Early kidney injury after first-line treatment for lung adenocarcinoma

Patient Info: Anonymized, Male, 70+

Kidney function improved after a short prednisone course, and he later continued cancer care with carboplatin and nab-paclitaxel.

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Severe immune-related kidney and lung toxicity during treatment for lung adenocarcinoma

Patient Info: Anonymized, Male, 60s

Corticosteroid treatment returned kidney function to baseline, but worsening immune-related lung toxicity led him and his family to choose palliative care.

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Kidney inflammation during maintenance treatment for lung adenocarcinoma

Patient Info: Anonymized, Male, 50s

Kidney function remained stable during three months of follow-up after prednisone was started for biopsy-confirmed acute tubulointerstitial nephritis.

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Long-term erlotinib treatment alongside worsening kidney vasculitis

Patient Info: Anonymized, Male, 70+ | Stage IV

Metastatic Site: bone

Bone metastases showed osteosclerotic change after erlotinib began, and the drug continued because he was benefiting from treatment despite worsening renal vasculitis.

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An 8 mm Early Lung Adenocarcinoma Removed With Limited Lung Surgery

Patient Info: Anonymized, Male, 60s

The 8 mm lesion was removed, and final pathology showed minimally invasive adenocarcinoma, pT1a(mi).

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Stage IV Non-Small Cell Lung Cancer: Abby's Survivor Story

Patient Info: Abby Kanarek, Female, 60s | Stage IV

Biomarkers: PD-L1 90%

Metastatic Site: Brain

As of November 2021, Abby was in remission 2 years after only 4 Keytruda infusions, with the lung cancer eliminated and ongoing surveillance by a multidisciplinary City of Hope team.

City of HopeRead more →

Stage I Lung Cancer: Dave's Survivor Story

Patient Info: Dave Bjork, Male | Stage I

As of November 2021, Dave was a Stage I lung cancer survivor after surgery-only treatment, with no chemotherapy reported, and was active in lung cancer awareness advocacy.

The Patient StoryRead more →

Stage IV Lung Cancer: Anne's Patient Story

Patient Info: Anne LaPorte, Female | Stage IV

Biomarkers: Mutation identified by next-generation sequencing; specific mutation not reported

Metastatic Site: Spine; hips; lymph nodes; liver

As of November 2021, Anne was living with Stage IV lung cancer after oral treatment guided by tumor testing and later radiation, reporting a meaningful quality of life while advocating for self-advocacy and research.

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Stage I Lung Cancer: Bonnie's Survivor Story

Patient Info: Bonnie Ulrich, Female | Stage I

As of November 2021, Bonnie was described as in remission after Stage I lung cancer treated with surgery only, and as a 3-time lung cancer survivor active in anti-stigma advocacy.

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Stage IV Lung Cancer: Jeff's Patient Story

Patient Info: Jeff Meckstroth, Male | Stage IV

Biomarkers: Mutation identified by liquid biopsy; specific mutation not reported

Metastatic Site: Brain

As of November 2021, Jeff had lived more than 6 years after a Stage IV lung cancer diagnosis, with brain metastases cleared after an unnamed brain-penetrant therapy, while his cancer had progressed on multiple occasions.

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Stage III Lung Cancer: Heidi's Patient Story

Patient Info: Heidi Nafman-Onda, Female, 50s | Stage III

As of November 2021, this caregiver-focused segment centered on Heidi’s Stage IIIA lung cancer diagnosis and Pierre’s advocacy; treatment details and current disease response were not reported.

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Stage IV Lung Cancer: Keasha's Patient Story

Patient Info: Keasha Draft, Female, Under 40 | Stage IV

Keasha Draft died 1 month after marrying Chris Draft following a sudden Stage IV lung cancer diagnosis; the story is told to honor her and advance lung cancer awareness.

