Stage II KRAS Lung Adenocarcinoma: Roy's Survivor Story

Patient Info: Roy, Male, 50s | Stage II

Biomarkers: KRAS

As of May 2026, Roy described being cancer-free/in remission, back to flying professionally, and strong enough to complete his 5th marathon at the Boston Marathon.

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Lung cancer treated with tislelizumab: rare fluid buildup around the lung as a side effect

Patient Info: Anonymized, Male, 60s

After treatment of the bronchial-stump recurrence, the tumor remained stable. The delayed pleural effusion resolved within 10 days of methylprednisolone, and tumor stability continued for the next 15 months.

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Stage IV rectal mucinous adenocarcinoma with pancreatic metastasis: response to chemotherapy and staged surgery

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: CA 19-9 93.4 U/mL; CEA 3.4 ng/mL; pancreatic lesion biopsy consistent with colorectal origin

Metastatic Site: pancreas

As of May 2026, he had good clinical progress during 5 months of follow-up after staged treatment, including chemoradiation, FOLFOX, abdominoperineal resection, FOLFIRINOX, and Whipple resection of the pancreatic metastasis.

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Metastatic triple-negative breast cancer with orbital and bone metastases responding to nab-paclitaxel plus everolimus

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: Primary breast cancer was ER-low, PR/HER2 negative. Orbital metastasis was triple-negative with AKT1 exon 4 mutation.

Metastatic Site: right orbit/orbital mass; bone

At 6-month follow-up, systemic disease was stable, ocular symptoms had significantly improved, orbital metastases were stable on MRI, and the response was described as RECIST partial response/progression-free interval while treatment continued.

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Amy’s Stage 4 Hormone-Positive Lobular Breast Cancer Story

Patient Info: Amy, Female | Stage IV

Biomarkers: ER-positive; PR-positive; HER2-negative

Metastatic Site: Spine; pelvis

Amy was living with de novo stage 4 lobular breast cancer involving the spine and pelvis and remained active in rural-patient advocacy.

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Stage II Ovarian Squamous Cell Carcinoma: Caitlin's Survivor Story

Patient Info: Caitlin Koehler, female, Under 40 | Stage II

Biomarkers: PD-L1: high expression

After surgery for recurrence, Caitlin remained on maintenance therapy and her follow-up scans showed no evidence of disease.

MD AndersonRead more →

Stage IIB triple-negative metaplastic breast cancer with early metastatic recurrence: durable response to pembrolizumab-based therapy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Triple-negative metaplastic breast cancer with PD-L1 CPS 83.2, BRCA1/2 negative

Metastatic Site: lung, sternum

As of May 2026, she had more than 30 months of disease control after pembrolizumab-based therapy for early recurrent metastatic metaplastic breast cancer, with only mild residual sternal uptake and no disease progression.

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My Metastatic Breast Cancer Spread To My BRAIN!

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: brain

As of May 2026, the patient was living with metastatic breast cancer involving the brain, receiving 2 brain-directed chemotherapy infusions every 3 weeks, and describing the disease as chronic rather than a death sentence.

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Stage IV ALK Lung Cancer: Jake's Patient Story

Patient Info: Jake, Male, Under 40 | Stage IV

Biomarkers: ALK-positive mutation

Metastatic Site: brain; lung; ankle bone

As of May 2026, Jake was 28 and had lived more than 13 years with Stage IV ALK-positive lung cancer, with ongoing treatment history including targeted therapy, surgeries, radiation, clinical-trial therapy, and recent chemotherapy.

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Localized malignant phyllodes tumor of the breast: re-excision, radiation, and 24-month NED

Patient Info: Anonymized, Female, 40s

Biomarkers: Ki-67 20%; CD99-positive; Bcl2-positive; CD34-positive

Follow-up at 3, 6, 12, 18, and 24 months, including imaging and tumor-marker blood tests, showed no evidence of disease.

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More than 5 years of disease control with maintenance chemotherapy for Stage IV lung cancer

Patient Info: Anonymized, Male | Stage IV

Biomarkers: KRAS mutation; TP53 mutation

Metastatic Site: brain

After more than 60 months of follow-up and prolonged maintenance chemotherapy, the latest assessment found no evidence of current tumor progression.

