HER2-positive breast cancer on hemodialysis: partial response to T-DM1 then no metabolically active disease

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: Hormone receptor-positive; HER2/neu-positive; E-cadherin-positive; Ki-67 55-60%; luminal B type

As of March 2023, after 12 total cycles of T-DM1 and modified radical mastectomy, PET-CT showed no metabolically active disease, and she continued endocrine therapy and dialysis.

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Rare breast blood-vessel cancer (angiosarcoma) in a teenage girl

Patient Info: Anonymized, Female

Biomarkers: Testing for Li-Fraumeni syndrome and POT1 mutation was inconclusive; no inherited cancer predisposition was established

She remained in remission 3 years after diagnosis and continued annual MRI surveillance of the reconstructed and opposite breasts.

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BRCA2 Breast Cancer: Sue's Survivor Story

Patient Info: Sue Friedman, Female, Under 40

Biomarkers: BRCA2 mutation

As of February 2023, Sue Friedman was a long-term breast cancer survivor and founder of FORCE after a BRCA2-associated breast cancer and recurrence; the video is educational and does not state current active disease, NED, or metastatic status for Sue.

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Stage II Breast Cancer: Renée's Patient Story

Patient Info: Renée, Female, Under 40 | Stage II

Biomarkers: Not genetically inherited; breast cancer linked by her team to prior doxorubicin exposure and total-body radiation

As of February 2023, Renée described stable health, working treatments, good bloodwork, and ongoing long-term hormone/anti-cancer therapy; she did not consider herself cancer-free and preferred survivor/thriver language.

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Rare breast cancer subtype that recurred years later in a more aggressive form

Patient Info: Anonymized, Female | Stage IV

Biomarkers: CD117 focally positive in the transformed component; high Ki-67; hormone-receptor status was unknown at the original diagnosis

Metastatic Site: lungs

One year after treatment for the late chest-wall recurrence, CT showed another local recurrence and metastatic nodules in both lungs. She chose to continue treatment elsewhere.

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Stage IV BRCA Invasive Ductal Carcinoma: Langley's Patient Story

Patient Info: Langley Perer, female, Under 40 | Stage IV

Biomarkers: inherited BRCA mutation

Metastatic Site: brain, bones, leptomeninges

After 1 year on a PARP inhibitor, Langley’s metastatic breast cancer remained in check without progression and some lesions had begun to shrink.

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Triple-Negative Breast Cancer: Lucy's Survivor Story

Patient Info: Lucy E., Female, Under 40

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had been told she was all-clear/cancer-free after chemotherapy, had undergone double mastectomy with staged reconstruction planning, and was continuing close oncology reviews every 3-4 months.

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Stage II Triple-Negative Breast Cancer: Lucy's Patient Story

Patient Info: Lucy, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

As of January 2023, Lucy had gone through fertility preservation, chemotherapy, and double mastectomy for Stage II grade 3 triple-negative breast cancer with BRCA1 mutation; no NED or recurrence status was stated.

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Stage II HER2-Positive Invasive Ductal Carcinoma: Lanie's Patient Story

Patient Info: Lanie Jones, Female, Under 40 | Stage II

Biomarkers: HER2-positive; Li-Fraumeni syndrome / TP53 mutation; BRCA-negative

As of January 2023, Lanie was living with Li-Fraumeni syndrome after 5 cancer diagnoses and was on lifelong maintenance chemotherapy while advocating for genetic testing and specialized surveillance.

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Stage II Breast Cancer: Angelina's Patient Story

Patient Info: Angelina, Female, 50s | Stage II

As of 2023, Angelina was undergoing Stage II breast cancer treatment with DIEP mastectomy, chemotherapy, radiation therapy, and hormone therapy, and was focused on recuperation and future goals.

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Stage II Breast Cancer: Jamie's Patient Story

Patient Info: Jamie, Female, 40s | Stage II

Jamie was newly diagnosed with Stage II breast cancer in 2023 and had not yet started treatment; her plan included mastectomy, chemotherapy, radiation therapy, and targeted therapy.

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Stage II HR-Positive Breast Cancer: Becki's Patient Story

Patient Info: Becki, Female, 40s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-positive

As of 2023, Becki was receiving ongoing treatment for Stage II triple-positive breast cancer after recently completing mastectomy and experiencing chemotherapy-related fatigue, hair loss, and chemo fog.

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Stage 0 Breast Cancer: Jane's Patient Story

Patient Info: Jane | Stage 0

Jane was still receiving treatment after choosing lymphadenectomy for stage 0 breast cancer diagnosed in July 2023.

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Stage I Triple-Negative Breast Cancer: Emma's Patient Story

Patient Info: Emma, Female, 40s | Stage I

Biomarkers: Left breast: triple-negative; right breast: ER-positive

As of the 2023 story, Emma was receiving chemotherapy for Stage I bilateral breast cancer after the initial multimodality plan was changed because of borderline white blood cells.

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Stage III Breast Cancer: Jodi's Patient Story

Patient Info: Jodi | Stage III

Jodi remained on tamoxifen after mastectomy for stage 3 breast cancer and had declined the recommended chemotherapy and radiation therapy.

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Stage IV Breast Cancer: Adriana's Patient Story

Patient Info: Adriana, Female, Under 40 | Stage IV

Adriana was continuing treatment for stage 4 breast cancer and hoped for a complete response. She remained focused on her children despite substantial emotional and financial strain.

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Stage III Breast Cancer: Patricia's Survivor Story

Patient Info: Patricia | Stage III

Patricia was declared cancer-free in 2024 and was in remission while continuing tamoxifen.

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Stage II Breast Cancer: Maiv's Patient Story

Patient Info: Maiv | Stage II

Maiv had completed active treatment and remained on hormone therapy at the time of her story.

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Breast Cancer: Riya's Survivor Story

Patient Info: Riya

Riya’s breast cancer was in remission, with oncology visits every 3 months and additional surgical follow-up every few months.

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Stage II Breast Cancer: Daniela's Survivor Story

Patient Info: Daniela, Female, 50s | Stage II

Daniela was declared cancer-free in March 2024 after mastectomy, lymphadenectomy, chemotherapy, and radiation therapy for Stage II breast cancer.

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Stage II Breast Cancer: Margaret's Patient Story

Patient Info: Margaret | Stage II

Margaret chose mastectomy and hormone therapy and reported no treatment side effects while remaining optimistic about recovery.

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Breast Cancer: Rosie's Patient Story

Patient Info: Rosie

Rosie is currently undergoing radiation therapy and continues to manage treatment effects and fear of recurrence.

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Stage I Breast Cancer: Catriona's Survivor Story

Patient Info: Catriona, Female, 60s | Stage I

Catriona described herself as a breast cancer survivor who had recovered after treatment and was focused on long-term wellbeing and family.

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Stage II Breast Cancer: Sarah's Patient Story

Patient Info: Sarah | Stage II

Sarah remains in active treatment, with the plan changed to focus on chemotherapy, and she is hopeful about completing treatment and returning to daily life.

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