Stage IV Colorectal Cancer: Amber's Survivor Story

Patient Info: Amber Madden, Female, 40s | Stage IV

Biomarkers: Comprehensive hereditary cancer genetic testing negative; tumor biomarkers not reported

Metastatic Site: Liver

Stage III colon cancer upstaged to Stage IV after liver metastasis was found; after colectomy, chemotherapy, liver surgery, and more chemotherapy, CT scans in May, August, and November 2025 showed no evidence of active cancer.

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Stage IV Gastric Adenocarcinoma: Derek's Survivor Story

Patient Info: Derek Cooney, Male, 40s | Stage IV

Metastatic Site: peritoneum

At his first follow-up in June, scans showed no evidence of disease, and he later completed his pain-management fellowship.

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Stage III Colorectal Cancer: Haley's Survivor Story

Patient Info: Haley Pollack, Female, Under 40 | Stage III

Years into survivorship after Stage IIIC colon cancer treated with surgery, CAPOX chemotherapy, and a recurrence-prevention clinical trial; later continued trial follow-up and advocacy for parents with cancer.

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Stage IV Colorectal Cancer: Lindsay's Patient Story

Patient Info: Lindsay, Female, Under 40 | Stage IV

Metastatic Site: Left ovary; lung spot

As of June 2026, Lindsay was living with Stage IV metastatic colon cancer after FOLFOX chemotherapy, surgery, maintenance chemotherapy, relapse, and a second surgery; exact later treatment details are limited in the extracted text.

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Stage III Colorectal Cancer: Catherine's Patient Story

Patient Info: Catherine, Female | Stage III

Catherine had a complete pathological response after chemoradiation and surgery for Stage III rectal cancer, then continued adjuvant Xeloda/oxaliplatin while waiting for post-treatment scans before accepting an NED label.

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Stage IV Colorectal Cancer: Jackie's Patient Story

Patient Info: Jackie, Female | Stage IV

Biomarkers: Lynch syndrome

Metastatic Site: Not reported

Jackie’s Stage IIIB rectal cancer later recurred as Stage IV/metastatic disease, but early immunotherapy response was strong, with no visible tumor on MD Anderson sigmoid scope about 6 weeks after starting treatment.

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Stage IV rectal mucinous adenocarcinoma with pancreatic metastasis: response to chemotherapy and staged surgery

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: CA 19-9 93.4 U/mL; CEA 3.4 ng/mL; pancreatic lesion biopsy consistent with colorectal origin

Metastatic Site: pancreas

As of May 2026, he had good clinical progress during 5 months of follow-up after staged treatment, including chemoradiation, FOLFOX, abdominoperineal resection, FOLFIRINOX, and Whipple resection of the pancreatic metastasis.

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Stage III Colorectal Cancer: Kristen's Survivor Story

Patient Info: Kristen, Female | Stage III

Completed active treatment for Stage III colon cancer and entered survivorship while managing permanent chemotherapy-induced peripheral neuropathy and chronic pain.

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Stage IV Colorectal Cancer: Mariana's Patient Story

Patient Info: Mariana, Female, Under 40 | Stage IV

Metastatic Site: Ovary; abdominal wall/peritoneum

Ongoing treatment for Stage IV colon cancer with good response during chemotherapy, allowing oxaliplatin to be stopped while continuing treatment every 2 weeks.

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Stage IV Colorectal Cancer: Helen's Survivor Story

Patient Info: Helen, Female, 40s | Stage IV

Metastatic Site: Liver; pelvis

No active tumors / no evidence of disease after liver-directed treatment, liver surgery/ablation, colon resection, and hysterectomy, though she personally described herself as living with cancer and still planned cleanup treatment.

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Gastric cancer surgery and adjuvant treatment followed by endocrine complications

Patient Info: Anonymized, Female, 40s

After cancer treatment, she was hospitalized with severe nutritional and endocrine complications and improved with hormone replacement and nutritional support.

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Stage IV AFP-producing gastric cancer responds to chemotherapy and immunotherapy

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative; pMMR; elevated AFP

Metastatic Site: liver|peritoneum

Imaging showed a sustained partial response, his AFP level returned to normal, and he continued maintenance serplulimab at the latest follow-up.

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My STAGE 4 Colon Cancer was Revealed by a Routine Blood Test! (NO SYMPTOMS!)

