ER-positive breast cancer recurrence after DCIS: chemotherapy, nodal surgery, radiation, and endocrine therapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Recurrent invasive breast cancer: ER-positive; HER2/neu-negative. PR not reported.

Disease-free for 33 months after treatment of ER-positive, HER2-negative invasive breast cancer recurring in the mastectomy skin flap with positive axillary sentinel nodes.

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Male ER/PR-positive breast cancer with contralateral DCIS: mastectomy and tamoxifen with no recurrence

Patient Info: Anonymized, Male, 60s

Biomarkers: Left breast cancer was ER+/PR+ with weak HER2. Right breast had intermediate-grade DCIS; no node spread reported.

Well with no evidence of locoregional recurrence after 5 years of follow-up on adjuvant tamoxifen after bilateral breast surgery.

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Localized breast carcinosarcoma: surgery and chemotherapy with no disease at 54 months

Patient Info: Anonymized, Female, 40s

Biomarkers: Breast carcinosarcoma was ER/PR negative, c-erbB2 5%

Under follow-up with no disease at 54 months after excision, modified radical mastectomy, and 6 courses of chemotherapy for localized breast carcinosarcoma.

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HER2-positive breast cancer with isolated adrenal metastasis: adrenalectomy with no recurrence at follow-up

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Primary breast tumor and adrenal metastasis were HER2-positive and ER/PR negative; adrenal markers supported breast origin.

Metastatic Site: left adrenal gland

Alive in good condition with no evidence of recurrence more than 3 years after adrenalectomy for isolated adrenal metastasis and more than 5 years after the original breast surgery.

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Stage I BRCA1 Breast Cancer: Karen's Patient Story

Patient Info: Karen | Stage I

Biomarkers: BRCA1 mutation

Karen completed surgery and chemotherapy for stage 1 breast cancer and chose prophylactic bilateral mastectomy because of a BRCA1 mutation, while continuing to live with fear of recurrence.

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Stage II Breast Cancer: Martha's Survivor Story

Patient Info: Martha | Stage II

Martha completed treatment and said she had been declared cancer-free, 14 years after her stage II diagnosis.

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Stage III Breast Cancer: Mary's Survivor Story

Patient Info: Mary | Stage III

Mary said she was in remission and no longer required cancer treatment.

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