Stage I Invasive Lobular Carcinoma: Tammy's Survivor Story

Patient Info: Tammy, Female, 60s | Stage I

As of October 2025, Tammy had fully recovered and remained disease-free after Stage I invasive lobular breast cancer treated with partial mastectomy and a targeted week-long radiation course, with ongoing follow-up monitoring.

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Stage II HR-Positive Breast Cancer: Jennifer's Survivor Story

Patient Info: Jennifer Njathi, Female, 40s | Stage II

Biomarkers: Triple-positive; ER-positive; PR-positive; HER2-positive

As of October 2025, Jennifer was more than 1 year past treatment for triple-positive Stage IIA breast cancer and had a recent clear MRI.

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ER/PR/HER2-positive breast cancer: gallbladder, liver, lung, pleural, and bone metastases after incomplete adjuvant therapy

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: Triple-positive breast cancer. Gallbladder metastasis kept ER/PR/HER2 positivity and Ki-67 >40%; markers supported breast origin.

Metastatic Site: gallbladder, liver, lung/pleura, bone

The patient died 3 years and 10 months after lumpectomy after metastatic ER/PR/HER2-positive breast cancer involved the gallbladder, liver, lungs/pleura, and bones following incomplete adjuvant therapy and loss to surveillance.

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Stage II Triple-Negative Breast Cancer: Jennifer's Survivor Story

Patient Info: Jennifer Rancik, Female, Under 40 | Stage II

Biomarkers: BRCA1 mutation; triple-negative breast cancer

Jennifer entered remission in October 2017 after Stage II triple-negative breast cancer treatment and, as of October 2025, reported doing great and being off medications except occasional Zometa.

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Stage II Breast Cancer: Basma's Patient Story

Patient Info: Basma, Female, 40s | Stage II

As of October 2025, Basma had completed chemotherapy, tumor-removal surgery, and radiation with clear results and full recovery, while continuing daily oral medication and an injection every 3 months for prevention.

Stage IV Invasive Lobular Carcinoma: Nikoo's Patient Story

Patient Info: Nikoo, Female, 40s | Stage IV

Biomarkers: BRCA1/2 negative; PIK3 mutation reported on liquid biopsy

Metastatic Site: Peritoneal/abdominal lining; abdominal lymph nodes

Nikoo had Stage I invasive lobular breast cancer in 2003 and developed Stage IV metastatic recurrence in 2022 after about 19 years. As of October 2025, she was living with metastatic lobular breast cancer, had moved through multiple systemic options, and was participating in a Phase 1 clinical trial.

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Stage IIIA triple-negative breast cancer with hypercalcemia from parathyroid adenoma

Patient Info: Anonymized, Female, 50s | Stage III

Biomarkers: ER-negative; PR-negative; HER2-negative

As of October 2025, evaluation for post-chemotherapy weakness showed no local breast cancer recurrence, no lymphadenopathy, and no bone metastases; hypercalcemia resolved after parathyroid adenoma removal while breast cancer care remained ongoing.

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Triple-negative metastatic breast cancer with pituitary metastasis: symptom relief after debulking

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Pituitary metastasis was triple-negative breast cancer with no HER2 amplification.

Metastatic Site: liver; bone/skull; right breast; left orbit/optic…

Transsphenoidal debulking relieved visual symptoms and 6-month MRI showed no pituitary recurrence, while known metastatic breast cancer at other sites remained part of her ongoing cancer course.

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Stage II central breast cancer: oncoplastic breast-conserving surgery with hatchet and AICAP flaps

Patient Info: Anonymized, Female, 70+ | Stage II

She completed oncoplastic breast-conserving surgery and radiotherapy; 3 months after radiotherapy, the reconstructed breast remained soft with sufficient volume and favorable cosmetic results.

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Stage IIA breast collision tumor: disease-free after surgery and adjuvant therapy

Patient Info: Anonymized, Female, 70+ | Stage II

Biomarkers: Two breast tumor parts were ER-positive; one HER2-low/negative and one HER2-positive. BRCA testing was suggested but not done.

Four years after surgery, she remained disease-free after mastectomy, adjuvant chemotherapy, HER2-targeted therapy, and endocrine therapy.

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Luminal A solid papillary breast carcinoma with lung metastasis: mastectomy and lung resection, PET-CT clear

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Initial breast tumor and lung metastasis were ER/PR positive, HER2 0

Metastatic Site: lung

About 40 days after lung surgery, PET-CT showed no abnormalities; the specialist recommended regular follow-up without additional antitumor drug therapy, and she was alive and in good condition.

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Breast Cancer: Theresa's Survivor Story

Patient Info: Theresa, Female, 40s

Biomarkers: Hormone receptor-positive; exact receptors not fully specified

Theresa completed treatment for multiple cancers, including bilateral mastectomy/reconstruction for breast cancer and later excision plus 3 months of radiation for chest-wall recurrence. As of October 2025, she described being about 6 years out from the later recurrence, with no other cancer found on scans.

