Stage IV BRCA1 Ovarian Cancer: Lauren's Patient Story
This ovarian cancer diagnosis at a glance
- Stage at diagnosis
- Stage IV
- Biomarkers
- BRCA1 mutation
- Sex
- Female
- Spread to
- lymph nodes, including a node near the left collarbone
- Treatment
- chemotherapy and surgery
- Outcome
- Setback / Progression
Treatment course, step by step
- In early 2017, Lauren received 35 hours of chemotherapy.
- She underwent surgery for Stage IV ovarian cancer.
- Her initial treatment ended on May 30, 2017.
- After ovarian cancer recurred in December 2017, she started chemotherapy again.
- A PARP inhibitor was planned afterward.
What happened, in summary
Lauren Corduck learned on December 31, 2016, that she carried a BRCA1 mutation inherited from her father. She had been preparing to consider risk-reducing surgery, but an MRI ordered for severe back pain revealed an unexpected finding. Further evaluation showed malignant lymph nodes caused by ovarian cancer, with spread through the lymph nodes to a node near her left collarbone. By the end of January 2017, she had been diagnosed with Stage IV ovarian cancer.
Lauren received 35 hours of chemotherapy and underwent surgery at Massachusetts General Hospital. Her initial treatment ended on May 30, 2017. She described the medical and emotional support from her care team as central to getting through treatment, and the experience also inspired her to build Oneinforty, a nonprofit focused on BRCA awareness among Ashkenazi Jewish families.
In December 2017, Lauren was diagnosed with recurrent ovarian cancer. She began chemotherapy again and was expected to start a newly approved PARP inhibitor afterward. She remained deeply aware of the risk of recurrence associated with her BRCA1-related cancer while continuing advocacy work and drawing support from her husband, children, parents, and extended family.
Where this story comes from
This is a lay summary of an account first published by Massachusetts General Hospital. Read the original in full
How we source and attribute stories Accuracy and limitations
These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer