Metastatic gastric cancer with Krukenberg tumors complicated by emergency bleeding

Patient Info: Anonymized, female, 60s | Stage IV

Metastatic Site: bilateral ovaries/adnexa (Krukenberg tumors)

She recovered well from emergency surgery for bleeding from a torsed Krukenberg tumor and was attending regular oncology follow-up 6 months later.

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HER2-Positive Metastatic Stomach Cancer Presenting With Tumor Lysis Syndrome

Patient Info: Anonymized, Male | Stage Metastatic/Advanced

Biomarkers: HER2 positive

Metastatic Site: liver

His metastatic gastric cancer progressed despite FOLFOX6 and trastuzumab. He entered hospice about 1 year later and died a few months afterward.

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Metastatic gastric cancer with an ATM mutation responding to olaparib

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: Pathogenic germline ATM mutation, HER2-negative, PD-L1 15%

Metastatic Site: peritoneum

He had a deep response lasting about 18 months, but imaging in December 2023 again showed peritoneal carcinomatosis.

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Metastatic gastric neuroendocrine carcinoma treated with repeated chemotherapy and immunotherapy

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver, pancreas

More than 3 years after diagnosis, he remained in good condition on fifth-line treatment. April 2023 CT showed shrinkage of liver and pancreatic-tail metastases.

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Gastric Cancer Treatment Interrupted by Capecitabine-Related Brain Toxicity

Patient Info: Anonymized, Female | Stage II

Her cognition and vital signs improved over several days after capecitabine was stopped. At follow-up 2 weeks later, chemotherapy remained suspended and the treatment plan was revised to radiation alone.

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Painful eye metastasis from Stage IV gastric cancer

Patient Info: Anonymized, male | Stage IV

Metastatic Site: bone, choroid of left eye

The eye surgery relieved his pain, but he died 2 months later.

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Gastric cancer and a large abdominal aortic aneurysm treated in one operation

Patient Info: Anonymized, male, 50s | Stage III

At 1-year follow-up, CT and upper endoscopy showed no local or distant recurrence.

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Localized Linitis Plastica With Gastric Amyloidosis Followed by Multiple Myeloma

Patient Info: Anonymized, Female

Biomarkers: CA19-9: 47.5 U/mL

She remained in clinical remission for 3 years after gastric cancer treatment, and later CT imaging showed no recurrent gastric disease when multiple myeloma was diagnosed.

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Adrenal metastasis from gastric cancer causing adrenal insufficiency

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-negative, PD-L1-negative

Metastatic Site: right adrenal gland

More than 17 months after the metastatic relapse, he was clinically well with no radiological or biochemical signs of active cancer apart from the residual right adrenal lesion.

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Solitary adrenal metastasis after surgery for gastric large-cell neuroendocrine carcinoma

Patient Info: Anonymized, male | Stage IV

Metastatic Site: right adrenal gland

Nine months after removal of the adrenal metastasis, he was alive and August 2022 CT showed no new metastases or tumor recurrence.

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Recurrent gastric cancer with bone metastases, venous thrombosis and chylothorax

Patient Info: Anonymized, male, 60s | Stage IV

Metastatic Site: bone

Biopsy-confirmed bone recurrence developed more than a year after surgery. He was too unwell for palliative chemotherapy and died a few months after transition to best supportive care.

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Stage IV gastric adenocarcinoma first detected through an appendiceal metastasis

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: appendix

He was referred to oncology for Stage IV gastric cancer and started capecitabine chemotherapy.

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Stage IV Gastric Adenocarcinoma: Angel's Survivor Story

Patient Info: Angel | Stage IV

Angel was declared cancer-free in August 2024 and described being NED within 1 year of the Stage IV gastric cancer diagnosis.

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Stage II Gastric Cancer: Sagan's Patient Story

Patient Info: Sagan | Stage II

Sagan reported completing cancer treatment and continued taking medicines for treatment-related symptoms while focusing on recovery.

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Recurrent gastric cancer with peritoneal spread and a difficult intestinal fistula

Patient Info: Anonymized, female, 70+ | Stage IV

Metastatic Site: peritoneum

About 10 years after her original gastrectomy, recurrent gastric cancer with peritoneal spread progressed despite palliative procedures. She died 3 months after her final reoperation.

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Synchronous gastric and pancreatic adenocarcinomas in a 76-year-old woman

Patient Info: Anonymized, female, 70+

Her health declined with repeated hospitalizations and failure to thrive. She could not tolerate treatment, transitioned to palliative care, and died shortly afterward.

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Gastric Cancer: Alan's Patient Story

Patient Info: Alan Salm, Male, 50s | Stage Metastatic/Advanced

Alan died from stomach cancer on May 5, 2021, 1 month before his 53rd birthday.

Stage IV gastric cancer with liver metastases cleared after chemotherapy, nivolumab and surgery

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: PD-L1-positive, HER2-negative

Metastatic Site: liver

After treatment cleared the gastric and liver lesions, all anticancer therapy was stopped. He remained relapse-free with no evidence of disease for 32 months.

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Stage IV gastric cancer with a TP53 blood finding traced to clonal hematopoiesis

Patient Info: Anonymized, male, 50s | Stage IV

Metastatic Site: distant lymph nodes

At age 57, 3 years 4 months after his Stage IV diagnosis, he remained alive after multiple lines of treatment; progression had occurred before his later-line regimens.

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Stage III signet-ring gastric cancer complicated by a life-threatening aortic fistula after treatment

Patient Info: Anonymized, male, 60s | Stage III

After staged repair of a life-threatening aortoesophageal fistula and later esophageal reconstruction, he was living independently and remained under follow-up without tumor recurrence.

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Metastatic hepatoid gastric adenocarcinoma achieving complete remission with sintilimab

Patient Info: Anonymized, male | Stage IV

Biomarkers: AFP markedly elevated

Metastatic Site: liver

By the fifth sintilimab cycle, gastroscopy showed no gastric tumor, CT showed no liver metastases and AFP had normalized; complete remission was confirmed and remained stable during subsequent treatment.

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HER2-positive metastatic gastric cancer responding to trastuzumab deruxtecan rechallenge

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver

After trastuzumab deruxtecan was restarted, his symptoms improved after the first cycle and imaging showed tumor shrinkage after 3 cycles. He was still receiving treatment without progression at the latest follow-up.

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Gastric adenocarcinoma diagnosed alongside a separate retroperitoneal liposarcoma

Patient Info: Anonymized, male

He died 3.5 months after admission from hepatorenal failure in the setting of severe jaundice caused by the rapidly progressive retroperitoneal liposarcoma. Autopsy showed gastric adenocarcinoma with regional lymph-node involvement but no distant organ metastasis from the gastric cancer.

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Long-term complete response to nivolumab after recurrent Stage IV gastric cancer

Patient Info: Anonymized, female, 70+ | Stage IV

Biomarkers: HER2-negative, PD-L1 CPS ≤1

Metastatic Site: peritoneum, distant lymph nodes

About 7 years after surgery and roughly 3 years after starting nivolumab, CT showed no recurrent nodules or enlarged lymph nodes. She remained on nivolumab with a complete clinical response, had regained weight and returned to work.

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