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Stage IV Colorectal Cancer: Lawrence's Survivor Story

Patient Info: Lawrence Henry, Male, 50s | Stage IV

Metastatic Site: Lung; abdominal lymph nodes

As of May 2026, Lawrence had no evidence of disease on scans since November, no blood-test signs of recurrence, was off colon cancer treatment, and returned to UT MD Anderson every 3 months for checkups.

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I Lost My Wife To Metastatic Breast Cancer at 29 Years Old

Patient Info: Samantha, Female, Under 40 | Stage IV

Metastatic Site: rib/bone; lymph nodes; brain; liver

Samantha died from metastatic breast cancer in early January 2026 at age 29 after brain and liver progression, heart failure, and tumor lysis syndrome during her final hospitalization.

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Stage IV Ovarian Cancer First Found Through an Umbilical Metastasis

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: WT1-positive; CK7-positive; CA-125 321 U/mL at diagnosis

Metastatic Site: umbilicus

After 9 months of bevacizumab maintenance, her clinical and imaging findings remained stable.

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Eight years cancer-free after treatment for a rare ovarian Brenner tumor

Patient Info: Anonymized, Female, 50s | Stage I

Biomarkers: High Ki-67

At 8-year follow-up, surveillance showed no clinical or radiologic evidence of disease.

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Karen Coleman

Patient Info: Anonymized, Male

He died 21 days after his first symptom following septic shock, repeated surgeries, strokes and a heart attack, after life support was withdrawn.

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Stage IV BRCA Breast Cancer: Maralee's Survivor Story

Patient Info: Maralee, Female, Under 40 | Stage IV

Biomarkers: BRCA mutation

Metastatic Site: Brain

As of May 2026, Maralee had no evidence of active disease after prior Stage IV breast cancer with brain metastasis, had stopped the PARP inhibitor after 2 years, remained without brain recurrence long enough to pursue pregnancy, and gave birth to a second daughter.

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Durable response after multiple treatments for ovarian clear cell cancer

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: HRD-positive; BRCA-negative; ARID1A mutation; PD-L1 CPS 30

She achieved a complete response, completed maintenance immunotherapy in May 2024, and continued anlotinib with normal follow-up imaging and tumor markers.

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Stage III Colorectal Cancer: Kristen's Survivor Story

Patient Info: Kristen, Female | Stage III

Completed active treatment for Stage III colon cancer and entered survivorship while managing permanent chemotherapy-induced peripheral neuropathy and chronic pain.

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Gastric cancer surgery after chemotherapy with careful preservation of a liver artery

Patient Info: Anonymized, Male, 50s

He recovered without surgical complications and was discharged in stable condition on postoperative day 9.

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Stage III Non-Small Cell Lung Cancer: Susie's Survivor Story

Patient Info: Susie, Female | Stage III

As of May 2026, Susie described completed surgery, chemotherapy, and radiotherapy for Stage III non-small cell lung cancer and was advocating for smoke-free legislation; no NED status was stated.

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Stage ypT1aN0 triple-negative breast cancer with familial BRCA1 and OBSCN deletions

Patient Info: Anonymized, Female, Under 40

Biomarkers: Triple-negative breast cancer; HER2 1+/negative; Ki-67 20%+. Familial testing showed BRCA1 and OBSCN deletions.

She underwent modified radical mastectomy with sentinel lymph node dissection and continued postoperative follow-up, with the main clinical emphasis on familial BRCA1/OBSCN genetic susceptibility.

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Stage IV Colorectal Cancer: Nathan's Survivor Story

Patient Info: Nathan, Male, Under 40 | Stage IV

Metastatic Site: Liver; peritoneal membrane

Declared tumor-free after aggressive treatment for Stage IV colon cancer, including colectomy, FOLFOX chemotherapy, and HIPEC, while continuing to live with treatment effects, an ileostomy, neuropathy, and scan anxiety.

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Gastric cancer treatment during hemodialysis after liver recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver|peritoneum

The cancer progressed in the peritoneum despite treatment, and systemic therapy was stopped in August 2024 before transfer to hospice in October 2024.

PubMed CentralRead more →