Stage III Breast Cancer: Carole's Survivor Story

Patient Info: Carole, Female, 60s | Stage III

Carole was diagnosed with Stage III breast cancer in 2019 and was declared cancer-free at the end of 2023 after a treatment plan involving surgery, chemotherapy, radiation therapy, and hormonal therapy.

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Stage II HR-Positive Breast Cancer: Cath's Survivor Story

Patient Info: Cath, Female, 60s | Stage II

Biomarkers: ER-positive; PR-positive; HER2-negative

Cath was declared cancer-free in June 2024 after Stage II luminal A ER-positive/PR-positive/HER2-negative breast cancer treated with surgery, radiation, and hormone therapy, though she continued to manage long-term side effects and recurrence fear.

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Stage IV Breast Cancer: Magnolia's Survivor Story

Patient Info: Magnolia | Stage IV

Magnolia was declared cancer-free in March 2022 and described herself as remaining in remission while continuing hormone therapy.

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Stage II Breast Cancer: Emma's Patient Story

Patient Info: Emma, Female, 40s | Stage II

As of 2019, Emma had completed active treatment for Stage II breast cancer after mastectomy, lymphadenectomy, chemotherapy, and hormone therapy, and she remained on hormone therapy.

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Stage II Breast Cancer: Eliza's Patient Story

Patient Info: Eliza | Stage II

Eliza continued to live with fear of recurrence after lumpectomy, radiation therapy, and hormone therapy caused fatigue, inflamed skin, and joint and bone pain.

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Ana's Stage 2 Breast Cancer Treatment and Recovery Story

Patient Info: Ana, Female, 40s | Stage II

Years after diagnosis, Ana had completed chemotherapy, mastectomy, radiation and reconstruction and was continuing hormone therapy with anastrozole. She described herself as optimistic and grateful.

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Stage I Breast Cancer: Aura's Patient Story

Patient Info: Aura, Female, 40s | Stage I

Aura completed mastectomy, lymphadenectomy, hysterectomy, and chemotherapy for Stage I breast cancer and remained on hormone therapy, with ongoing concerns but no documented recurrence or progression.

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Splenectomy Reduced Transfusion Needs in Metastatic Lobular Breast Cancer

Patient Info: Anonymized, Female, 40s | Stage Metastatic/Advanced

Biomarkers: ER positive; PR positive; HER2 negative

Metastatic Site: skin|bone|bone marrow|spleen

She remained independent through her last oncology visit 18 months after splenectomy and died 1 month later.

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Metastatic Breast Cancer Causing Severe Shoulder and Arm Pain

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Metastatic Site: bone

Progressive nodal disease caused disabling brachial-plexus pain. She died about 3 months after placement of the intrathecal pain catheter.

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Breast Cancer: Ken's Survivor Story

Patient Info: Ken Gremling, Male, 70+

Ken's mastectomy removed all of the cancer, and his clinicians expected a full recovery while he continued tamoxifen.

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Breast Cancer: Jane's Survivor Story

Patient Info: Jane Gremling, Female, 60s

Jane's mastectomy removed all of the cancer, and her clinicians expected a full recovery while she continued tamoxifen and prepared for reconstruction.

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Breast Cancer Recurring 18 Years After Mastectomy

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: sternum|lungs|pleura|chest wall

She died during respiratory decline caused by both metastatic breast cancer in the lungs and a separate primary lung cancer.

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Lobular Breast Cancer Spreading to an Eye Muscle

Patient Info: Anonymized, Female, 40s | Stage Metastatic/Advanced

Biomarkers: Hormone receptor-positive; HER2-negative; E-cadherin-negative; CK7-positive

Metastatic Site: bones|left superior oblique eye muscle

The eye-muscle metastasis entered complete local remission, while bone disease was stable after 6 months of weekly paclitaxel and denosumab.

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Recurrent Breast Cancer Initially Mistaken for Organising Pneumonia

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Biomarkers: ER-positive and GATA3-positive atypical pleural-fluid cells

Metastatic Site: lungs

After 12 months of first-line hormone therapy for metastatic recurrence, she had significant clinical and radiological improvement and remained on treatment.

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Breast cancer recurrence involving the bladder and bones

Patient Info: Anonymized, Female | Stage IV

Biomarkers: Initial breast cancer: ER-positive, PR-positive, HER2-negative. Bladder metastasis: ER-positive, PR-negative, HER2 1+.

Metastatic Site: bladder, bone, rectosigmoid region, anorectal region

She died in October 2016 from pulmonary haemorrhage, 47 months after metastatic disease was diagnosed.

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Breast cancer treatment alongside severe pemphigus vulgaris

Patient Info: Anonymized, Female, 50s

Breast-cancer endocrine treatment was ongoing while her pemphigus required a separate treatment strategy; she was followed for 18 months.

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Breast cancer spreading to the colon, rectum and peritoneal surfaces

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: Primary tumor: ER >80% positive; PR 50–60% positive; HER2 negative; E-cadherin positive. Later colorectal metastases: ER positive; PR negative; HER2 negative; CK7 positive; CK20 negative; CDX2 negative.

Metastatic Site: colon, rectum, peritoneum, diaphragm, liver, bowel,…

Metastatic breast cancer was subsequently confirmed in the colon and rectum, with later laparoscopic biopsies showing peritoneal and additional intra-abdominal metastatic disease.

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Breast cancer recurrence presenting with numb chin syndrome

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: sternum, left mandibular foramen

She was discharged ambulatory without lower-limb pain, although left mandibular numbness persisted, with monthly oncology follow-up planned.

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Occult lobular breast cancer presenting as an orbital metastasis

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: ER positive; PR positive; HER2 negative; CK7 positive; CK CAM5.2 positive; E-cadherin negative

Metastatic Site: left orbit, bone

The orbital metastasis decreased with treatment and systemic disease remained controlled on hormonal therapy during 5 years of clinical follow-up.

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Metastatic Breast Cancer With Brain, Bone, Lung and Liver Disease Responding During Eribulin Treatment

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: Initial tumor: ER 90%, HER2 negative, Ki67 10%. Lung metastasis: ER 90%

Metastatic Site: lung, bone, brain, liver

Eribulin remained ongoing with reduced brain lesions, stable bone disease and continued shrinkage of liver metastases after prior systemic progression.

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Stage I Breast Cancer: Yanzi's Patient Story

Patient Info: Yanzi, 40s | Stage I

Years after her Stage I diagnosis, Yanzi had completed the other treatment and remained on hormone medication while coping with fear of recurrence.

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Stage II Breast Cancer: Ana's Survivor Story

Patient Info: Ana, Female, 50s | Stage II

Ana reported being declared cancer-free in March 2020 and continued hormone therapy afterward, with no recurrence described in the available story.

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Metastatic Breast Cancer With Liver Progression Treated Through Multiple Chemotherapy Lines

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: Initial tumor: ER 90%, HER2 3+, Ki67 15%. Liver metastasis: ER 30%

Metastatic Site: pleura, liver

After several periods of response and later liver progression, she remained on active treatment with pegylated liposomal doxorubicin.

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Metastatic Lobular Breast Cancer With Long-Term Disease Control Across Multiple Therapies

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: Initial tumor: ER negative, HER2 negative, Ki67 17%. 2006 recurrence: ER 40%

Metastatic Site: pleura, liver, skin, bone

She was alive on ongoing metronomic vinorelbine with substantial disease stabilization at the most recent follow-up.

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