, he remained under surveillance without recurrence at the latest follow-up.

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Stage I Gastric Cancer: Sarah's Survivor Story

Patient Info: Sarah Grace Beckham, Under 40 | Stage I

Biomarkers: CDH1 mutation

Five years after the gastrectomy, the patient reported remaining cancer-free and living a normal, active life.

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Gastric cancer recurring in the rectum about 20 months after gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum, peritoneum

Metastatic gastric adenocarcinoma involved the rectum and pericolonic fat, with peritoneal nodules seen at surgery. He died 6 months after the rectal operation.

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Gastric cancer recurring in the rectum 7 months after total gastrectomy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: rectum

Rectal metastasis developed 7 months after gastrectomy. He entered hospice-led end-of-life care and died 2 months after the metastatic rectal diagnosis.

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A broken chemotherapy port catheter in a man with recurrent gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Metastatic Site: peritoneum

The gastric cancer progressed after recurrence, and he died two months after surgery to remove a broken chemotherapy-port catheter.

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Stage II Gastric Cancer: Irasema's Survivor Story

Patient Info: Irasema Partida Chavez, Female, Under 40 | Stage II

Irasema reported no evidence of stomach cancer for about 8 years after treatment for her localized recurrence.

Severe delayed bleeding after surgery for gastric cancer

Patient Info: Anonymized, female, 60s

Biomarkers: HER2-negative

At 1-year follow-up, she had no recurrent surgical-site bleeding and chemotherapy was initiated.

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Hereditary diffuse gastric cancer found after a small signet-ring cell tumor

Patient Info: Anonymized, male, 40s

Biomarkers: Pathogenic germline CDH1 frameshift mutation

Two years after total gastrectomy, he was alive and doing well without recurrence.

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Mixed gastric neuroendocrine tumor and fundic-gland adenocarcinoma in autoimmune gastritis

Patient Info: Anonymized

No residual tumor was found in the gastrectomy specimen, and subsequent follow-up found no recurrence or metastasis.

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Metastatic gastric neuroendocrine carcinoma treated with repeated chemotherapy and immunotherapy

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, pancreas

More than 3 years after diagnosis, he remained in good condition on fifth-line treatment. April 2023 CT showed shrinkage of liver and pancreatic-tail metastases.

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Gastric Cancer Treatment Interrupted by Capecitabine-Related Brain Toxicity

Patient Info: Anonymized, Female | Stage II

Her cognition and vital signs improved over several days after capecitabine was stopped. At follow-up 2 weeks later, chemotherapy remained suspended and the treatment plan was revised to radiation alone.

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Gastric cancer arising in hereditary juvenile polyposis

Patient Info: Anonymized, female, 70+

Biomarkers: Pathogenic germline SMAD4 splice-site variant

After total gastrectomy, her anemia and low protein levels improved, and no recurrence or metastasis had been reported.

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