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A 50-year-old man developed recurrent upper-abdominal discomfort, reflux, hiccups and weight loss. Imaging repeatedly showed thickening of the gastric antrum, but several endoscopic biopsies found only inflammation or fibrous tissue. He was initially treated for gastritis, while a multidisciplinary team continued to suspect an infiltrative gastric cancer.
Over the following months he underwent repeated endoscopy, deeper sampling and additional imaging. The sixth gastroscopy biopsy finally identified signet-ring cell carcinoma in the gastric antrum. CT showed enlarged perigastric lymph nodes, and he proceeded to surgery.
He underwent radical distal gastrectomy with D2 lymph-node dissection. Final pathology showed poorly differentiated adenocarcinoma involving the full thickness of the gastric wall, with cancer in 12 of 27 lymph nodes. The cancer was Stage III, with 12 of 27 lymph nodes involved. Beginning 4 weeks after surgery, he received 8 courses of XELOX chemotherapy. He was alive at the latest follow-up.
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
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These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer