Ovarian cancer that later spread to an axillary lymph node

This ovarian cancer diagnosis at a glance

Stage at diagnosis
Stage IV
Sex
Female
Spread to
axillary lymph nodes
Treatment
chemotherapy, surgery and hormone therapy
Outcome
Stable Disease

Treatment course, step by step

  1. She received 3 cycles of chemotherapy followed by debulking surgery and 6 more cycles.
  2. When an axillary lymph-node metastasis appeared, she received another 6 cycles of chemotherapy.
  3. Later peritoneal progression was treated with further chemotherapy and then an aromatase inhibitor.

What happened, in summary

A 69-year-old woman was diagnosed with advanced ovarian cancer after scans showed tumors involving both ovaries, abdominal lymph nodes, the omentum, and peritoneum. She received 3 cycles of chemotherapy, then underwent debulking surgery. Pathology showed an ovarian malignant mixed Müllerian tumor, also called ovarian carcinosarcoma, and the postoperative disease was classified as Stage III.

She completed 6 additional chemotherapy cycles and entered follow-up. More than 2 years later, imaging found an enlarged lymph node in the right armpit. Breast imaging was clear, and removal of the node confirmed that the cancer had spread there from the ovary. This distant nodal recurrence made the disease Stage IV.

She received another 6 cycles of chemotherapy, with scans showing no visible disease afterward. In 2018, however, CA-125 rose and scans found multiple new peritoneal nodules. She underwent further chemotherapy, followed by a different chemotherapy combination and then an aromatase inhibitor.

Her disease remained stable through her last recorded visit in July 2019.

Where this story comes from

This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full

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