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Stage III Lung Adenocarcinoma: Heidi's Patient Story

Patient Info: Heidi Nafman-Onda, Female, 50s | Stage III

As of November 2021, Heidi was about 3 years out from a Stage IIIA adenocarcinoma lung cancer diagnosis and described living a high-quality life, but treatment details and remission/NED status were not reported.

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Stage IV Lung Cancer: Steve's Patient Story

Patient Info: Steve Castellaw, 70+ | Stage IV

Metastatic Site: right pelvis, L1 and L2 vertebrae, skull

After about 2 years on sotorasib, Steve had a large reduction in tumor size and his latest scans continued to look good while he returned to golf, exercise, and normal daily life.

Living with Cancer & My Survivorship : Lung Cancer

Patient Info: Ashley, Female, Under 40 | Stage IV

Biomarkers: EGFR-positive; T790M mutation

As of September 2021, Ashley was living with incurable but treatable EGFR-positive T790M non-small cell lung cancer and described 43 months on treatment/journey while using community support to sustain hope.

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Stage IV EGFR Lung Cancer: Ashley's Patient Story

Patient Info: Ashley, Female | Stage IV

Biomarkers: EGFR-positive; T790M-positive

Metastatic Site: Not reported

As of September 2021, Ashley was living with incurable but treatable EGFR-positive/T790M-positive lung cancer on daily osimertinib/Tagrisso with ongoing oncology monitoring and side-effect management.

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Cancer Survivor Story: How I Got Diagnosed with Lung Cancer

Patient Info: Ashley, Female, Under 40 | Stage IV

Biomarkers: EGFR-positive; T790M mutation

Metastatic Site: Both lungs

As of August 2021, Ashley had been living for almost 4 years with incurable but treatable EGFR-positive T790M non-small cell lung cancer involving many tiny nodules across both lungs.

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A 3D anatomical model helped guide right upper-lobe lung cancer surgery

Patient Info: Anonymized

The planned right upper-lobe resection was completed using the interactive model to identify pulmonary vessels and the bronchus during surgery.

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Non-Small Cell Lung Cancer: Susan's Survivor Story

Patient Info: Susan Taylor, Female, 70+

As of July 2021, Susan had localized non-small cell lung cancer removed by robotic left upper lobectomy with lymph node removal and had returned to normal activities within 3 weeks; no metastatic disease or systemic therapy was reported.

Cleveland ClinicRead more →

ECMO-Supported Airway Tumor Removal in Stage IIB Lung Cancer

Patient Info: Anonymized, Male, 50s | Stage II

He recovered from the emergency airway procedure and remained on systemic cancer treatment at the last follow-up.

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ECMO-Supported Airway Tumor Removal for Squamous Lung Cancer

Patient Info: Anonymized, Male, 60s

Bronchoscopy at three months found no malignancy, and he remained disease-free one year after hospital discharge.

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Stage I EGFR Lung Adenocarcinoma: Ashley's Patient Story

Patient Info: Ashley Stringer, Female, Under 40 | Stage I

Biomarkers: EGFR-positive

As of May 2021, Ashley was 4 years from diagnosis after lobectomy and 2 radiation courses, with ongoing monitoring of lung nodules and possible future EGFR-targeted therapy if needed.

MD AndersonRead more →

A small primary lung adenocarcinoma found during treatment for a separate gestational cancer

Patient Info: Anonymized, Female, 50s | Stage I

Biomarkers: TTF-1 positive; napsin A positive.

The 9 mm lung adenocarcinoma was removed with clear margins and described as curatively resected, with CT surveillance continuing every six months.

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Facial paralysis from progression of EGFR-positive metastatic lung cancer improved with osimertinib

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: EGFR exon 21 p.Leu858Arg mutation.

Metastatic Site: brain; leptomeninges and facial nerves

Osimertinib rapidly resolved the bilateral facial weakness and reduced the brain lesions, but after 15 months seizures recurred and three smaller brain metastases had increased in size.

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