Nivolumab: 72 Real Stories

72 stories match nivolumab. 68 of them mention immunotherapy.

Cancer Stories

Becky, who was diagnosed with Stage III Lung AdenocarcinomaLung Cancer

Stage III Lung Adenocarcinoma: Becky's Survivor Story

Patient Info: Becky Manning, Female, 40s | Stage III

After surgery, chemotherapy and 8 months of nivolumab on a clinical trial, Becky was no longer on active treatment, had no evidence of disease, felt well, and returned to MSK every 6 months for follow-up.

Memorial Sloan Kettering
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Lung Squamous Cell CarcinomaLung Cancer

Stage IVA lung squamous cell carcinoma with immune-checkpoint-inhibitor-associated Graves thyroid storm

Patient Info: Anonymized, Male | Stage IV

Biomarkers: Cancer biomarkers not reported. Thyroid storm workup had TSAb/TRAb positivity consistent with Graves disease.

Metastatic Site: not specified in extracted case text

After thyroid storm improved with antithyroid therapy and supportive care, the patient was transferred for further lung-cancer treatment but died of progressive lung cancer about 2 months later.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Gastric cancer treatment during hemodialysis after liver recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative

Metastatic Site: liver|peritoneum

The cancer progressed in the peritoneum despite treatment, and systemic therapy was stopped in August 2024 before transfer to hospice in October 2024.

PubMed Central
OutcomeSetback / Progression
Ken, who was diagnosed with Stage IV MelanomaMelanoma

Stage IV Melanoma: Ken's Survivor Story

Patient Info: Ken Herich, Male, 60s | Stage IV

Metastatic Site: Abdomen; shinbone/bone; near lungs

After Stage IV melanoma progressed on prior immunotherapies, TIL therapy produced a complete response; as of April 2026, scans showed no evidence of disease and no sign of melanoma returning nearly 1 year after treatment.

City of Hope
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Stage IVB lung adenocarcinoma with severe immune-related complications

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: PD-L1 TPS 20%; BRAF mutation

Metastatic Site: left supraclavicular fossa, left axilla, right hilum,…

The patient had an initial partial response to ipilimumab/nivolumab but developed severe immune-related pneumonitis, thrombocytopenia, and aplastic anemia. Cytopenias recovered with eltrombopag, but lung cancer later relapsed with carcinomatous meningitis, and he died 20 months after diagnosis.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Lung Squamous Cell CarcinomaLung Cancer

Stage 4 lung cancer: large tumor managed with targeted care

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: PD-L1 TPS <1%

Metastatic Site: contralateral lymph nodes, supraclavicular lymph…

The patient had a partial response to CheckMate 9LA despite PD-L1 TPS <1%, later progressed after 24 cycles of immunotherapy, received additional chemotherapy, and died in November 20XX+2.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV gastric cancer with benign breast hemangioma during ramucirumab therapy

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: Gastric cancer: HER2 negative, PD-L1 TPS >=5%

Metastatic Site: peritoneum; preaortic lymph nodes; omentum

After initial response to FOLFOX/nivolumab and temporary benefit from paclitaxel/ramucirumab and FOLFIRI, the gastric cancer progressed to massive ascites. Trifluridine/tipiracil was attempted, but she died from rapid disease progression.

PubMed Central
OutcomeIn Memory
A patient, who was diagnosed with Metastasizing ameloblastoma involving lung Squamous Cell CarcinomaMetastasizing ameloblastoma involving lung

Metastasizing ameloblastoma involving lung: initially treated as squamous lung cancer

Patient Info: Anonymized, Male, 40s

Biomarkers: Final tumor had AKT1 mutation and BRAF -negative status. Initial testing found no common actionable lung-cancer drivers.

As of October 2025, final pathology had changed the diagnosis from suspected squamous lung cancer to metastasizing ameloblastoma involving the lung, and the patient was under specialist head-and-neck and thoracic follow-up.

PubMed Central
OutcomeCare Ongoing
A patient, who was diagnosed with Stage IV Gastric AdenocarcinomaGastric Cancer

Stage IV Gastric Cancer Responds to Nivolumab Before Severe Immune Hepatitis

Patient Info: Anonymized, male, 70+ | Stage IV

Biomarkers: HER2 1+; PD-L1 tumor-cell score 5%; mismatch-repair proteins intact; p53 mutated

Metastatic Site: liver

After an initial reduction in the gastric tumor and liver metastases, nivolumab was stopped for severe hepatitis and later disease progression with multi-organ failure was documented.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage III Lung AdenocarcinomaLung Cancer

Stage IIIA KRAS p.G12V lung adenocarcinoma: pathologic complete response after chemoimmunotherapy and surgery

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: KRAS p.G12V mutation; PD-L1 0% tumor-cell staining; <1% tumor-associated inflammatory-cell staining; no EGFR, ALK, or ROS1 driver mutation reported

Pathology after lobectomy showed a pathologic complete response, and surveillance imaging 12 months later showed no evidence of disease recurrence.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Non-Small Cell Lung CancerLung Cancer

Metastatic NSCLC with ATM mutations: 28-month response to olaparib before progression

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: cfDNA showed ATM and ATM mutations. Common NSCLC drivers were negative; initial tumor markers were negative.

