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A 60-year-old man had been diagnosed with advanced gastric cancer in the antrum 14 months earlier. He underwent palliative subtotal gastrectomy with gastrojejunostomy to relieve gastric-outlet obstruction, and pathology confirmed adenocarcinoma.
During later follow-up, CT showed multiple liver metastases. He also developed difficulty swallowing. Endoscopy found a small polyp-like mass in the upper esophagus, while the remaining stomach showed no local recurrence. Biopsy of the esophageal lesion matched the gastric adenocarcinoma, confirming an unusual mucosal metastasis from the stomach cancer.
The combination of liver and esophageal spread established metastatic Stage IV disease. He was treated with second-line docetaxel plus cisplatin chemotherapy. After 3 cycles, however, the cancer continued to progress. This was an uncommon route of spread to the esophageal mucosa together with treatment-resistant metastatic gastric adenocarcinoma.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer