Gastric Cancer: Daniel's Patient Story

Patient Info: Daniel ‘Joe’ Einspahr, Male

Biomarkers: BRAC2 mutation

Joe returned to full-time work and continued follow-up scans every 6 months after treatment for the local recurrence.

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Stage IV Gastric Adenocarcinoma: Doran's Patient Story

Patient Info: Doran Barro, Female, 70+ | Stage IV

Metastatic Site: peritoneum|liver|lungs

Doran entered hospice on September 24 and died on September 30, 2014, about 5 months after diagnosis.

Gastric Cancer: Sundar's Survivor Story

Patient Info: Sundar Matpadi, 40s

Sundar reported no evidence of disease after treatment, while continuing J-tube nutrition and gradually regaining weight.

Stage IV Gastric Cancer: Ernie's Patient Story

Patient Info: Ernie Pierce, Male, 60s | Stage IV

He died on July 8, 2009, after living with Stage IV gastric cancer for about 15 months.

Gastric Adenocarcinoma: Alan's Patient Story

Patient Info: Alan Gorman, 50s

Alan was receiving further chemotherapy after surgery because lymph nodes were involved.

Stage IV Gastric Cancer: Buddy's Patient Story

Patient Info: Buddy (Bernard), Male, 70+ | Stage IV

Metastatic Site: adrenal gland

Buddy died on November 9, 2012, a little more than 3 months after diagnosis.

Mr. Knight

Patient Info: Mr. Knight, Male, 60s

About a month after completing 5 weeks of chemotherapy and radiation, he was beginning to improve but still faced a long recovery.

Stage IV Gastric Cancer: Karen's Patient Story

Patient Info: Karen Lucas, Female, 60s | Stage IV

Karen died peacefully at home on January 30, 2014, at age 62, a little over 1 year after her Stage IV diagnosis.

Gastric Cancer: Rosie's Patient Story

Patient Info: Rosie Rosanna Fiorino, Under 40

Rosie described herself as a stomach-cancer survivor and celebrated 17 years since total gastrectomy while continuing patient-support work.

Kidney Injury During Nivolumab Treatment for Stage IV Gastric Cancer

Patient Info: Anonymized, Male, 60s | Stage IV

Kidney function and proteinuria improved after nivolumab was stopped, but the gastric cancer progressed. Restarted nivolumab was ineffective, and treatment was changed to irinotecan.

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Kidney Disease During Treatment for Metastatic Gastric Cancer

Patient Info: Anonymized, Male, 70+ | Stage Metastatic/Advanced

Metastatic Site: liver

His condition worsened with nephrotic syndrome, malnutrition, treatment side effects, and progressing metastases. He died 5 months after the kidney biopsy following a fatal cerebral bleed.

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Stage IV HER2-Positive Gastric Cancer: Bryan's Patient Story

Patient Info: Bryan Chagolla, Male, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

Bryan had a strong response to trastuzumab deruxtecan in 2021. He died on May 13, 2022, surrounded by loved ones.

Stage IV gastric cancer treated with chemotherapy and hyperthermia in a patient with a vagus nerve stimulator

Patient Info: Anonymized, male, 50s | Stage IV

Metastatic Site: para-aortic lymph nodes, peritoneum

The gastric tumors and lymph-node disease initially shrank during treatment, but peritoneal dissemination developed. He died from progressive gastric cancer 8 months after treatment began.

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Stage IV gastric cancer with low platelets managed so chemotherapy could continue

Patient Info: Anonymized, female, 60s | Stage IV

Chemotherapy was able to continue after partial splenic embolization, but the gastric cancer later progressed and she died from the disease.

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Stage IV gastric cancer with low platelets managed so chemotherapy could continue — Case 2

Patient Info: Anonymized, female, 70+ | Stage IV

After partial splenic embolization, her platelet count recovered and thrombocytopenia did not recur. She was receiving second-line ramucirumab plus paclitaxel at the latest follow-up.

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Stage IV gastric cancer with gastric outlet obstruction treated with a stent

Patient Info: Anonymized, female, 70+ | Stage IV

Metastatic Site: para-aortic lymph nodes

The second stent allowed her to continue eating solid food. She died from progressive gastric cancer 3 months after the repeat stent procedure.

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Locally invasive gastric cancer treated with chemotherapy followed by curative surgery

Patient Info: Anonymized, male, 70+ | Stage III

Biomarkers: HER2-negative

Six months after surgery, CT showed no recurrence.

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Metastatic Gastric Cancer Causing Severe Hormone-Related Complications

Patient Info: Anonymized, Male, 70+ | Stage Metastatic/Advanced

Biomarkers: HER2 negative; Ki-67 70%; CD56 positive; synaptophysin positive; weak chromogranin expression; ectopic ACTH secretion; elevated serum chromogranin A

Metastatic Site: liver

His liver metastases enlarged despite carboplatin, and his weight loss, appetite, and mobility worsened. He received palliative care during a later admission and died a few days afterward.

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Stage III gastric sarcomatoid carcinoma treated with surgery and chemotherapy

Patient Info: Anonymized, female, 50s | Stage III

She was alive and healthy at telephone follow-up 3 years after surgery.

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Ramucirumab and paclitaxel for metastatic gastric cancer in a patient receiving hemodialysis

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, distant lymph nodes

After about 16 months of disease control on paclitaxel plus ramucirumab, multiple liver metastases and distant lymph nodes progressed. Third-line irinotecan was stopped after severe toxicity, and supportive care followed.

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Stage II Gastric Cancer: Andy's Patient Story

Patient Info: Andy | Stage II

Andy was still undergoing treatment and reported that targeted therapy was the current treatment.

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Stage II Gastric Cancer: Mawar's Patient Story

Patient Info: Mawar, female | Stage II

Mawar chose to discontinue further treatment after surgery and chemotherapy and focused on family life while remaining concerned that the gastric cancer could worsen.

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Stage II Gastric Cancer: Miguel's Patient Story

Patient Info: Miguel | Stage II

Miguel had completed chemotherapy and surgery and continued recovering while managing dumping syndrome, malabsorption and nutritional needs.

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Hemodialysis used to manage 5-FU toxicity during treatment of Stage IV gastric cancer

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: para-aortic lymph nodes, meninges

After a partial response to 7 cycles of chemotherapy, carcinomatous meningitis developed. Treatment was stopped, best supportive care was started, and he died 2 months later.

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