Stage IV gastric adenocarcinoma progresses despite multiple chemotherapy approaches for peritoneal metastases

Patient Info: Anonymized, Male, Under 40 | Stage IV

Metastatic Site: peritoneum

The cancer progressed during second-line treatment, and he died from tumor-related complications in April 2017, about 16 months after his December 2015 admission.

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Metastatic signet-ring gastric cancer spreads diffusely to the thyroid and skin

Patient Info: Anonymized, Female, 70+ | Stage IV

Metastatic Site: thyroid, skin

She died 1 month after hospitalization after her condition worsened despite supportive care.

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Stage IV gastric cancer with peritoneal metastases controlled for years with intraperitoneal chemotherapy

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: peritoneum, bone

She had survived 5 years 2 months after diagnosis of peritoneal carcinomatosis, despite later suspected ovarian metastases, confirmed bone metastases and recurrent peritoneal disease.

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Stage IV gastric adenocarcinoma causes inferior vena cava compression and severe leg swelling

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: HER2-positive

Metastatic Site: omentum

At the latest follow-up, she was receiving cycle 5 of paclitaxel and trastuzumab. Her appetite, energy and leg edema had improved, although abdominal bloating persisted.

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Severe gastrointestinal bleeding and perforation during apatinib treatment for metastatic gastric cancer

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: HER2 IHC 2+; FISH negative for HER2 amplification

Metastatic Site: peritoneum, ileum

She died on February 23, 2015 after gastrointestinal perforation, septic shock and multiple organ dysfunction during progressive metastatic disease.

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