FOLFOX for Gastric Cancer: 10 Real Stories

Gastric cancer surgery after chemotherapy with careful preservation of a liver artery

Patient Info: Anonymized, Male, 50s

He recovered without surgical complications and was discharged in stable condition on postoperative day 9.

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Gastric cancer treatment during hemodialysis after liver recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver|peritoneum

The cancer progressed in the peritoneum despite treatment, and systemic therapy was stopped in August 2024 before transfer to hospice in October 2024.

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Stage IV AFP-producing gastric cancer responds to chemotherapy and immunotherapy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative; pMMR; elevated AFP

Metastatic Site: liver|peritoneum

Imaging showed a sustained partial response, his AFP level returned to normal, and he continued maintenance serplulimab at the latest follow-up.

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Stage IV gastric cancer with benign breast hemangioma during ramucirumab therapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: Gastric cancer: HER2 negative, PD-L1 TPS >=5%

Metastatic Site: peritoneum; preaortic lymph nodes; omentum

After initial response to FOLFOX/nivolumab and temporary benefit from paclitaxel/ramucirumab and FOLFIRI, the gastric cancer progressed to massive ascites. Trifluridine/tipiracil was attempted, but she died from rapid disease progression.

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Metastatic Gastric Cancer Treatment Complicated by Recurrent Cytokine Release Syndrome

Patient Info: Anonymized, female, 70+ | Stage IV

Metastatic Site: peritoneum, bone

She had a partial response after 6 cycles but later chose to stop chemotherapy because treatment toxicity and declining health were affecting quality of life.

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HER2-Positive Metastatic Stomach Cancer Presenting With Tumor Lysis Syndrome

Patient Info: Anonymized, Male | Stage Metastatic/Advanced

Biomarkers: HER2 positive

Metastatic Site: liver

His metastatic gastric cancer progressed despite FOLFOX6 and trastuzumab. He entered hospice about 1 year later and died a few months afterward.

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Metastatic gastric neuroendocrine carcinoma treated with repeated chemotherapy and immunotherapy

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, pancreas

More than 3 years after diagnosis, he remained in good condition on fifth-line treatment. April 2023 CT showed shrinkage of liver and pancreatic-tail metastases.

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Gastric cancer and a large abdominal aortic aneurysm treated in one operation

Patient Info: Anonymized, male, 50s | Stage III

At 1-year follow-up, CT and upper endoscopy showed no local or distant recurrence.

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Stage IV HER2-Positive Gastric Cancer: Bryan's Patient Story

Patient Info: Bryan Chagolla, Male, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Bryan had a strong response to trastuzumab deruxtecan in 2021. He died on May 13, 2022, surrounded by loved ones.

Gastric cancer with an unexpected appendix metastasis

Patient Info: Anonymized, female, 50s | Stage IV

Metastatic Site: appendix

PET/CT at 6, 12 and 18 months showed no recurrence, giving at least 18 months with no evidence of disease after treatment.

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