Triple-negative breast cancer: partial response to TAC chemotherapy

Patient Info: Anonymized, Female, 70+ | Stage III

Biomarkers: Triple-negative breast cancer with EGFR positivity and high Ki-67; BRCA1 staining was positive by IHC.

After 1 cycle of TAC chemotherapy, the large ulcerated breast tumor shrank enough for surgery. Radical mastectomy with adjacent flap transfer achieved clear margins and no nodal metastatic cancer; she was recovering at home while awaiting planned postoperative AC-T chemotherapy.

PubMed CentralRead more →

Inflammatory Breast Cancer: Shirley's Patient Story

Patient Info: Shirley Joseph

Shirley completed chemotherapy and a July 2024 mastectomy, with radiation and hormonal therapy still planned.

Dana-FarberRead more →

Breast Cancer: Krista's Patient Story

Patient Info: Krista Brown, Female

Biomarkers: Pathogenic ATM mutation; hormone receptor-positive; HER2-negative; Oncotype DX score 1/100

As of August 2024, Krista had completed mastectomy/reconstruction surgery and was continuing adjuvant tamoxifen with low reported recurrence risk.

The Patient StoryRead more →

Triple-negative breast cancer: partial response to immunotherapy combination

Patient Info: Anonymized, Female, 40s | Stage IV

Biomarkers: Initial tumor: ER-negative; PR-negative; HER2-negative; Ki-67 >80%

Metastatic Site: left lung, neck lymph nodes, mediastinal lymph nodes

Metastatic triple-negative breast cancer had a partial response after 9 months of pembrolizumab plus MK-4830, with reduced tumor burden, decreased lung and mediastinal metastases, and no new metastatic lesions; immunotherapy continued after prednisone controlled a grade 2 lichenoid eruption.

PubMed CentralRead more →

Triple-Negative Pleomorphic Lobular Breast Cancer in a BRCA1 Carrier

Patient Info: Anonymized, Female, Under 40

Biomarkers: Triple-negative, BRCA1 pathogenic mutation

Surgery after neoadjuvant treatment showed a complete pathologic response with no cancer in the 2 sampled sentinel lymph nodes.

PubMed CentralRead more →

Right-Sided Ductal Carcinoma in Situ Before a Second Breast Cancer

Patient Info: Anonymized, female, 60s

Biomarkers: ER-positive; PR-positive; HER2 1+

A woman treated for right-sided ductal carcinoma in situ in 2018 later developed a separate invasive cancer in the opposite breast.

PubMed CentralRead more →

HER2-Positive Breast Cancer That Spread to the Cervix

Patient Info: Anonymized, female, 60s | Stage IV

Biomarkers: HER2-positive; ER and PR less than 1% in the left breast tumor

Metastatic Site: cervix, esophagus, mediastinal lymph nodes

Cervical metastasis showed a local complete response after brachytherapy, but systemic disease later progressed to the esophagus. She died after 4 months of nutritional support and palliative treatment.

PubMed CentralRead more →

Stage 0 DCIS breast cancer: disease-free after treatment

Patient Info: Erica, Female | Stage 0

Biomarkers: BRCA-negative

As of August 2024, Erica described herself as cancer-free after Stage 0 DCIS treated with double mastectomy and reconstruction, with peace of mind about recurrence risk.

The Patient StoryRead more →

Stage 3 infiltrating ductal carcinoma treated with radical mastectomy

Patient Info: Anonymized, Male, 50s | Stage III

Biomarkers: Breast cancer was ER/PR positive, HER2 negative

The patient recovered fully after right radical mastectomy and complete axillary dissection for Stage III male breast infiltrating ductal carcinoma; adjuvant therapy and recurrence follow-up were not reported in the extracted case text.

PubMed CentralRead more →

Stage 4 invasive ductal carcinoma: metastatic disease with bone involvement managed successfully

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: ER <1%; PR 0%; HER2 score 3+; Ki-67 60%

Metastatic Site: bone (12th thoracic vertebra/T12)

Stage IV HER2-positive breast cancer had improved T12 bone metastasis, major breast-tumor regression on trastuzumab deruxtecan, and pathologic complete response in the breast after mastectomy; durable systemic disease status was not reported.

PubMed CentralRead more →

Breast cancer history with painful implant capsule: no recurrence or BIA-ALCL found

Patient Info: Anonymized, Female, 40s

Biomarkers: Implant/capsule pathology showed necrotic tissue only; no tumor cells, CD30 signal, bacteria

The painful implant/capsule episode did not show breast cancer recurrence or BIA-ALCL on pathology; symptoms and cancer concern improved after implant removal, while oral flumatinib maintenance for acute B-lymphoblastic leukemia continued.

PubMed CentralRead more →

Low-Grade Adenosquamous Breast Cancer With High-Grade Transformation

Patient Info: Anonymized, female, 50s

Biomarkers: Focal ER-positive; PR-negative; HER2-negative; EGFR-positive

No tumor recurrence or metastasis was observed during follow-up after surgery and chemotherapy.

