Robotic gastric cancer surgery in a man with situs inversus totalis and no recurrence at 2.5 years

A patient, who was diagnosed with Gastric Adenocarcinoma

This gastric cancer diagnosis at a glance

Subtype
Adenocarcinoma
Biomarkers
HER2 (C-erbB-2) 2+
Sex
Male
Treatment
chemotherapy and surgery
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Received 2 cycles of neoadjuvant oxaliplatin plus S-1 chemotherapy.
  2. Underwent robotic distal gastrectomy with D2 lymph-node dissection and Billroth II reconstruction.
  3. Received 4 postoperative cycles of the same chemotherapy.

What happened, in summary

A 53-year-old man was admitted in December 2014 with upper-abdominal bloating. CT showed thickening of the distal stomach and enlarged nearby lymph nodes. Imaging also confirmed situs inversus totalis, meaning his internal organs were arranged in a mirror-image pattern. Endoscopy found a 6-cm antral tumor, and biopsy showed gastric adenocarcinoma with a HER2 (C-erbB-2) score of 2+.

Because of the tumor size and enlarged lymph nodes, he received 2 cycles of preoperative oxaliplatin plus S-1 chemotherapy. In February 2015, he underwent fully robotic distal gastrectomy with D2 lymph-node dissection and Billroth II reconstruction. The surgical team adapted the port placement and dissection to his reversed anatomy. Pathology showed residual gastric adenocarcinoma involving the stomach wall, with 4 of 5 lymph nodes along the greater curvature involved.

He recovered quickly, was discharged on the fifth postoperative day, and began postoperative chemotherapy one week later. He completed 4 additional cycles of the same regimen. Two and a half years after surgery, no recurrence had developed.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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