Stage IV BRCA1 Ovarian Cancer: Lauren's Patient Story

Patient Info: Lauren Corduck, Female | Stage IV

Biomarkers: BRCA1 mutation

Metastatic Site: lymph nodes, including a node near the left collarbone

Lauren was diagnosed with recurrent ovarian cancer in December 2017 and was undergoing chemotherapy, with a PARP inhibitor planned as the next treatment step.

Massachusetts General HospitalRead more →

Stage IV Ovarian Cancer: Manisha's Survivor Story

Patient Info: Manisha Koirala, Female | Stage IV

She was declared cancer-free after her final chemotherapy cycle on April 30, 2013, and remained in remission more than 6 years later.

Memorial Sloan KetteringRead more →

Rare ovarian cancer diagnosed during pregnancy after an initial misdiagnosis

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: SMARCA4 and TP53 alterations

Metastatic Site: liver|spleen|bone

After a complete response in July 2024, the cancer recurred widely within about 6 months. She died from progressive disease in January 2025.

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Targeted treatment for an 89-year-old woman with Stage IV HRD-positive ovarian cancer

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: HRD-positive; germline BRCA2 pathogenic variant

Follow-up imaging showed a partial response, tumor markers improved, and she remained on treatment with better appetite and general condition at 7 months.

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Stage IV Ovarian Cancer First Found Through an Umbilical Metastasis

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: WT1-positive; CK7-positive; CA-125 321 U/mL at diagnosis

Metastatic Site: umbilicus

After 9 months of bevacizumab maintenance, her clinical and imaging findings remained stable.

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Ovarian Cancer Metastatic to an Axillary Lymph Node Without Breast Disease

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: BRCA1/2 negative

Metastatic Site: right axillary lymph node

Secondary cytoreductive surgery in April 2025 achieved complete macroscopic cytoreduction, and she was discharged without complications.

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'How I knew I had ovarian cancer’: Survivors and caregiver discuss symptoms

Patient Info: Susan, female | Stage IV

Susan’s husband later shared her experience after her death, recalling the sudden abdominal swelling that preceded her Stage IV ovarian cancer diagnosis.

MD AndersonRead more →

Stage IV Ovarian Cancer: Evelyn's Survivor Story

Patient Info: Evelyn, female | Stage IV

Biomarkers: HRD-positive

After chemotherapy and surgery, Evelyn reported an unremarkable final scan in May 2023 and then completed 2 years of Lynparza maintenance therapy guided by HRD-positive tumor testing.

Ovarian cancer lung metastasis followed by a benign staple-line granuloma

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: lung

More than 10 years after her original ovarian-cancer surgery, a mass near the prior lung-metastasis staple line was surgically removed and proved to be a benign epithelial granuloma rather than recurrent cancer.

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Ovarian Cancer Spreads to the Breast During Platinum-Resistant Recurrence

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: BRCA1/2-negative; HRD-positive; PD-L1-positive; folate receptor alpha-positive

Metastatic Site: right breast, right axillary lymph nodes, cervical…

She remained alive with stable disease about 2 years after the breast metastasis was diagnosed while receiving seventh-line mirvetuximab-soravtansine.

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Stage IV Ovarian Cancer: Susan's Patient Story

Patient Info: Susan Dunwoody, female | Stage IV

Susan lived for 7 years after her Stage IV ovarian cancer diagnosis and later died from the disease.

MD AndersonRead more →

Stage IV Ovarian Cancer: Melbey's Patient Story

Patient Info: Melbey Segovia, Female | Stage IV

Melbey Segovia died on May 4, 2021, about 5 years and 3 months after her February 2016 diagnosis, after three relapses and hospice care.

Dana-FarberRead more →

Stage IV Ovarian Cancer Complicated by Anti-Yo Cerebellar Degeneration

Patient Info: Anonymized, Female | Stage IV

Biomarkers: CA-125: 1767 kU/L; anti-Yo antibodies positive in serum and cerebrospinal fluid

Her anti-Yo paraneoplastic cerebellar degeneration progressed despite methylprednisolone and plasma exchange. Care became palliative, and she died 2 months after hospital admission.

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Stage IV Ovarian Cancer: Carolyn's Patient Story

Patient Info: Carolyn Ridge, Under 40 | Stage IV

Carolyn was dealing with an ovarian cancer recurrence diagnosed in September 2014.

Dana-FarberRead more →

Stage IV ovarian cancer complicated by a spontaneous vaginal fistula

Patient Info: Anonymized, Female, 50s | Stage IV

After postoperative chemotherapy, she was clinically well and imaging showed no visible tumor during 8 months of follow-up.

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Stage 4 Ovarian Cancer Discovered During Trigeminal Neuralgia Evaluation

Patient Info: Anonymized, Female, 50s | Stage IV

Three months after surgery, she had recovered well from debulking and 6 total chemotherapy cycles, with complete macroscopic clearance achieved at surgery. Trigeminal-neuralgia symptoms persisted and continued to require daily medication.

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Kidney Complications After Treatment for Stage IV Ovarian Cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: peritoneum|left lymph node

No further ovarian-cancer progression was observed during the 10 months after kidney biopsy. The nephrotic syndrome reached partial remission after immunosuppressive treatment was stopped and supportive care continued.

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Ovarian cancer that later spread to an axillary lymph node

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: axillary lymph nodes

After later peritoneal progression, additional treatment brought the disease to a stable state through her last recorded visit in July 2019.

PubMed CentralRead more →

Ovarian cancer presenting with axillary lymph-node spread

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: axillary lymph nodes

A 39-year-old woman with high-grade serous ovarian cancer had confirmed spread to an axillary lymph node at diagnosis and underwent extensive cytoreductive surgery.

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Stage IV ovarian cancer with axillary lymph-node spread

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: axillary lymph nodes

A 58-year-old woman with ovarian serous carcinoma and axillary lymph-node spread received chemotherapy, cytoreductive surgery, and postoperative chemotherapy.

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Stage IV Ovarian Cancer With Severe Recurrent Ascites

Patient Info: Anonymized, Female | Stage IV

Metastatic Site: peritoneum|liver

The cancer progressed with massive ascites, liver involvement, and respiratory failure. She died from multiorgan failure related to metastatic ovarian cancer.

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Stage IV Ovarian Cancer: Janelle's Patient Story

Patient Info: Janelle Kister, female | Stage IV

Treatment ended, and Janelle was still doing well 17 years after her Stage IV ovarian cancer diagnosis.

MD AndersonRead more →

Stage IV ovarian cancer presenting as a persistent umbilical ulcer

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: bilateral cardiophrenic lymph nodes

She recovered from extensive cytoreductive surgery without major abdominal or pulmonary complications and began adjuvant paclitaxel and carboplatin on postoperative day 25.

PubMed CentralRead more →

Stage IV Ovarian Cancer With 20 Years of Tumor-Free Survival

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: BRCA1 negative, BRCA2 negative

Metastatic Site: peritoneum, liver, right adrenal gland

Regular follow-up found no recurrence or other tumor, and at 20 years of follow-up she remained tumor-free with good health and quality of life.

PubMed CentralRead more →