Hereditary diffuse gastric cancer in a 34-year-old man with a CDH1 mutation

Patient Info: Anonymized, Male, Under 40 | Stage III

Biomarkers: CDH1 monoallelic deletion of exons 1-2

Under surveillance with the most recent CT showing no active disease and no evidence of disease at the latest follow-up.

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Microscopic gastric cancer found after preventive gastrectomy in a 32-year-old man with a CDH1 mutation

Patient Info: Anonymized, Male, Under 40

Biomarkers: CDH1 monoallelic deletion of exons 1-2

Recovered after a postoperative pancreatitis episode and was doing well without evidence of disease at the latest follow-up.

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Microscopic gastric cancer found after preventive gastrectomy in a 23-year-old woman with a CDH1 mutation

Patient Info: Anonymized, Female, Under 40

Biomarkers: CDH1 monoallelic deletion of exons 1-2

Continued follow-up with no evidence of disease at the latest follow-up.

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Gastric cancer surgery leads to the diagnosis of previously unrecognized Gaucher disease

Patient Info: Anonymized, Female, 60s

A 69-year-old woman underwent surgery for gastric adenocarcinoma, while unusual bone-marrow and lymph-node findings led to a separate diagnosis of Gaucher disease.

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Gastric cancer diagnosed after pregnancy-related symptoms and gastric perforation

Patient Info: Anonymized, Female, Under 40 | Stage IV

CT after chemotherapy showed a good response, but her condition later deteriorated with multiple thromboses associated with metastatic disease. She died a few months after diagnosis.

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Stage IV gastric cancer with peritoneal metastases responds to combined chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: peritoneum

At last follow-up in January 2018, she was asymptomatic and examinations showed no evidence of disease.

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Stage IV signet-ring gastric cancer with peritoneal metastases treated with chemotherapy, surgery and HIPEC

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: peritoneum

Developed peritoneal recurrence 3 months after postoperative chemotherapy and was receiving second-line chemotherapy at follow-up.

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Stage IV gastric adenocarcinoma progresses despite multiple chemotherapy approaches for peritoneal metastases

Patient Info: Anonymized, Male, Under 40 | Stage IV

Metastatic Site: peritoneum

The cancer progressed during second-line treatment, and he died from tumor-related complications in April 2017, about 16 months after his December 2015 admission.

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Stage IV signet-ring gastric cancer with peritoneal metastases treated with chemotherapy, gastrectomy and HIPEC

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: peritoneum

At follow-up, he had no signs of recurrence.

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Robotic gastric cancer surgery in a man with situs inversus totalis and no recurrence at 2.5 years

Patient Info: Anonymized, Male, 50s

Biomarkers: HER2 2+

At 2.5 years after surgery, there was no recurrence.

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Stage III Gastric Adenocarcinoma: Harrison's Survivor Story

Patient Info: Harrison | Stage III

Several years after diagnosis, Harrison described being in remission while continuing to fear that the gastric cancer could return.

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Stage II gastric adenocarcinoma diagnosed at the same time as Hodgkin lymphoma

Patient Info: Anonymized, Male, 40s | Stage II

Biomarkers: HER2 IHC 0

Routine follow-up was ongoing as of November 2016.

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Metastatic gastric cancer returns about 5 years after treatment and causes pulmonary tumor thrombotic microangiopathy

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: bone marrow; pulmonary microvasculature

He died of respiratory failure from pulmonary tumor thrombotic microangiopathy on hospital day 45, about 5 years after his initial gastric cancer diagnosis.

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Gastric Cancer: Do's Survivor Story

Patient Info: Do Lee, Male, 70+

He had shown no evidence of disease since October 2017.

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Metastatic gastric cancer recurs 12 years after gastrectomy and severe hypocalcemia follows denosumab

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: pleura

She died 68 days after receiving denosumab during progressive recurrent disease, roughly 12 years after her original gastric cancer surgery.

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Five Years Without Recurrence After Surgery and Gamma Knife for a Cerebellar Metastasis From EGJ Cancer

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: CK7 negative, CK20 positive

Metastatic Site: cerebellum

Five years after removal of the cerebellar metastasis and Gamma Knife radiosurgery, she was asymptomatic with no evidence of recurrence.

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Fundic-gland-type gastric adenocarcinoma treated by endoscopic resection in a man with multiple gastric cancers

Patient Info: Anonymized, Male, 50s

No residual fundic-gland-type adenocarcinoma was found around the endoscopic resection scar in the later gastrectomy specimen.

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Antral gastric adenocarcinoma treated with total gastrectomy in a man with multiple gastric cancers

Patient Info: Anonymized, Male, 50s

A 58-year-old man with a separate small fundic-gland-type tumor also had a larger antral gastric adenocarcinoma that required total gastrectomy.

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A small intramucosal gastric cancer found unexpectedly after total gastrectomy

Patient Info: Anonymized, Male, 50s

A third, previously unseen intramucosal gastric cancer was discovered in the gastrectomy specimen of a 58-year-old man already being treated for two other gastric tumors.

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Gastric cancer causes severe pulmonary hypertension that improves rapidly with imatinib

Patient Info: Anonymized, Female, 50s | Stage IV

She died from systemic metastatic gastric cancer 7 months after the pulmonary vascular presentation.

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Stage III gastric adenocarcinoma later spreads to the gingiva and responds to local treatment

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: HER2-negative

Metastatic Site: gingiva

The gingival metastasis disappeared after treatment, and the disease remained stable through March 2017.

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Gastric cancer surgery in a man recovering from anti-NMDA receptor encephalitis

Patient Info: Anonymized, Male, 50s

At 2 months after surgery, he was symptom-free and had no postoperative complications.

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Stage II gastric cancer develops a solitary splenic metastasis one year after surgery

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: spleen

He remained well with no evidence of recurrence for 18 months after splenectomy, roughly 2.5 years after the original gastrectomy.

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A man with locally invasive gastric adenocarcinoma develops liver necrosis after pancreaticoduodenectomy

Patient Info: Anonymized, Male, 60s

At 1 year after surgery, CT showed no cancer recurrence.

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