Rapidly growing Stage I gastric neuroendocrine carcinoma found during close endoscopic follow-up

Patient Info: Anonymized, female, 70+ | Stage I

She remained free of recurrence and metastasis for 18 months after surgery.

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Breast reconstruction complicated by venous congestion in a woman with sickle cell trait

Patient Info: Anonymized, Female, 50s

The reconstructed flap was salvaged after postoperative venous congestion, and she was discharged on therapeutic enoxaparin and aspirin.

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Occult breast cancer found in the axillary lymph nodes during diagnosis of four cancers

Patient Info: Anonymized, Female, 70+

Biomarkers: ER 90% positive; HER2 overexpression; CK19-positive; mammaglobin-positive.

Almost four years after the synchronous cancer diagnoses, she was alive without recurrence and continued letrozole and oncology follow-up.

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Jaw and neck infection mimicked breast cancer spread ten years after treatment

Patient Info: Anonymized, Female, 50s

Ten years after mastectomy and radiation, she remained on adjuvant hormone therapy; the new jaw and neck lesions were actinomycosis rather than breast-cancer spread.

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Stage IV HER2-Positive Breast Cancer: Christine's Survivor Story

Patient Info: Christine Hodgdon, Female, Under 40 | Stage IV

Biomarkers: HER2-positive

Christine had no evidence of disease after 1 year and continued HER2-targeted treatment with regular surveillance scans.

Ovarian Cancer: Kimberly's Survivor Story

Patient Info: Kimberly Richardson, 50s

Kimberly described living with no evidence of disease while undergoing frequent tumor-marker surveillance because granulosa cell tumors can recur.

Stage IV Colorectal Cancer: Howard's Patient Story

Patient Info: Howard Brown, Male, 50s | Stage IV

Metastatic Site: peritoneum|liver

Howard was living with metastatic colon cancer and undergoing CT scans every 90 days, with further treatment depending on whether scans showed recurrence or progression.

Early metaplastic breast cancer treated alongside a separate lung cancer

Patient Info: Anonymized, Female, 60s | Stage I

Biomarkers: ER-negative; PR-negative; HER2-negative.

At 24 months, breast MRI showed no recurrent breast cancer after surgery and six cycles of paclitaxel and carboplatin.

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Severe breast ulceration from pyoderma gangrenosum 17 years after cancer treatment

Patient Info: Anonymized, Female, 70+

Biopsies and imaging found no malignancy in the ulcerated breast, and treatment of infection and pyoderma gangrenosum produced a marked reduction in ulceration after discharge.

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Stage IV Triple-Negative Breast Cancer: Eva's Patient Story

Patient Info: Eva Joseph | Stage IV

Biomarkers: Triple-negative

Metastatic Site: lungs, sternum

On ongoing atezolizumab plus nab-paclitaxel, Eva’s lung and sternum tumors became very small and were being kept at bay while she felt well enough to enjoy short trips.

Stage IV Breast Cancer: Kirby's Patient Story

Patient Info: Kirby Lewis, Male | Stage IV

Biomarkers: ER-positive, PR-positive, HER2-negative

Metastatic Site: lung|spine

Kirby was living with metastatic breast cancer, and his most recent scans showed the right-lung tumor was stable with no signs of progression while he continued fulvestrant and palbociclib.

Stage IV BRCA2 Breast Cancer: Lisa's Patient Story

Patient Info: Lisa Quinn, Female, Under 40 | Stage IV

Biomarkers: Inherited BRCA2 mutation

Metastatic Site: bone, liver

Lisa Quinn died on August 30, 2021, after sharing her experience with metastatic breast cancer and advocating for cancer research funding.

Stage III Breast Cancer: Christine's Survivor Story

Patient Info: Christine Cosby | Stage III

At the latest report, there was no sign of cancer in Christine’s body and she had recovered enough to return to work part time.

Surgery for an isolated splenic metastasis from lung adenocarcinoma

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: spleen

Nine months after removal of the isolated splenic metastasis, follow-up showed no local or disseminated recurrence and she remained under regular lung-cancer surveillance.

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A benign liver granuloma mimicked rectal-cancer recurrence after chemotherapy

Patient Info: Anonymized, Male, 40s

Rectal resection showed a pathologic complete response, and the enlarging liver lesion was repeatedly confirmed as non-malignant granulomatous inflammation rather than metastatic recurrence.

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Portal-vein thrombosis after surgery and chemotherapy for Stage III gastric cancer — Case 2

Patient Info: Anonymized, female, 60s | Stage III

Two months into follow-up after the thrombosis, no hepatic decompensation or liver cirrhosis had been identified.

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Gastric adenocarcinoma with a rare choriocarcinoma component and rapid liver and lung spread

Patient Info: Anonymized, male, 60s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: liver, lung

Rapid liver and lung metastatic progression caused bleeding from a liver metastasis. He declined further treatment and died from hemorrhagic shock 18 days after his final discharge.

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Portal-vein thrombosis after surgery and chemotherapy for Stage III gastric cancer — Case 1

Patient Info: Anonymized, female, 40s | Stage III

At 6 months of follow-up after treatment for the thrombosis, no hepatic decompensation or liver cirrhosis had developed.

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Triple-negative breast cancer developing beside a large breast cyst

Patient Info: Anonymized, Female, 60s | Stage II

Biomarkers: ER negative; PR negative; HER2 negative; Ki-67 >50%; p53 negative for overexpression, triple negative

She recovered after treatment with no clinical evidence of regional or distant recurrence.

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A second breast cancer arising in a previously known cyst

Patient Info: Anonymized, Female, 70+

Biomarkers: ER >95% positive; PR >95% positive; HER2 negative; Ki-67 11–50%; p53 negative for overexpression

She completed right-breast radiation and was continuing anastrozole 1 mg daily as adjuvant endocrine therapy.

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Small hormone-receptor-positive breast cancer found incidentally on chest CT

Patient Info: Anonymized, Female, 70+

Biomarkers: ER 95% positive; PR 70% positive; HER2 negative; Ki-67 11–50%; p53 negative for overexpression

She was receiving adjuvant breast radiation, with at least 5 years of anastrozole planned afterward.

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Multifocal ductal carcinoma in situ presenting with breast discharge and a lump

Patient Info: Anonymized, Female, 50s

Biomarkers: ER >80% positive and PR >80% positive on initial biopsy; ER >95% positive on mastectomy specimen; p53 negative for overexpression

She was recovering after mastectomy with clear margins and 0/2 nodes involved, with endocrine therapy still to be discussed.

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Encapsulated papillary breast cancer in a 62-year-old man

Patient Info: Anonymized, Male, 60s

Biomarkers: ER 95% positive; PR 95% positive; HER2 negative; Ki-67 11–50%; p53 negative for overexpression; hereditary cancer panel negative for reported pathogenic mutations including BRCA1 and PALB2

Mastectomy removed a 2.4 cm encapsulated papillary carcinoma with clear margins and 0/3 sentinel nodes involved; systemic adjuvant therapy was not recommended.

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Stage III Invasive Ductal Carcinoma: Ximena's Patient Story

Patient Info: Ximena Nardelli, Female, 40s | Stage III

Biomarkers: Hormone receptor-positive

As of February 2020, Ximena had completed mastectomy, 16 chemotherapy sessions, and 21 radiation treatments for Stage III hormone-positive invasive ductal carcinoma and was continuing planned 5-year hormone therapy.

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