Lung adenocarcinoma that spread to the thyroid 9 years later

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: thyroid

After the thyroid metastasis was removed, she started systemic chemotherapy and remained under oncology management.

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Long-term complete response to targeted therapy for relapsed lung cancer with an EGFR mutation

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: EGFR mutation

Her three most recent scans showed a complete response, and nearly 4 years after relapse she remained free of tumor progression while continuing targeted therapy.

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Stage III Lung Cancer: Bonnie's Patient Story

Patient Info: Bonnie Ulrich, Female, 40s | Stage III

Biomarkers: CA-125 elevated during 2019 workup; no lung cancer driver biomarker reported

After surgery-only Stage I lung cancer and 13 years in remission, Bonnie was later diagnosed with Stage III lung cancer in 2019; the later treatment regimen is not reported.

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Recurrent squamous lung cancer with tumor emboli, acute limb ischemia, brain metastases, and death

Patient Info: Anonymized, Male, 60s | Stage Metastatic/Advanced

Biomarkers: p40-positive; TTF-1-negative; PD-L1 not expressed / no PD-L1 reported in raw case

Metastatic Site: brain/cerebral metastases; tumor emboli in upper and…

The patient developed recurrent acute limb ischemia from tumor emboli, then new cerebral metastases, and died from advanced disease 7 months after the bilateral lower-limb ischemia presentation.

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EGFR-mutated Stage IV lung cancer with later brain progression

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: EGFR exon 19 deletion; acquired EGFR C797S mutation; acquired ROS1 rearrangement

Metastatic Site: brain|bone

She died about 20 months after diagnosis after brain progression and a severe postoperative stroke.

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Lung cancer treated with tislelizumab: rare fluid buildup around the lung as a side effect

Patient Info: Anonymized, Male, 60s

After treatment of the bronchial-stump recurrence, the tumor remained stable. The delayed pleural effusion resolved within 10 days of methylprednisolone, and tumor stability continued for the next 15 months.

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Stage II KRAS Lung Adenocarcinoma: Roy's Survivor Story

Patient Info: Roy, Male, 50s | Stage II

Biomarkers: KRAS

As of May 2026, Roy described being cancer-free/in remission, back to flying professionally, and strong enough to complete his 5th marathon at the Boston Marathon.

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Stage IV ALK Lung Cancer: Jake's Patient Story

Patient Info: Jake, Male, Under 40 | Stage IV

Biomarkers: ALK-positive mutation

Metastatic Site: brain; lung; ankle bone

As of May 2026, Jake was 28 and had lived more than 13 years with Stage IV ALK-positive lung cancer, with ongoing treatment history including targeted therapy, surgeries, radiation, clinical-trial therapy, and recent chemotherapy.

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More than 5 years of disease control with maintenance chemotherapy for Stage IV lung cancer

Patient Info: Anonymized, Male | Stage IV

Biomarkers: KRAS mutation; TP53 mutation

Metastatic Site: brain

After more than 60 months of follow-up and prolonged maintenance chemotherapy, the latest assessment found no evidence of current tumor progression.

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Stage III Non-Small Cell Lung Cancer: Susie's Survivor Story

Patient Info: Susie, Female | Stage III

As of May 2026, Susie described completed surgery, chemotherapy, and radiotherapy for Stage III non-small cell lung cancer and was advocating for smoke-free legislation; no NED status was stated.

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Suspicious right lower-lobe lung nodule reclassified as benign lipoid pneumonia after VATS wedge resection

Patient Info: Anonymized, Female, 40s

Biomarkers: No cancer biomarkers. Pathology showed benign lipoid pneumonia changes, not confirmed cancer.

Final pathology after VATS wedge resection showed benign lipoid pneumonia rather than lung cancer; long-term follow-up was not available.

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No recurrence 7 months after surgery for a rare lung epithelial-myoepithelial cancer

Patient Info: Anonymized, Male, 60s | Stage I

At 7-month follow-up, there was no sign of recurrence after surgery.

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Stage IVA EGFR-mutated lung adenocarcinoma: stable disease on first-line osimertinib

Patient Info: Anonymized, Female, 70+ | Stage IV

Biomarkers: EGFR exon 19 deletion; baseline EGFR exon 20 T790M mutation; ALK IHC negative; PD-L1 TPS 30%; TTF-1-positive

Metastatic Site: pleura; malignant pleural-pericardial adhesions

As of April 2026, she had stable disease for more than 9 months on first-line osimertinib, with no progressive disease, no recurrent pleural effusion, ECOG improvement from 2 to 0, and no treatment-related adverse events.