PubMed CentralRead more →

Stage I Invasive Lobular Carcinoma: Jessica's Patient Story

Patient Info: Jessica, Female, 40s | Stage I

Biomarkers: Myriad genetic testing negative; Oncotype DX score 19; RSClin recurrence risk 19%; isolated tumor cells around 1 sentinel lymph node without invasion

As of July 2024, Jessica had completed bilateral mastectomy for Stage IB ILC and was moving forward with radiation and long-term hormone suppression after chemotherapy was not recommended.

Lobular Breast Cancer AllianceRead more →

Rare acinic cell breast cancer treated with mastectomy

Patient Info: Anonymized, Female, Under 40

Biomarkers: Triple-negative; pMMR/MSS; Ki-67 very high. TP53 and several other mutations reported; no gene fusion/rearrangement found.

Alive for 43 months with no metastasis or recurrence after surgery, 8 cycles of epirubicin/cyclophosphamide, and radiotherapy for breast acinic cell carcinoma with high-grade solid transformation.

PubMed CentralRead more →

Stage IV Breast Cancer: Samantha's Patient Story

Patient Info: Samantha, Female, Under 40 | Stage IV

Biomarkers: Hormone-positive breast cancer; specific receptor details not reported

Metastatic Site: bone: rib, spine, pelvis

As of July 2024, Samantha was living with Stage IV hormone-positive breast cancer with bone metastases. Current treatment was working in most areas, but a breast tumor continued to grow and was surgically removed; ongoing treatment and 3-month scans were reported.

YouTube — The Patient StoryRead more →

Finding A Lump To BREAST CANCER!

Patient Info: Kelsey Harrison, Female, Under 40 | Stage II

Biomarkers: ER-positive

As of July 2024, Kelsey had completed chemotherapy, double mastectomy with axillary lymph-node removal, and radiation, and was continuing tamoxifen plus Lupron ovarian suppression with additional planned systemic therapy.

The Patient StoryRead more →

HR-Positive Breast Cancer: LaShae's Patient Story

Patient Info: LaShae, Female, Under 40

Biomarkers: ER-positive; MammaPrint high-risk recurrence; 70-gene hereditary cancer panel negative

As of June 2024, LaShae had completed mastectomy and was undergoing TC chemotherapy, with radiation and long-term hormonal therapy planned; no remission or NED status was stated.

The Patient StoryRead more →

Stage II Invasive Lobular Carcinoma: Lizzie's Survivor Story

Patient Info: Lizzie, Female | Stage II

Lizzie completed mastectomy, reconstruction-related surgery and 5 weeks of radiation. She remained on a planned 10-year course of an aromatase inhibitor and became active in breast cancer research advocacy.

Lobular Breast Cancer AllianceRead more →

Stage IV triple-negative breast cancer in remission: CBD and exercise for neuropathy

Patient Info: Anonymized, Female, 50s | Stage IV

Biomarkers: Triple-negative breast cancer. Blood and immune inflammation measures were tracked during neuropathy care.

Metastatic Site: liver

She was in remission for more than 5 years after Stage IV breast cancer with a solitary liver metastasis, while later managing chemotherapy-induced peripheral neuropathy with CBD and an exercise program that improved symptoms and function.

PubMed CentralRead more →

Stage 0 Invasive Ductal Carcinoma: Erica's Survivor Story

Patient Info: Erica Newbert Campbell, Female | Stage 0

Biomarkers: BRCA1/2-negative

As of June 2024, about 6 years after Stage 0 DCIS diagnosis, Erica described her body and mind as cancer-free after double mastectomy and reconstruction.

The Patient StoryRead more →

Stage III HR-Positive Invasive Lobular Carcinoma: Liz's Patient Story

Patient Info: Liz O'Riordan, Female, 40s | Stage III

Biomarkers: ER-positive; HER2-negative; PIK3CA mutation reported by patient

As of June 2024, Liz described Stage III ER-positive/HER2-negative mixed ductal and lobular breast cancer followed by 2 locoregional recurrences after mastectomy; no distant metastatic disease was described for her personal story.

YouTube — Dr Liz O'RiordanRead more →

Breast Cancer and a Rare Benign Blood-Vessel Growth Found in the Same Lymph Node

Patient Info: Anonymized, Female, 40s

Biomarkers: HER2-negative

A 47-year-old woman with hormone receptor-positive, HER2-negative breast cancer had five involved axillary lymph nodes, including one that also contained a rare benign hemangioma.

PubMed CentralRead more →

Secretory Breast Carcinoma With Apocrine Differentiation in a 72-Year-Old Woman

Patient Info: Anonymized, female, 70+

Biomarkers: ER and PR positive in the microcystic component and negative in the solid component; AR-positive in the solid component

More than 1 year after diagnosis, she was alive and under long-term surveillance after surgery.

PubMed CentralRead more →

Primary breast angiosarcoma: R0 resection, disease-free at 6 months

Patient Info: Anonymized, Female, Under 40

Biomarkers: ERG-positive; Ki-67 50%

Disease-free 6 months after skin-sparing mastectomy with R0 resection for localized primary breast angiosarcoma; continued close 3-month surveillance after declining further treatment.

PubMed CentralRead more →