Ovarian Wilms tumor with early abdominal recurrence

Patient Info: Anonymized, Female, Under 40

Biomarkers: WT1-positive; residual tumor MyoD1-positive

After 3 months of radiation and a further 3 months of chemotherapy, PET showed no FDG-avid malignancy.

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Stage III Gastric Cancer: Abdul's Patient Story

Patient Info: Abdul | Stage III

Abdul later stopped further treatment and focused on spending meaningful time with family while living with gastric cancer.

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Colorectal Cancer: Mary's Patient Story

Patient Info: Mary

Within 12 months of the initial treatment course, further tumors were found during follow-up, including one in the liver.

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Stage I Breast Cancer: Audrey's Patient Story

Patient Info: Audrey, Female, 60s | Stage I

Audrey completed quadrantectomy and radiation therapy for Stage I breast cancer and remained on hormone therapy, with lymphatic drainage and physical therapy for lymphedema and pain-related effects.

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Breast Cancer: Laura's Survivor Story

Patient Info: Laura

Laura said everything was free of malignant cells and was rebuilding her life and career after treatment.

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Stage II Colorectal Cancer: Lina's Survivor Story

Patient Info: Lina | Stage II

Some years after her Stage II colorectal cancer diagnosis, Lina said she was cancer-free.

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Stage II Breast Cancer: Marese's Survivor Story

Patient Info: Marese | Stage II

Marese said the breast cancer was in remission after completing active treatment, and she continued hormone therapy to help maintain remission.

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N

Patient Info: N | Stage I

Biomarkers: No inherited BRCA variant identified.

N completed lumpectomy and radiation and continued hormone therapy while adjusting to life after treatment.

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Stage I Breast Cancer: Susanna's Patient Story

Patient Info: Susanna | Stage I

Susanna was diagnosed with Stage I breast cancer after noticing a swollen breast and completed lumpectomy and chemotherapy while working to preserve normal life and relationships.

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Stage I rectosigmoid cancer presenting as full-thickness rectal prolapse

Patient Info: Anonymized, Male, Under 40 | Stage I

He recovered without postoperative complications and was discharged five days after resection of the stage I rectosigmoid cancer.

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Ovarian cancer that later spread to an axillary lymph node

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: axillary lymph nodes

After later peritoneal progression, additional treatment brought the disease to a stable state through her last recorded visit in July 2019.

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Ovarian cancer presenting with axillary lymph-node spread

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: axillary lymph nodes

A 39-year-old woman with high-grade serous ovarian cancer had confirmed spread to an axillary lymph node at diagnosis and underwent extensive cytoreductive surgery.

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Stage IV ovarian cancer with axillary lymph-node spread

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: axillary lymph nodes

A 58-year-old woman with ovarian serous carcinoma and axillary lymph-node spread received chemotherapy, cytoreductive surgery, and postoperative chemotherapy.

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A uterine mass revealed a rare metastasis from lung adenocarcinoma

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: CK7-positive; TTF-1-positive; CK20-negative; PAX8-negative; GATA3-negative.

Metastatic Site: uterus within a leiomyoma

Twelve months after removal of the uterine metastasis, she remained well with normal surveillance imaging and no concern for recurrent disease.

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Stage IIIA breast cancer treated alongside a synchronous colon cancer

Patient Info: Anonymized, Female, 50s | Stage III

Two years after surgery, she remained well with no CT evidence of metastasis or recurrence while continuing endocrine therapy and six-monthly follow-up.

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Stage I colon cancer found during treatment planning for breast cancer

Patient Info: Anonymized, Female, 50s | Stage I

Biomarkers: MSH2, MSH6, MLH1, and PMS2 expression preserved.

Two years after surgery, she remained well with no CT evidence of metastatic disease or recurrence while continuing six-monthly follow-up.

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Nivolumab-related adrenal failure during treatment for metastatic lung cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: brain (left cerebellum)

Her confusion, gastrointestinal symptoms, and hyponatremia improved after glucocorticoid and mineralocorticoid replacement, and she was discharged on ongoing hormone replacement.

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Breast Cancer: Alexandria's Patient Story

Patient Info: Alexandria, Female, Under 40

As of December 2019, Alexandria was receiving chemotherapy after single mastectomy and fertility preservation; no final outcome, stage, or biomarker status was stated.

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Fundic gland-type gastric adenocarcinoma followed over 19 years

Patient Info: Anonymized, male, 70+

Three months after endoscopic resection, no local recurrence was seen while he continued surveillance after declining additional surgery.

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Stage IV Breast Cancer: Natalia's Patient Story

Patient Info: Natalia Padron, Female | Stage IV

Biomarkers: No hereditary breast-cancer mutation identified

Metastatic Site: pelvic organs; ovaries

As of November 2019, Natalia was living about 5 years after a terminal metastatic breast cancer diagnosis, using daily treatment/medications to help control the cancer and advocating for the metastatic breast cancer community.

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Stage III Invasive Ductal Carcinoma: Vanessa's Survivor Story

Patient Info: Vanessa Sanders, Female, Under 40 | Stage III

As of November 2019, Vanessa had shown no evidence of disease for 15 years after clinical-trial chemotherapy, breast-conserving surgery and 6 weeks of radiation for Stage III invasive ductal breast cancer.

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Breast Cancer Recurrence in the Liver Mimicking Cirrhosis

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Original cancer: HER2-negative and PR-positive. Liver recurrence: ER-positive.

Metastatic Site: liver

The breast cancer recurred in the liver after 14 years, produced pseudocirrhosis and portal-hypertension complications, and she died from hepatorenal syndrome five weeks after presentation.

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Pemphigus Vulgaris After Rectal Cancer Surgery and Ileostomy

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Clinicians found no evidence of residual internal malignancy during evaluation of her skin disease, and the pemphigus lesions healed after rituximab with remission maintained for 14 months.

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Colon Cancer Discovered During Emergency Surgery for Intussusception

Patient Info: Anonymized, Female, 70+

She recovered from emergency surgery, was managed conservatively without chemotherapy, and continued regular follow-up after discharge to a nursing home.

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