Metastatic Follicular Carcinoma Arising From Struma Ovarii

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: right fallopian tube|peritoneum|omentum|bladder…

Four years after diagnosis, she had no evidence of recurrence or metastasis while continuing thyroid-hormone suppression and 6-monthly surveillance.

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Recurrent Ovarian Cancer and Olaparib-Related Skin Toxicity

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|liver

The latest chemotherapy was effective, and she was alive without signs of another recurrence at the last documented follow-up.

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Stage III Ovarian Cancer: Karen's Survivor Story

Patient Info: Karen Howley LaCamera, 50s | Stage III

The REGN4018 clinical trial put Karen’s ovarian cancer into remission, which had lasted nearly a year when the story was written, with follow-up every 6 weeks.

Dana-FarberRead more →

BRCA1 Ovarian Cancer: Mary's Patient Story

Patient Info: Mary Anne Marshall, female

Biomarkers: BRCA1 mutation

She completed a difficult 2-year ovarian cancer treatment course and was alive 4 years into her combined cancer journey.

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Ovarian Cancer Metastasis to the Cervical Spinal Canal

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: brain|cervical intradural extramedullary space

Her neck and shoulder pain resolved after spinal surgery, but she developed recurrent brain disease and died from cachexia 4 months after the spinal operation.

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Stage IV ovarian cancer complicated by a spontaneous vaginal fistula

Patient Info: Anonymized, Female, 50s | Stage IV

After postoperative chemotherapy, she was clinically well and imaging showed no visible tumor during 8 months of follow-up.

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Ovarian Granulosa Cell Tumor Recurring 17 Years After Surgery

Patient Info: Anonymized, Female, 70+

Biomarkers: Weak oestrogen sensitivity

Complete resection was not possible, but debulking relieved pressure on surrounding structures and improved her quality of life. She then continued oncology care with palliative carboplatin and paclitaxel.

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Metastatic Clear Cell Ovarian Cancer Complicated by Treatment-Related Sarcoidosis

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Metastatic Site: peritoneum

During a treatment holiday, biopsy and laboratory evaluation showed treatment-related sarcoidosis rather than ovarian-cancer spread in the enlarged lymph nodes. After prednisone, the sarcoidosis resolved and imaging showed no progression of the clear cell ovarian cancer; she remained clinically well 4 months later.

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BRCA Ovarian Cancer: Christie's Patient Story

Patient Info: Christie Siebel, female

Biomarkers: BRCA mutation

At the latest update, Christie was doing well and having a CA125 blood test every 3 months for ovarian cancer follow-up.

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Immature Ovarian Teratoma Followed by Anti-NMDAR Encephalitis

Patient Info: Anonymized, Female

Biomarkers: AFP 67.6 ng/mL; CA-125 89 at presentation

After 4 cycles of chemotherapy, her neurological deficits fully recovered and she could walk independently, with mild stuttering improving through speech therapy.

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Ovarian Cancer: Shelley's Patient Story

Patient Info: Shelley O’Keefe, female

Shelley was nearing the end of chemotherapy, rebuilding her strength, and returning to demanding golf activity with strong family and community support.

Early-Stage Primary Ovarian Synovial Sarcoma Managed With Surgery and Surveillance

Patient Info: Anonymized, Female, Under 40

Biomarkers: SS18 gene rearrangement confirmed by FISH; CA-125 10.9 U/mL

Serial CT and PET imaging showed no residual disease, recurrence, or metastasis. She remained disease-free 27 months after diagnosis.

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Ovarian Cancer: Dana's Patient Story

Patient Info: Dana Kivel, female

Dana was living with recurrent, metastatic granulosa cell ovarian cancer and taking an aromatase inhibitor for a current tumor.

Stage 4 Ovarian Cancer Discovered During Trigeminal Neuralgia Evaluation

Patient Info: Anonymized, Female, 50s | Stage IV

Three months after surgery, she had recovered well from debulking and 6 total chemotherapy cycles, with complete macroscopic clearance achieved at surgery. Trigeminal-neuralgia symptoms persisted and continued to require daily medication.

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MSI-High Malignant Struma Ovarii With Lung and Liver Metastases 17 Years Later

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Biomarkers: NRAS, and ATM mutations; Ki-67 approximately 15%–29%

Metastatic Site: lungs|liver

She remained asymptomatic and tolerated pembrolizumab without obvious adverse effects after 4 doses, with follow-up imaging planned for metastatic lung and liver disease.

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Rapidly Progressive Stage IIIA2 Ovarian Cancer With Anaplastic Features

Patient Info: Anonymized, Female, Under 40 | Stage Metastatic/Advanced

Biomarkers: CA-125 419 IU/mL; CA19-9 elevated; lactate dehydrogenase elevated

Metastatic Site: lungs|liver

Within 30 days of surgery, the cancer had progressed with a large retroperitoneal nodal mass and new lung and liver metastases. She died from advanced ovarian cancer 5 weeks after surgery.

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Kidney Complications After Treatment for Stage IV Ovarian Cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: peritoneum|left lymph node

No further ovarian-cancer progression was observed during the 10 months after kidney biopsy. The nephrotic syndrome reached partial remission after immunosuppressive treatment was stopped and supportive care continued.

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Aggressive Presumed Ovarian Solid Pseudopapillary Tumor With Widespread Metastases

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|pelvic soft tissue|inguinal lymph…

The disease progressed rapidly across multiple abdominal and nodal sites. She died from disease-related complications 2 months after the oncology consultation while receiving induction chemotherapy.

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Ovarian Cancer: Lauren's Survivor Story

Patient Info: Lauren Wells, Female, Under 40

Lauren was described as cancer-free and making a strong recovery while continuing physical, occupational, and speech therapy.

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Ovarian Cancer: Elle's Patient Story

Patient Info: Elle Simone, female

Elle was dealing with an ovarian cancer recurrence while continuing her work and advocacy.

Stage III Ovarian Cancer: Jackie's Survivor Story

Patient Info: Jackie Page, Female, 50s | Stage III

In remission with no sign of recurrent disease at the September 2020 publication, while continuing treatment on the clinical trial.

Dana-FarberRead more →

Ovarian Fibrosarcoma Recurring Rapidly After Debulking Surgery

Patient Info: Anonymized, Female, 40s

Biomarkers: Ki-67 greater than 20%; vimentin diffusely positive; muscle-specific antigen weakly positive

The cancer recurred with a new pelvic mass and ascites 3 months after surgery. Her condition was too poor for chemotherapy, and she died on the second day of palliative hospital care.

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Emergency Surgery for a Malignant Brenner Tumor Causing Bowel Obstruction

Patient Info: Anonymized, Female, 60s

Biomarkers: CA-125 184.2 U/mL

A 62-year-old woman with a rare malignant Brenner tumor required emergency surgery after the ovarian mass caused bowel obstruction and a sealed perforation.

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Ovarian Cancer: Yvette's Patient Story

Patient Info: Yvette Jives, female

Years after her 2011 ovarian cancer diagnosis, Yvette was leading community education through HERS and supporting other patients through OCRA.