Small hormone-receptor-positive breast cancer found incidentally on chest CT
This breast cancer diagnosis at a glance
- Subtype
- Invasive Ductal Carcinoma
- Biomarkers
- ER 95% positive; PR 70% positive; HER2 negative; Ki-67 11–50%; p53 negative for overexpression
- Sex
- Female
- Treatment
- surgery and radiation
- Outcome
- Care Ongoing
Treatment course, step by step
- Underwent right partial mastectomy and sentinel lymph node biopsy, with clear margins and 0/6 nodes involved.
- Started adjuvant breast radiation therapy.
- Anastrozole 1 mg daily was planned for at least 5 years after radiation.
What happened, in summary
A 76-year-old woman had no breast symptoms when a 0.9 cm right breast nodule was noticed incidentally on a chest CT performed for bronchiectasis. Mammography and ultrasound confirmed a complex solid and cystic mass measuring 1.1 × 0.9 × 1.1 cm.
Core biopsy showed invasive ductal carcinoma, grade 2, with mucinous features. The tumour was 95% estrogen-receptor positive and 70% progesterone-receptor positive, HER2 negative, with a Ki-67 index of 11–50%. The largest tumour focus in a biopsy core measured 0.5 cm.
She underwent needle localization, right partial mastectomy and sentinel lymph-node biopsy. The surgical specimen showed a 0.7 × 0.4 cm moderately differentiated invasive ductal carcinoma with mucinous features. Margins were clear, with the closest margin 0.3 cm away, and all 6 sampled lymph nodes were negative.
At the latest point described, she was receiving adjuvant radiation therapy to the breast. A course of anastrozole 1 mg daily for at least 5 years was planned after radiation.
Where this story comes from
This is a lay summary of an account first published by PMC / PubMed Central. Read the original in full
How we source and attribute stories Accuracy and limitations
Collections this story belongs to
- ER Positive Breast Cancer 242 stories
- Anastrozole for Breast Cancer 71 stories
These are lay summaries of published cancer stories, for information only. No two cancers behave the same way, and nothing here predicts your own diagnosis or replaces advice from your oncology team. Read the full disclaimer