Patient Info: Jim, Male, 40s | Stage IV

Metastatic Site: Liver; lungs

Stage IV colon cancer with liver and lung metastases responded strongly to FOLFIRINOX-based chemotherapy, with tumor reduction over 70%, no detectable lung cancer on testing, and ongoing maintenance chemotherapy for remaining liver disease.

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Complete response in Stage IV gastric cancer after chemotherapy, immunotherapy, and surgery

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: HER2-negative; MSS; PD-L1 high

Metastatic Site: liver

He achieved a complete pathologic response and remained free of recurrence for 3 years and 3 months after surgery.

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Recovery from severe liver injury during Stage III gastric cancer treatment

Patient Info: Anonymized, Male, 70+ | Stage III

At the last follow-up in August 2025, imaging showed no recurrence and his liver function remained normal.

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Stage IV Colorectal Cancer: Kristie's Patient Story

Patient Info: Kristie, Female, 50s | Stage IV

Metastatic Site: liver

Kristie is living with Stage IV colon cancer with liver recurrence, prior chemotherapy/radiation/surgery/ablation, and a planned liver resection option after second-opinion review.

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Robotic surgery removes both a kidney tumor and colon cancer in one operation

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: lung

After combined surgery for the sigmoid and kidney tumors, she was receiving S-1, oxaliplatin, and bevacizumab for the remaining lung metastasis.

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Colon cancer patient with insulin autoimmune syndrome after FOLFOX, bevacizumab, and omeprazole

Patient Info: Anonymized, Male, 70+

Biomarkers: No cancer biomarkers reported. Insulin autoimmune syndrome followed chemotherapy/omeprazole exposure.

As of November 2025, the rare insulin autoimmune syndrome episode had improved after glucose supplementation and prednisone acetate, with blood glucose returning to the normal range during postoperative colon cancer treatment.

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ALK-Fusion Gastric Cancer Responds to Alectinib Before Progression

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: DCTN1–ALK fusion; ATM p.E1724*; CDK6 amplification; HER2 negative; mismatch-repair proteins intact; later KRAS amplification

Metastatic Site: bone

Alectinib produced a partial response for about 11.5 months, but the cancer later progressed systemically and she died from uncontrollable gastrointestinal bleeding.

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Stage IV BRAF Colorectal Adenocarcinoma: Pio's Patient Story

Patient Info: Pio, Male, 50s | Stage IV

Biomarkers: BRAF V600 mutation

Metastatic Site: peritoneum; liver; left lung nodules

After initial chemotherapy produced mixed results and May imaging showed growth, BRAF/EGFR-directed treatment led to a marked improvement on July scans.

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Kidney complication after switching colorectal cancer chemotherapy regimens

Patient Info: Anonymized, Male, 70+ | Stage IV

Metastatic Site: liver

The cancer had worsening liver metastases when FTD/TPI began. After treatment was stopped, steroid therapy resolved edema within 1 month and proteinuria returned to baseline 2.5 months after admission; the later cancer course was not established.

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Stage IV BRAF Colorectal Cancer: Jackson's Patient Story

Patient Info: Jackson, Male, Under 40 | Stage IV

Biomarkers: BRAF mutation

Metastatic Site: Liver; peritoneal wall

Jackson had Stage IV BRAF-mutated colon cancer with extensive liver disease and later confirmed peritoneal-wall tumors. His treatment response was strong, with about 90% of liver disease estimated gone, but he remained on active treatment with possible future HIPEC evaluation. As of September 2025, he was responding well but not cancer-free.

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Stage IV transverse colon cancer with NTRK fusion: entrectinib response followed by fatal PTTM

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: RAS/BRAF wild type, low TMB. CEA and CA19-9 were elevated before entrectinib and fell with response.

Metastatic Site: peritoneum, greater omentum, pleura,…

He died 7 weeks after hospitalization from pulmonary tumor thrombotic microangiopathy causing severe pulmonary hypertension and right-heart failure, despite biochemical and ascites response to entrectinib.

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Stage III Colorectal Cancer: Nicole's Survivor Story

Patient Info: Nicole, Female, Under 40 | Stage III

Nicole completed surgery and 6 months of chemotherapy for Stage III sigmoid colon cancer. As of August 2025, she described good scans and bloodwork while managing survivorship issues, including lasting chemotherapy-related nerve damage.

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