Metastatic Site: liver, left pubic bone, bilateral pulmonary nodules,…

After 28 months of remission and improved quality of life on olaparib, June 2024 PET-CT showed progression with a new 1.2 cm hypermetabolic left lower-lobe pulmonary nodule; olaparib was still being continued at the October 2024 clinic visit.

PubMed Central
OutcomeSetback / Progression
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Metastatic lung adenocarcinoma: complete remission on nivolumab complicated by immune-mediated diabetes

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: Lung tumor: EGFR wild type, ALK rearrangement not detected. Immune-mediated diabetes: islet/GAD antibodies negative and C-peptide undetectable.

Metastatic Site: brain (cerebellum and occipital lobe); liver

As of March 2025, serial CT and MRI scans through October 2023 showed no evidence of oncologic disease after nivolumab, while immune-mediated diabetes was controlled with basal-bolus insulin.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Lung Squamous Cell CarcinomaLung Cancer

Stage IV Squamous Lung Cancer Complicated by an Esophageal-Mediastinal Fistula

Patient Info: Anonymized, male, 70+ | Stage IV

Metastatic Site: brain, bone

Four months after the fistula was treated conservatively, imaging showed the fistula had resolved and the lung tumor and metastatic hilar nodes had decreased despite no additional antitumor treatment during that interval.

PubMed Central
OutcomeResponding Well
A patient, who was diagnosed with Stage III Lung Squamous Cell CarcinomaLung Cancer

Stage 3 squamous cell lung cancer: major response to chemo-immunotherapy

Patient Info: Anonymized, Male, 70+ | Stage III

Biomarkers: PD-L1 30-40%

After neoadjuvant chemoimmunotherapy and sleeve right lower lobectomy, pathology showed major pathological response with negative margins, and no metastasis or recurrence was observed 6 months after surgery.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage II Lung Squamous Cell CarcinomaLung Cancer

Stage IIIA squamous lung cancer: surgery after nivolumab-related complications

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: PD-L1 TPS 99% before treatment; PD-L1 TPS 70% in postoperative hilar lymph node; TPOAb and TgAb normal during thyroiditis workup

As of January 2025, the patient had no recurrence 7 months after neoadjuvant nivolumab/carboplatin/paclitaxel and 5 months after thoracoscopic right upper lobectomy with lymph node dissection.

PubMed Central
OutcomeCancer-Free / NED
A patient, who was diagnosed with Lung Squamous Cell CarcinomaLung Cancer

Two Severe Kidney Injuries After Lung Cancer Immunotherapy

Patient Info: Anonymized, Male, 70+

The lung cancer remained stable without further anticancer treatment, while the patient remained dependent on hemodialysis after the second kidney injury and continued tapering prednisolone.

PubMed Central
OutcomeStable Disease / Care Ongoing
Sophie, who was diagnosed with Stage IV Colorectal CancerColorectal Cancer

Sophie: Stage IV Colorectal Cancer

Patient Info: Sophie, Female | Stage IV

Biomarkers: BRAF mutation; MSI

Metastatic Site: Liver; lymph nodes; other torso lesions

As of August 2024, Sophie had been declared cancer-free after Stage IV BRAF-mutated/MSI bowel cancer responded to nivolumab/ipilimumab-based immunotherapy, with PET imaging and liver surgery biopsy showing no cancerous cells.

The Patient Story
OutcomeCancer-Free / NED
A patient, who was diagnosed with Stage IV Lung AdenocarcinomaLung Cancer

Stage IV PD-L1-negative lung adenocarcinoma: complete response with nivolumab and ipilimumab

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: PD-L1-negative; no targetable molecular alterations on DNA/RNA next-generation sequencing; TP53 alteration reported at 66%

Metastatic Site: left pleural effusion; right adrenal gland;…

As of February 2024, she remained on maintenance nivolumab and ipilimumab after 14 cycles, without significant toxicity and with persistent complete response of Stage IV PD-L1-negative lung adenocarcinoma.

PubMed Central
OutcomeCancer-Free / NED