Stage II HR-Positive Breast Cancer: Cath's Survivor Story

This breast cancer diagnosis at a glance

Stage at diagnosis
Stage II
Biomarkers
ER-positive; PR-positive; HER2-negative
Sex
Female
Treatment
surgery, radiation and hormone therapy
Outcome
Cancer-Free / NED

Treatment course, step by step

  1. Breast surgery
  2. 15 doses of radiation therapy
  3. Tamoxifen as hormone therapy; total hysterectomy and bilateral oophorectomy in 2022 after Tamoxifen-related endometrial hyperplasia with atypical cells
  4. hormone therapy changed to Letrozole.

What happened, in summary

Cath, 63, was diagnosed with Stage II luminal A breast cancer in May 2019 after a routine 2-yearly mammogram led to more imaging and a biopsy. She had no symptoms, and the cancer was described as ER-positive, PR-positive, and HER2-negative. At first she felt optimistic because she was told the cancer was small, but the treatment path became more complicated than expected. Cath had breast surgery first, followed by 15 doses of radiation therapy and 5 years of hormone therapy. She started with Tamoxifen, but it caused endometrial hyperplasia with atypical cells, so in 2022 she had a total hysterectomy and bilateral oophorectomy. Her hormone therapy was then changed to Letrozole. She did not have breast reconstruction because the change in breast shape was minimal. Treatment brought radiation burn, fatigue, and at least 30 hot flushes a day. Effexor and other medication did not relieve them well, and the side effects disrupted sleep and daily life. Cath also faced financial pressure, job changes, permanent loss of work, and a heart condition found during follow-up that required aortic valve replacement and repair of an ascending aortic aneurysm in 2020. She was declared cancer-free in June 2024, but fear of recurrence, chronic pain, and the need to rebuild a new normal remained central parts of her survivorship.

Where this story comes from

This is a lay summary of an account first published by Our Cancer Stories. Read the original in full

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