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Early-stage synchronous lung cancers: tumor-free after lobectomy with delayed respiratory and neuropsychiatric complications

Patient Info: Anonymized, Male, 60s

Biomarkers: No molecular biomarkers reported

More than 3 years after thoracoscopic right middle and lower lobectomy, he remained tumor-free, although he had delayed cardiopulmonary, weight-loss, and neuropsychiatric complications after surgery.

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No recurrence 2 years after surgery for Stage II lung adenocarcinoma

Patient Info: Anonymized, Male, 50s | Stage II

At 2-year follow-up, he remained well with no local recurrence or distant metastasis.

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Stage II Lung Cancer: Michelle's Patient Story

Patient Info: Michelle, Female | Stage II

Receiving ongoing adjuvant treatment after lung cancer first thought to be Stage I was upgraded to Stage IIB because 3 of 18 lymph nodes were positive.

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Stage III lung cancer treatment complicated by immune-related lung inflammation

Patient Info: Anonymized, Male, 60s | Stage III

Biomarkers: EGFR-negative; ALK-negative; ROS1-negative

Mediastinal lymph nodes later enlarged despite additional systemic treatment, prompting radiation and further therapy.

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Stage IV EGFR Lung Cancer: Kelsey's Patient Story

Patient Info: Kelsey, Female, Under 40 | Stage IV

Biomarkers: EGFR mutation; later ALK mutation after progression

Metastatic Site: Bone — pelvis and spine/L5

Living with Stage IV lung cancer on a clinical trial after progression, with current treatment described as working and quality of life improved.

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Stage II EGFR Non-Small Cell Lung Cancer: Daniel's Patient Story

Patient Info: Daniel West, Male, 50s | Stage II

Biomarkers: EGFR positive

As of April 2026, Daniel had shown no evidence of active disease for more than 2 years, while remaining on daily osimertinib through June 2026 and receiving checkups and scans every 3 months for stable monitored lung nodules.

MD AndersonRead more →

Synchronous Stage IA lung adenocarcinoma and grade 4 glioblastoma: lung nodule regressed during brain-cancer therapy

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: Lung molecular biomarkers not reported; glioblastoma biomarker details not summarized in library fields

The Stage IA lung adenocarcinoma was monitored without lung-directed therapy and decreased from 18 mm to 9 mm while CNS-directed glioblastoma treatment continued; she remained alive with no lung cancer progression.

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Stage IIIA lung adenocarcinoma: major pathological response after neoadjuvant immunochemotherapy, complicated by DILI/TEN

Patient Info: Anonymized, Male, 50s | Stage III

Biomarkers: No lung molecular biomarkers reported

At 23 months after thoracoscopic left upper lobectomy, he was clinically stable with no evidence of tumor recurrence; severe postoperative DILI/TEN had improved after stopping the offending drug and intensive supportive treatment.

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Recurrent lung adenocarcinoma with isolated pancreatic metastasis: Whipple resection after discordant tumor-origin testing

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Biomarkers: Pancreatic lesion showed KRAS

Metastatic Site: mediastinal lymph node; pancreas

After prior lung surgery, adjuvant chemotherapy, and later chemoradiation for mediastinal nodal recurrence, an isolated pancreatic lesion was resected by Whipple procedure; post-Whipple recurrence status was not yet reported.

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Recurrent lung cancer with malignant airway compression: Dumon Y-stent improved breathing

Patient Info: Anonymized, Female

Dumon Y-shaped airway stenting restored airway patency, improved left-lung perfusion from 13% to 59%, and reduced dyspnea from MMRC grade 3 to grade 1.

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Stage III EGFR Lung Cancer: Roxanne's Patient Story

Patient Info: Roxanne, Female, 40s | Stage III

Biomarkers: EGFR mutation

Roxanne had Stage III EGFR-mutated lung cancer after surgery found mediastinal lymph-node involvement. As of March 2026, she was living with the long-term effects of surgery, chemotherapy, radiation, and ongoing EGFR-targeted therapy, while also managing the emotional and financial burden of cancer as a single parent.

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