Cancer Stories
Lung CancerPatient Info: Anonymized, Male, 50s
Biomarkers: No molecular biomarkers reported for SCLC. Bladder biopsy during cystitis showed mostly CD3/CD8-positive T-cell inflammation.
Lung CancerSmall Cell Lung Cancer: Montessa's Survivor Story
Patient Info: Montessa, Female, Under 40
Lung CancerPatient Info: Anonymized, Male, 60s
Biomarkers: CSF positive for anti-NMDAR antibodies; no tumor molecular biomarkers reported
Lung CancerPatient Info: Anonymized, Male, 60s | Stage Metastatic/Advanced
Biomarkers: ProGRP and NSE were elevated at diagnosis. Tumor molecular biomarkers were not reported; diabetes antibodies were negative.
Metastatic Site: left submandibular region / adjacent lymph nodes
Lung CancerExtensive-stage small-cell lung cancer with malignant superior vena cava syndrome
Patient Info: Anonymized, Male, 60s
Lung CancerPatient Info: Anonymized, Female, 60s | Stage IV
Metastatic Site: bone (axial skeleton and skull)
Lung CancerSmall Cell Lung Cancer After a Remote Chest Gunshot Injury
Patient Info: Anonymized, male
Lung CancerPatient Info: Anonymized, Male, 60s | Stage IV
Biomarkers: Small-cell lung cancer markers included TTF-1/chromogranin-A with Ki-67 90%. Paraneoplastic testing showed GABA-B receptor IgG positive.
Metastatic Site: adrenal glands, diaphragmatic lymph nodes, lungs,…
Lung CancerFour EGFR-Mutated Lung Cancers That Changed Form After Osimertinib
Patient Info: Anonymized, female, 50s
Biomarkers: EGFR exon 19 deletion; TP53 p.D259V
Lung CancerFour EGFR-Mutated Lung Cancers That Changed Form After Osimertinib — Case 2
Patient Info: Anonymized, female, 60s
Biomarkers: EGFR exon 19 deletion; TP53 p.R110P; acquired MET amplification
Lung CancerExtensive-stage small-cell lung cancer with serplulimab-associated diabetes: care ongoing
Patient Info: Anonymized, Male, 60s | Stage IV
Biomarkers: Tumor biomarkers not reported. Diabetes workup after immunotherapy: autoantibodies negative, C-peptide very low.
Lung CancerExtensive-stage small-cell lung cancer with serplulimab-associated diabetes
Patient Info: Anonymized, Male, 70+ | Stage IV
Biomarkers: Tumor biomarkers not reported. Diabetes autoantibodies were negative, C-peptide was low, and hypothyroidism labs were severe.
Lung CancerExtensive-stage small-cell lung cancer with immune-related diabetes and stable disease at 2 years
Patient Info: Anonymized, Female, 60s | Stage IV
Biomarkers: Tumor PD-L1 not reported. Immune-related diabetes showed very low C-peptide and negative diabetes autoantibodies; thyroiditis also occurred.
Metastatic Site: pancreas; pleura/pleural effusion; mediastinal lymph…
Lung CancerPatient Info: Anonymized, Male, 70+ | Stage IV
Biomarkers: PD-L1 <1%
Metastatic Site: bone (C2, T10, sacral vertebrae); malignant pleural…
Lung CancerPatient Info: Anonymized, Male, 40s
Biomarkers: PD-L1 CPS 1
Lung CancerPatient Info: Anonymized, Female, 50s | Stage IV
Biomarkers: especially at recurrence. PD-L1 was not reported.
Metastatic Site: liver; right hilar and mediastinal lymph nodes
Lung CancerPatient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: Small-cell lung cancer markers included CD56, CgA and TTF-1; Ki-67 was 80%.
Metastatic Site: brain, right adrenal gland, left adrenal gland
Lung CancerLimited-stage small cell lung cancer with no recurrence after 14 years
Patient Info: Anonymized, Female, 60s
Biomarkers: SCLC markers: CD56/TTF-1 positive. Essential thrombocythemia had JAK2 . Cancer predisposition gene testing was negative.
Lung CancerPatient Info: Anonymized, Male, 40s | Stage IV
Metastatic Site: left adrenal gland
Lung CancerSmall-Cell Lung Cancer With Later Brain and Other Metastases in a Woman With COPD
Patient Info: Anonymized, female, 50s | Stage IV
Metastatic Site: central nervous system
Lung CancerSmall Cell Lung Cancer That Spread to the Ear Canal
Patient Info: Anonymized, male, 70+ | Stage IV
Metastatic Site: external auditory canal, middle ear, pancreas, bone
Lung CancerExtended-stage small cell lung cancer with breast metastasis: complete response after pembrolizumab
Patient Info: Anonymized, Female, 60s | Stage IV
Biomarkers: TMB-high, microsatellite stable; TP53/PTEN mutations, and SOX2/PIK3CA/FGF12 amplifications.
Metastatic Site: breast
Lung CancerEGFR-Mutant Lung Adenocarcinoma That Transformed to Small Cell Lung Cancer
Patient Info: Anonymized, female, 40s | Stage IV
Biomarkers: EGFR exon 19 deletion; acquired EGFR T790M mutation
Metastatic Site: liver
Etoposide Desensitization After Cardiac Arrest in Metastatic Small Cell Lung Cancer
Patient Info: Anonymized, female, 60s | Stage IV
Metastatic Site: brain