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Hormone receptor-positive male breast cancer: spontaneous regression after biopsy and mastectomy

Patient Info: Anonymized, Male, 50s

Biomarkers: ER-positive; PR-positive; HER2-negative; p63 staining confirmed myoepithelial cells in residual benign cystic lesion

Mastectomy and axillary clearance showed no residual invasive carcinoma or carcinoma in situ, with clear margins; he recovered well and began adjuvant tamoxifen because of the original ER/PR-positive biopsy.

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Stage IV Breast Cancer: Dana's Patient Story

Patient Info: Dana, Female, 50s | Stage IV

Metastatic Site: Liver; bones; lymph nodes

As of October 2025, Dana was living with stable Stage IV metastatic breast cancer involving the liver, bones, and lymph nodes, controlled with targeted therapy and hormone blockers while also managing bipolar disorder and treatment-related mental health effects.

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Paget disease, bilateral apocrine breast carcinomas, and primary breast follicular lymphoma after aromatase inhibition

Patient Info: Anonymized, Female, 70+

Biomarkers: Initial breast cancer was ER/PR-positive, HER2-negative. Later apocrine cancers were triple-negative with AR/ER-beta markers. Lymphoma had IgH::BCL2.

As of September 2025, she was alive 3 years after bilateral mastectomy and observation for Stage Ie follicular lymphoma, with no recurrence of either breast carcinoma or lymphoma.

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Breast Cancer: Karin's Patient Story

Patient Info: Karin, Female, 50s

As of September 2025, Karin was living with recurrent incurable breast cancer, felt healthy and fit, and had chosen mastectomy with reconstruction, ovary removal, anti-hormone therapy, and complementary therapies after recurrence.

PT3N0 triple-negative breast carcinosarcoma: surgery, EC chemotherapy, radiation, disease-free at 26 months

Patient Info: Anonymized, Female, 50s

Biomarkers: Triple-negative breast carcinosarcoma. INI1 was retained

She was clinically free of disease at her last follow-up in April 2025, 26 months after treatment completion; December 2024 mammography showed no suspicious changes.

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Stage 0 ER-positive DCIS: mastectomy without adjuvant therapy, followed by successful pregnancy

Patient Info: Anonymized, Female, 40s | Stage 0

Biomarkers: ER-positive; PgR-positive; HER2-negative; nuclear grade 2; comedo type; negative margins; no lymph node involvement

She completed surgical treatment for Stage 0 DCIS with negative margins and no lymph node involvement, avoided adjuvant therapy, resumed assisted reproductive treatment, and delivered a healthy male infant.

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HER2-positive invasive lobular breast cancer in a transgender man: disease-free after multimodality care

Patient Info: Anonymized, transgender man, 70+ | Stage III

Biomarkers: HER2-positive invasive lobular breast cancer, ER/PR negative

Nearly 2 years after diagnosis, he remained disease-free while continuing survivorship care and counseling after discontinuing testosterone therapy.

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Stage IV Triple-Negative Breast Cancer: Melissa's Patient Story

Patient Info: Melissa Fouts, Female | Stage IV

Biomarkers: ER-negative; PR-negative; HER2-negative

Metastatic Site: Outside the lungs / pleural area

As of September 2025, Melissa had been on low-dose eribulin for almost 7 years; 6 metastatic nodules outside the lungs had shrunk and stabilized, with 3 nearly undetectable on scans.

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Triple-negative breast pleomorphic adenocarcinoma: disease-free after mastectomy and one course of capecitabine

Patient Info: Anonymized, Female, 70+

Biomarkers: Triple-negative breast pleomorphic adenocarcinoma with PIK3CA mutation; markers supported the diagnosis.

As of September 2025, she had 2 years of disease-free survival after left total mastectomy, sentinel lymph node exploration, and 1 course of oral capecitabine.

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Stage I Breast Cancer: Angela's Patient Story

Patient Info: Angela George, Female, 40s | Stage I

Biomarkers: Not explicitly reported; Herceptin was given

As of September 2025, Angela was approaching 5 years from her Stage I breast cancer diagnosis, had completed bilateral mastectomy, chemotherapy, Herceptin, and oophorectomy, and remained on daily estrogen-reducing medication with oncology visits every 6 months; the source does not explicitly state NED.

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Invasive Ductal Carcinoma: Meghan's Patient Story

Patient Info: Meghan McLyman, female, 40s

Meghan was doing well and had returned to her normal life, teaching dance and volunteering as a peer mentor.

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Stage IV Breast Cancer: Maria's Patient Story

Patient Info: Maria, Female | Stage IV

Metastatic Site: Bone (spine, clavicle, rib, thigh bone, scapula);…

Maria initially had a clean PET scan after chemotherapy, surgery, radiation, and targeted/endocrine therapy, but later developed Stage IV metastatic breast cancer involving multiple bone sites, with lung and cervical-region involvement also described. As of September 2025, she remained on treatment and did not have an available clinical trial option.

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