Gastric adenocarcinoma is found after repeated ulcer biopsies remain negative

Patient Info: Anonymized, Male, 40s

He recovered well after surgery, received adjuvant chemotherapy and continued regular outpatient follow-up.

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Ovarian Cancer Recurrence Complicated by a Benign Surgical Stitch Reaction

Patient Info: Anonymized, female, 40s | Stage III

Diffuse peritoneal relapse was confirmed, and she remained on third-line chemotherapy with persistent evidence of ovarian cancer.

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Gastric adenocarcinoma causes SIADH through ectopic ADH secretion

Patient Info: Anonymized, Male, 60s

Biomarkers: ADH-positive tumor cells

He died from gastric-cancer progression 1.6 years after diagnosis despite surgery and chemotherapy.

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AFP-producing gastric adenocarcinoma causes biliary obstruction without liver metastasis

Patient Info: Anonymized, Female, Under 40

Biomarkers: markedly elevated serum AFP

After further chemotherapy became impossible, she was discharged in stable condition to Saint Vincent Island for comfort-focused care.

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Ovarian Cancer Recurs as a Solitary Splenic Metastasis Six Years Later

Patient Info: Anonymized, female, 50s | Stage IV

Metastatic Site: spleen

After removal of the solitary splenic metastasis, she returned to gynecologic oncology and received another course of paclitaxel and carboplatin.

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Gastric cancer recurs in the spermatic cord 7 years after treatment

Patient Info: Anonymized, Male, 40s | Stage IV

Metastatic Site: epididymis, spermatic cord

At 26 months after orchiectomy, he was doing well with no evidence of recurrence, more than 9 years after his original gastric-cancer surgery.

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Gastric cancer recurs in the spermatic cord after 6 years without recurrence

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: spermatic cord

At 20 months after orchiectomy, he was stable with no recurrence, more than 7 years after treatment of his original gastric cancer.

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Signet-ring gastric cancer with repeated recurrences and a late adrenal metastasis

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: left adrenal gland

At 12 months after resection of the adrenal metastasis, no definite recurrence was found, roughly 7 years after the original gastric-cancer surgery.

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Gastric adenocarcinoma recurs in the adrenal gland 6 years after gastrectomy

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: left adrenal gland

At 13 months after resection of the adrenal metastasis, imaging and tumor-marker follow-up found no evidence of recurrence, placing him more than 7 years beyond the original gastrectomy.

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Fertility-Sparing Surgery for Stage I Endometrioid Ovarian Cancer

Patient Info: Anonymized, female, Under 40 | Stage I

Biomarkers: BRCA1/2 negative

She had two spontaneous pregnancies after treatment and remained without evidence of disease at 46 months.

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Synchronous Stage IA breast cancer and Stage IIA lung adenocarcinoma: disease-free after surgery and adjuvant therapy

Patient Info: Anonymized, Female, 60s | Stage I

Biomarkers: Breast tumor: ER/PR positive, HER2 negative. Lung tumor: KRAS/EGFR wild type, ALK rearrangement not detected.

As of April 2014, more than 2 years of follow-up showed no recurrent disease after treatment of synchronous Stage IA breast cancer and Stage IIA lung adenocarcinoma.

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Stage III low rectal cancer: complete response to mFOLFOX6 plus panitumumab and sphincter-preserving surgery

Patient Info: Anonymized, Male, 50s

Biomarkers: KRAS wild-type

As of March 2014, he was alive without evidence of recurrence 3 months after surgery, after complete pathologic response to neoadjuvant mFOLFOX6 plus panitumumab followed by intersphincteric resection and adjuvant UFT/leucovorin.

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Mixed epithelial and mesenchymal metaplastic breast carcinoma: no recurrence 1 year after surgery and adjuvant therapy

Patient Info: Anonymized, Female, 40s

Biomarkers: Mixed metaplastic breast cancer: epithelial part ER/PR/HER2-positive; mesenchymal part ER/PR-negative with weak HER2. Ki-67 ~20%.

As of March 2014, she was doing well with no recurrence or metastasis 1 year after modified radical mastectomy, adjuvant CEF/Taxotere chemotherapy, and tamoxifen.

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The Loss of a Mother

Patient Info: Anonymized, Female | Stage IV

She died in February 2013 after living with Stage IV gastric cancer while her daughter cared for her through treatment.

Stage III BRCA1 Ovarian Cancer: Meredith's Survivor Story

Patient Info: Meredith Ippolito, female | Stage III

Biomarkers: BRCA1 mutation

Meredith was told she was cancer-free in April 2009 and continued follow-up visits every 6 months.

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Stage IIIB lung adenocarcinoma with separate papillary renal cell carcinoma: doing well more than 6 years after revised diagnosis

Patient Info: Anonymized, Female, 40s | Stage III

Biomarkers: Lung tumor: TTF-1-positive; PET-avid. Kidney lesion: PET-negative; later papillary renal cell carcinoma. No lung molecular biomarkers reported.

As of February 2014, she was doing well more than 6 years after the initial diagnosis, after the diagnosis was revised from presumed Stage IV lung cancer to Stage IIIB lung adenocarcinoma plus a separate papillary renal cell carcinoma.

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Gastric Cancer: Sara's Patient Story

Patient Info: Sara Souto Strom, Female

After treatment, Sara returned to an active life and continued her work as a cancer researcher.

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Cecal cancer revealing Muir-Torre syndrome with an MSH2 mutation

Patient Info: Anonymized, female

Biomarkers: MSI-high; loss of MSH2 expression; truncating MSH2 mutation

A woman with multiple sebaceous tumors and a strong family history of colorectal cancer was found to have MSI-high cecal cancer and an MSH2 mutation consistent with Muir-Torre syndrome.

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Ovarian Cancer: Betty's Survivor Story

Patient Info: Betty White, female

Betty had remained cancer-free for nearly 16 years after chemotherapy at the time of the story.

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Stage IV NSCLC: near-complete response despite severe docetaxel-induced diarrhea

Patient Info: Anonymized, Male, 70+ | Stage IV

As of October 2013, he had completed 6 cycles of weekly docetaxel-cisplatin with dose reduction and supportive care, resulting in a near-complete response.

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Stage IV Ovarian Cancer: Bre's Patient Story

Patient Info: Bre Tipps, female, Under 40 | Stage IV

A recent CT scan showed the remaining tumors calcifying and dying during hormonal therapy, although the patient expected to need ongoing ovarian cancer treatment.

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Stage IV primary gastric choriocarcinoma reaches 9 years with no evidence of disease

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: liver, lungs

She remained alive with no evidence of disease for 9 years after radiofrequency ablation, more than 9 years after the original diagnosis.

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Early gastric cancer returns in bone after an 8-year disease-free interval

Patient Info: Anonymized, Male, 50s | Stage IV

Metastatic Site: bone

After an 8-year disease-free interval, he developed bone metastasis, received chemotherapy, developed disseminated intravascular coagulopathy and died in August 2011, nearly 10 years after the original diagnosis.

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Breast invasive ductal carcinoma with coexisting inflammatory myofibroblastic tumor: disease-free after mastectomy, TAC, and tamoxifen

Patient Info: Anonymized, Female, Under 40

Biomarkers: Breast cancer: ER/PR-positive with HER2 2+ and p53-positive. Separate inflammatory myofibroblastic tumor had ALK/vimentin/actin/S-100 markers.

As of August 2013, she remained disease-free 2 years after modified radical mastectomy, 6 courses of TAC chemotherapy, and tamoxifen.

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