Triple-negative breast cancer developing beside a large breast cyst

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: ER negative; PR negative; HER2 negative; Ki-67 >50%; p53 negative for overexpression, triple negative

She recovered after treatment with no clinical evidence of regional or distant recurrence.

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Stage III Invasive Ductal Carcinoma: Ximena's Patient Story

Patient Info: Ximena Nardelli, Female, 40s | Stage III

Biomarkers: Hormone receptor-positive

As of February 2020, Ximena had completed mastectomy, 16 chemotherapy sessions, and 21 radiation treatments for Stage III hormone-positive invasive ductal carcinoma and was continuing planned 5-year hormone therapy.

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Early breast cancer followed 19 years later by a radiation-related breast sarcoma

Patient Info: Anonymized, Female, 70+ | Stage I

Biomarkers: Strongly ER-positive; strongly PR-positive.

The stage IA breast carcinoma remained disease-free for 19 years; a later right-breast mass was a separate radiation-induced sarcoma rather than recurrent carcinoma.

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Dramatic chemotherapy response in stage IIIB triple-negative breast cancer

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: ER-negative; PR-negative; HER2-negative; BRCA1-negative; BRCA2-negative; germline FLCN c.1285delC associated with Birt-Hogg-Dubé syndrome; tumor TP53 p.T150fs.

Eighteen months after surgery, she had no recurrence following a dramatic chemotherapy response, bilateral mastectomy, chest-wall radiation, and adjuvant capecitabine.

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Stage IV Breast Cancer: Dan's Patient Story

Patient Info: Dan DiNardo, Male, 40s | Stage IV

Metastatic Site: Left femoral ball/hip; spine; lymph nodes; chest

As of January 2020, Dan was living with metastatic recurrent male breast cancer on ongoing hormone-blocking therapy plus a CDK4/6 inhibitor after surgery and hip radiation; his cancer had shown no growth for 1 year.

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Breast Cancer: Constance's Survivor Story

Patient Info: Constance Porter, Female

As of January 2020, Constance was cancer-free 3 years after breast cancer diagnosis, while living with permanent hair loss, joint pain from anastrozole, and occasional leg cramps.

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ER-negative left breast cancer treated with mastectomy and chemotherapy

Patient Info: Anonymized, Female, 70+

Biomarkers: ER-negative; HER2-negative.

Her later cancer care centered on a separate right-breast primary diagnosed in 2008 and its subsequent metastatic course.

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Stage II Breast Cancer: Catherine's Survivor Story

Patient Info: Catherine, Female, 50s | Stage II

As of 2020, Catherine had completed lumpectomy, chemotherapy, and radiation therapy for Stage II breast cancer and was in remission, while managing fatigue, hair loss, and peripheral neuropathy.

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Stage II Breast Cancer: Cherie's Survivor Story

Patient Info: Cherie, Female, 60s | Stage II

Cherie completed treatment and described herself as being in remission. She remained concerned about recurrence but shifted her focus toward family and retirement.

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Stage I Breast Cancer: Cindy's Survivor Story

Patient Info: Cindy, Female, 40s | Stage I

More than 3 years after diagnosis, Cindy had completed treatment and no longer required medication. She continued to worry about relapse but felt hopeful about the future.

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Stage II Breast Cancer: Marese's Survivor Story

Patient Info: Marese | Stage II

Marese said the breast cancer was in remission after completing active treatment, and she continued hormone therapy to help maintain remission.

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Breast Cancer: Laura's Survivor Story

Patient Info: Laura

Laura said everything was free of malignant cells and was rebuilding her life and career after treatment.

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Stage I Breast Cancer: Susanna's Patient Story

Patient Info: Susanna | Stage I

Susanna was diagnosed with Stage I breast cancer after noticing a swollen breast and completed lumpectomy and chemotherapy while working to preserve normal life and relationships.

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Stage II Breast Cancer: Jaidive's Survivor Story

Patient Info: Jaidive, Female, 40s | Stage II

Jaidive was declared cancer-free on 11 November 2021 after lumpectomy, chemotherapy, radiation therapy, and tamoxifen/hormone therapy for Stage II breast cancer, while continuing specialist appointments and medication.

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Stage III Breast Cancer: Catalina's Survivor Story

Patient Info: Catalina, Female, 50s | Stage III

Catalina described herself as being in remission after oral chemotherapy, while continuing medication for pain.

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Stage IIIA breast cancer treated alongside a synchronous colon cancer

Patient Info: Anonymized, Female, 50s | Stage III

Two years after surgery, she remained well with no CT evidence of metastasis or recurrence while continuing endocrine therapy and six-monthly follow-up.

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Breast Cancer: Alexandria's Patient Story

Patient Info: Alexandria, Female, Under 40

As of December 2019, Alexandria was receiving chemotherapy after single mastectomy and fertility preservation; no final outcome, stage, or biomarker status was stated.

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Stage III Invasive Ductal Carcinoma: Vanessa's Survivor Story

Patient Info: Vanessa Sanders, Female, Under 40 | Stage III

As of November 2019, Vanessa had shown no evidence of disease for 15 years after clinical-trial chemotherapy, breast-conserving surgery and 6 weeks of radiation for Stage III invasive ductal breast cancer.

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Breast Cancer Recurrence in the Liver Mimicking Cirrhosis

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Original cancer: HER2-negative and PR-positive. Liver recurrence: ER-positive.

Metastatic Site: liver

The breast cancer recurred in the liver after 14 years, produced pseudocirrhosis and portal-hypertension complications, and she died from hepatorenal syndrome five weeks after presentation.

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Stage IV HER2-Positive Breast Cancer: Kate's Survivor Story

Patient Info: Kate Watson, Female, Under 40 | Stage IV

Biomarkers: HER2-positive

Metastatic Site: Chest lymph nodes; spine; pelvis; femur

As of October 2019, Kate had been in remission for about 3 years with regular PET scans showing no evidence of active disease, while continuing monthly HER2-targeted maintenance treatment.

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Breast Cancer Recurrence in the Parotid Gland Eight Years Later

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Primary breast tumor: ER-positive and HER2-positive. Parotid metastasis: ER-positive, PR-negative, and HER2-positive.

Metastatic Site: left parotid gland

The isolated parotid metastasis was completely resected, one-month PET-CT showed no significant abnormality, and endocrine therapy continued with exemestane.

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Metastatic Breast Cancer Presenting With Severe Pulmonary Hypertension

Patient Info: Anonymized, Female, Under 40 | Stage IV

Biomarkers: ER-positive; PR-positive.

Metastatic Site: bone; bone marrow

At seven months, she was doing well with a marked response on PET imaging, normalized right-heart pressures, and ongoing systemic treatment with palbociclib.

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Breast Cancer: Brittney's Survivor Story

Patient Info: Brittney Rinella, Female, Under 40

As of August 2019, Brittney was cancer-free 4 years after breast cancer treatment with double mastectomy and 4 chemotherapy rounds plus goserelin injections to help preserve ovarian function; she later gave birth to her son.

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Nocardia Infection Mimicked Breast Cancer Lung Metastases

Patient Info: Anonymized, Female, 50s | Stage III

Biomarkers: ER-negative; PR-negative; HER2-positive.

The lung nodules resolved with antibiotics and proved infectious rather than metastatic; she remained in good health at the last follow-up in January 2019.

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