Gastric cancer treatment during hemodialysis after liver recurrence
This gastric cancer diagnosis at a glance
- Stage at diagnosis
- Stage IV
- Subtype
- Adenocarcinoma
- Biomarkers
- HER2-negative
- Sex
- Male
- Spread to
- liver|peritoneum
- Treatment
- surgery, chemotherapy, immunotherapy and targeted therapy
- Outcome
- Setback / Progression
Treatment course, step by step
- He underwent distal gastrectomy for Stage I gastric cancer.
- After liver recurrence, he received nivolumab with FOLFOX while continuing hemodialysis.
- When peritoneal progression developed, treatment changed to ramucirumab plus albumin-bound paclitaxel.
- Systemic treatment was stopped because of severe fatigue and loss of appetite, and he later transferred to hospice.
What happened, in summary
A 65-year-old man receiving hemodialysis for kidney disease was diagnosed with gastric cancer in 2022. He underwent distal gastrectomy, and the cancer was initially classified as Stage I.
During surveillance in October 2023, imaging found 3 new lesions in the liver. A biopsy confirmed that these represented recurrent gastric cancer rather than his separate skin tumor. The recurrence made the gastric cancer Stage IV. Testing showed that the tumor was HER2-negative.
He began nivolumab together with FOLFOX chemotherapy while continuing regular hemodialysis. His treatment was adjusted several times because of fatigue, appetite loss, and blood-count changes. After 6 cycles, the liver lesions were stable or slightly smaller, but abdominal fluid increased and the clinical picture indicated progression in the peritoneum.
Treatment was changed to ramucirumab plus albumin-bound paclitaxel. He later found systemic treatment increasingly difficult because of severe fatigue and loss of appetite. Chemotherapy was stopped in August 2024, and he transferred to hospice in October 2024.
Where this story comes from
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
How we source and attribute stories Accuracy and limitations
Collections this story belongs to
- Stage 4 Gastric Cancer 72 stories
- Chemotherapy for Gastric Cancer 98 stories
These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer