Eight years cancer-free after treatment for a rare ovarian Brenner tumor

What happened, in summary

A 54-year-old woman was evaluated after reporting intermittent bleeding after menopause. Imaging found a 5.5 cm mass in the right ovary, with no evidence of distant spread. She underwent hysterectomy with removal of both ovaries and fallopian tubes.

Pathology confirmed a malignant Brenner tumor, a rare type of ovarian cancer. The tumor was classified as Stage I. It also had a high Ki-67 level, suggesting more active cell growth.

Because of the tumor’s aggressive features, her care team recommended additional chemotherapy after surgery. She completed 6 cycles of carboplatin and paclitaxel. Radiation was discussed but ultimately not given. Treatment was generally well tolerated, apart from mild peripheral neuropathy.

After chemotherapy, imaging showed no residual or recurrent cancer. She continued regular surveillance, and her tumor markers remained within the normal range. At the most recent follow-up, 8 years after treatment, there were still no clinical or radiologic signs of disease. Her long follow-up provides an encouraging outcome after treatment for this uncommon ovarian cancer.