Stage IV Breast Cancer: Dan's Patient Story

This breast cancer diagnosis at a glance

Stage at diagnosis
Stage IV
Sex
Male
Spread to
Left femoral ball/hip; spine; lymph nodes; chest
Treatment
chemotherapy, surgery, radiation, hormone therapy and targeted therapy
Outcome
Living With Cancer

Treatment course, step by step

  1. 2015 diagnosis of advanced male breast cancer after growing breast lump, bleeding, and skin changes
  2. Completed 4 months of aggressive chemotherapy
  3. Full left mastectomy followed by 35 radiation treatments
  4. Took tamoxifen and was cancer-free for more than 2 years
  5. In 2018, hip pain led to metastatic recurrence in the hip, spine, lymph nodes, and chest
  6. Surgery performed soon after Cleveland Clinic evaluation
  7. Different hormone-blocking medicines plus a CDK4/6 inhibitor were used
  8. Radiation treated the hip; no evidence of cancer growth for 1 year.

What happened, in summary

Dan DiNardo was 49 when he was diagnosed with advanced male breast cancer in 2015. He had first noticed a breast lump, but after a mammogram he was told to return if it changed. For nearly a year, the lump grew. Bleeding and skin changes finally pushed him to seek more care, and scans and biopsy confirmed breast cancer. Dan had 4 months of aggressive chemotherapy, a full mastectomy of his left breast, 35 radiation treatments and hormonal treatment with tamoxifen. He remained cancer-free for more than 2 years. In 2018, hip pain after moving furniture led to a metastatic recurrence. The cancer had spread to the femoral ball in his left hip, with additional spots in the spine, lymph nodes and chest. Dan went to Cleveland Clinic for another opinion. His oncologist, Dr. Halle Moore, was especially concerned about the hip, and orthopedic oncologist Dr. Nathan Mesko evaluated him the same day. Within days, Dan had surgery. His team then started different hormone-blocking medications plus a CDK4/6 inhibitor and treated the hip with radiation. As of January 2020, his cancer had responded well, with no evidence of growth for the past year. He was expected to live with breast cancer and ongoing treatment long term.

Where this story comes from

This is a lay summary of an account first published by Cleveland Clinic. Read the original in full

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