Gastric Cancer: Dan's Patient Story

Patient Info: Dan Kane

Biomarkers: Hereditary gastric-cancer predisposition confirmed by genetic testing

About 10 months after surgery, Dan had returned to work, was eating broadly, and described a healthier lifestyle without additional cancer treatment.

Dan Kane: His Sister’s Gastric Cancer Journey

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Her gastric cancer returned after partial gastrectomy and had spread by the time she underwent total gastrectomy.

Gastric Cancer: Chad's Patient Story

Patient Info: Chad White, Male

Four years after surgery, Chad was active in physique competitions and building a fitness and nutrition business.

Stage IV Gastric Cancer: Ernie's Patient Story

Patient Info: Ernie Pierce, Male, 60s | Stage IV

He died on July 8, 2009, after living with Stage IV gastric cancer for about 15 months.

Mr. Knight

Patient Info: Mr. Knight, Male, 60s

About a month after completing 5 weeks of chemotherapy and radiation, he was beginning to improve but still faced a long recovery.

Gastric Cancer: Amy's Patient Story

Patient Info: Amy Marshall, Under 40

Amy was preparing for total gastrectomy after cancerous cells were found in the stomach.

Amy Marshall: Her Mother’s Stomach Cancer

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

She died in 2003 after a rapid course of stomach cancer that had already spread when diagnosed.

Gastric Cancer: Rosie's Patient Story

Patient Info: Rosie Rosanna Fiorino, Under 40

Rosie described herself as a stomach-cancer survivor and celebrated 17 years since total gastrectomy while continuing patient-support work.

Kidney Injury During Nivolumab Treatment for Stage IV Gastric Cancer

Patient Info: Anonymized, Male, 60s | Stage IV

Kidney function and proteinuria improved after nivolumab was stopped, but the gastric cancer progressed. Restarted nivolumab was ineffective, and treatment was changed to irinotecan.

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Kidney Disease During Treatment for Metastatic Gastric Cancer

Patient Info: Anonymized, Male, 70+ | Stage Metastatic/Advanced

Metastatic Site: liver

His condition worsened with nephrotic syndrome, malnutrition, treatment side effects, and progressing metastases. He died 5 months after the kidney biopsy following a fatal cerebral bleed.

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Stage IV HER2-Positive Gastric Cancer: Bryan's Patient Story

Patient Info: Bryan Chagolla, Male, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Bryan had a strong response to trastuzumab deruxtecan in 2021. He died on May 13, 2022, surrounded by loved ones.

Early gastric cancers treated endoscopically, followed by surgery for pyloric narrowing and hiatal hernia

Patient Info: Anonymized, male, 70+

One year after the corrective surgery, he had no reflux or passage-obstruction symptoms, and endoscopy showed good passage through the pylorus.

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Abdominal abscess after endoscopic removal of early gastric cancer

Patient Info: Anonymized, male, 70+

He recovered after surgical drainage of the post-ESD abscess and was discharged home 27 days after that admission.

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Large Type I Gastric Neuroendocrine Tumor Removed Endoscopically

Patient Info: Anonymized, Female, 60s

Biomarkers: Ki-67 less than 3%; hypergastrinemia

Endoscopy at 3 months showed no recurrent nodules, and she remained disease-free and symptom-free at 6 months.

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Stage IV gastric cancer treated with chemotherapy and hyperthermia in a patient with a vagus nerve stimulator

Patient Info: Anonymized, male, 50s | Stage IV

Metastatic Site: para-aortic lymph nodes, peritoneum

The gastric tumors and lymph-node disease initially shrank during treatment, but peritoneal dissemination developed. He died from progressive gastric cancer 8 months after treatment began.

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Gastric Cancer Forming a Fistula Into the Liver

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: liver|lungs

The cancer recurred locally with liver deposits 4 months after surgery and later spread to the liver and lungs. She declined further treatment, entered palliative care, and died in hospital about 2 months later.

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Rare gastric carcinosarcoma with AFP-producing hepatoid adenocarcinoma

Patient Info: Anonymized, female, 70+

Biomarkers: AFP-positive

She developed metastatic recurrence and died 8 months after gastrectomy.

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Stage IV gastric cancer with low platelets managed so chemotherapy could continue — Case 2

Patient Info: Anonymized, female, 70+ | Stage IV

After partial splenic embolization, her platelet count recovered and thrombocytopenia did not recur. She was receiving second-line ramucirumab plus paclitaxel at the latest follow-up.

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Stage IV gastric cancer with low platelets managed so chemotherapy could continue

Patient Info: Anonymized, female, 60s | Stage IV

Chemotherapy was able to continue after partial splenic embolization, but the gastric cancer later progressed and she died from the disease.

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Two early EBV-positive gastric cancers in one patient with H. pylori infection

Patient Info: Anonymized, male, 60s | Stage I

Biomarkers: EBV-positive

Three years after surgery, he was in good health with no recurrence or metastases.

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Stage IV gastric cancer with gastric outlet obstruction treated with a stent

Patient Info: Anonymized, female, 70+ | Stage IV

Metastatic Site: para-aortic lymph nodes

The second stent allowed her to continue eating solid food. She died from progressive gastric cancer 3 months after the repeat stent procedure.

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Locally invasive gastric cancer treated with chemotherapy followed by curative surgery

Patient Info: Anonymized, male, 70+ | Stage III

Biomarkers: HER2-negative

Six months after surgery, CT showed no recurrence.

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Metastatic Gastric Cancer Causing Severe Hormone-Related Complications

Patient Info: Anonymized, Male, 70+ | Stage Metastatic/Advanced

Biomarkers: HER2 negative; Ki-67 70%; CD56 positive; synaptophysin positive; weak chromogranin expression; ectopic ACTH secretion; elevated serum chromogranin A

Metastatic Site: liver

His liver metastases enlarged despite carboplatin, and his weight loss, appetite, and mobility worsened. He received palliative care during a later admission and died a few days afterward.

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Young man with hereditary diffuse gastric cancer and a CDH1 mutation

Patient Info: Anonymized, male, Under 40 | Stage IV

Biomarkers: CDH1 c.639G>A nonsense mutation, decreased E-cadherin expression

His health deteriorated rapidly and he died 4 months after the Stage IV diagnosis without receiving anticancer treatment.

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