Stage III gastric sarcomatoid carcinoma treated with surgery and chemotherapy

Patient Info: Anonymized, female, 50s | Stage III

She was alive and healthy at telephone follow-up 3 years after surgery.

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Stage III gastric carcinosarcoma treated with surgery

Patient Info: Anonymized, male, 70+ | Stage III

He died 1 month after surgery from cachexia and asphyxia related to gastroesophageal reflux.

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Rapidly progressive AFP-producing gastric cancer with widespread metastases and severe blood-clotting complications

Patient Info: Anonymized, male, 50s | Stage IV

Biomarkers: AFP-positive

Metastatic Site: liver, lymph nodes, bone, muscle, subcutaneous tissue

He died shortly after presentation from a massive brain hemorrhage in the setting of disseminated intravascular coagulation, before systemic anticancer treatment could be started.

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Laparoscopic Surgery for Gastric Cancer in a Patient With Reversed Organ Anatomy

Patient Info: Anonymized, Male, 70+

The gastric cancer was completely removed, with clear lymph nodes and no distant metastases. He was well without recurrence at the 1-month follow-up.

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Ramucirumab and paclitaxel for metastatic gastric cancer in a patient receiving hemodialysis

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, distant lymph nodes

After about 16 months of disease control on paclitaxel plus ramucirumab, multiple liver metastases and distant lymph nodes progressed. Third-line irinotecan was stopped after severe toxicity, and supportive care followed.

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Gastric Cancer Presenting With Painful Skeletal Muscle Metastases

Patient Info: Anonymized, Male, 40s | Stage Metastatic/Advanced

Metastatic Site: skeletal muscles

He had painful skeletal muscle metastases, an ECOG performance score of 3, and advanced gastric cancer that was not suitable for tumor-directed treatment. His care focused on palliation and end-of-life support.

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Stage II Gastric Cancer: Mawar's Patient Story

Patient Info: Mawar, female | Stage II

Mawar chose to discontinue further treatment after surgery and chemotherapy and focused on family life while remaining concerned that the gastric cancer could worsen.

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Stage II Gastric Cancer: Miguel's Patient Story

Patient Info: Miguel | Stage II

Miguel had completed chemotherapy and surgery and continued recovering while managing dumping syndrome, malabsorption and nutritional needs.

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Stage II Gastric Cancer: Andy's Patient Story

Patient Info: Andy | Stage II

Andy was still undergoing treatment and reported that targeted therapy was the current treatment.

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Three small gastric cancers resembling gastritis in a patient without Helicobacter pylori infection

Patient Info: Anonymized, male, 60s

All three lesions were removed endoscopically.

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Synchronous signet-ring gastric cancer and renal-cell cancer treated in one operation

Patient Info: Anonymized, female, 60s

She remained under active monthly surveillance. CT imaging and laboratory testing showed no evidence of gastric-cancer relapse or distant metastases.

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Hemodialysis used to manage 5-FU toxicity during treatment of Stage IV gastric cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: para-aortic lymph nodes, meninges

After a partial response to 7 cycles of chemotherapy, carcinomatous meningitis developed. Treatment was stopped, best supportive care was started, and he died 2 months later.

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Sjögren syndrome during nivolumab treatment for HER2-positive metastatic gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver, lungs, adrenal gland

One year after nivolumab was stopped, the shrinkage of lung metastases was maintained and the adrenal metastasis remained unchanged, although severe dry-mouth symptoms from treatment-related Sjögren syndrome persisted.

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Dural metastasis causing seizures after treatment for signet-ring gastric cancer

Patient Info: Anonymized, female, Under 40 | Stage IV

Metastatic Site: dura mater

She died 16 days after hospital admission for neurologic symptoms, roughly 8 months after the original gastric-cancer diagnosis, following rapid deterioration from diffuse dural metastatic disease.

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Scirrhous gastric cancer discovered during surgery for an upside-down stomach

Patient Info: Anonymized, female, 70+

After hernia repair, severe nausea and malaise improved, but oral intake remained difficult because of tumor involvement near the lower esophagus. A central venous port was placed, and she was transferred to another medical hospital on postoperative day 52.

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MSI-High Gastric Cancer With a Complete Response to Preoperative Nivolumab

Patient Info: Anonymized, Female, 60s

Biomarkers: MSI-high; PD-L1 expression in more than 1% of tumor cells; HER2 negative

Surgery found a complete pathologic response with no residual tumor cells and no cancer in 12 lymph nodes. At the time of reporting, she had no complaints and had returned to normal activities.

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Five years recurrence-free after surgery for a solitary splenic metastasis from gastric cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: spleen

He remained well without recurrence for 5 years after splenectomy for the solitary gastric-cancer metastasis.

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Mixed adenocarcinoma and neuroendocrine gastric cancer found in the gastric remnant

Patient Info: Anonymized, male, 70+

At 1-year follow-up, endoscopy and CT showed no local recurrence or lymph-node metastasis.

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Gastric Cancer Spreading to the Thumb

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: right thumb distal phalanx

She had advanced gastric cancer with pancreatic involvement and a painful thumb bone metastasis. Her treatment remained palliative because she was too frail for chemotherapy.

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Primary Gastric Melanoma Removed With Total Gastrectomy

Patient Info: Anonymized, Male, 50s

Biomarkers: Melan-A positive; HMB45 positive

PET-CT at 6 months showed no recurrence, and he remained asymptomatic at 1 year. He continued surveillance every 6 months.

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Primary gastric squamous cell carcinoma mistaken for a submucosal tumor

Patient Info: Anonymized, male, 60s | Stage III

At 6 months after surgery, follow-up CT showed no metastatic disease. He had declined adjuvant chemotherapy.

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Gastric Cancer: Emily's Patient Story

Patient Info: Emily Aldrich, Under 40

Biomarkers: CDH1 mutation

After recovery, the patient returned to exercise, regained the 8 pounds lost after surgery and later became pregnant with a first child.

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Graves disease during nivolumab treatment for HER2-positive metastatic gastric cancer

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver, brain

After progression through several treatment lines and development of brain metastasis, he died 4 months after evaluation for nivolumab-associated Graves disease, more than 1.5 years after his Stage IV gastric-cancer diagnosis.

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Steroid treatment for severe narrowing after gastric cancer surgery

Patient Info: Anonymized, male, 70+

The postoperative anastomotic narrowing improved, and he required no dietary restrictions for 6 months after completing systemic steroid treatment.

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