Rare Ovarian Neuroendocrine Cancer Treated With Surgery and Chemotherapy

Patient Info: Anonymized, female, 40s

Biomarkers: somatic BRCA2 mutation; MSI-H; high tumor mutational burden; germline BRCA2 negative

CT imaging and CA-125 follow-up showed no evidence of recurrence over 2 years.

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Stage III Ovarian Cancer: Shelly's Patient Story

Patient Info: Shelly Sepulveda, Female, 40s | Stage III

Living with recurrent ovarian cancer and receiving weekly intravenous chemotherapy after a brief remission.

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Stage III Ovarian Cancer: Mary's Survivor Story

Patient Info: Mary Catherine Riley, Female, 40s | Stage III

After a 2023 recurrence, Mary achieved a complete response within 1 year on avutometinib and defactinib. She continues the approved combination with quarterly CT scans and monthly labs and has no evidence of disease.

Ovarian cancer treated with chemotherapy and repeat pelvic surgery after recurrence

Patient Info: Anonymized, Female, Under 40

She improved after the repeat pelvic surgery and postoperative care and was discharged home.

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Ovarian Cancer: Angela's Survivor Story

Patient Info: Angela Hernandez, Under 40

By February 2025, she had been cancer-free for 6 years and remained connected to post-cancer care and support.

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Advanced high-grade serous ovarian cancer with treatment-resistant progression and hyperprolactinemia

Patient Info: Anonymized, Female, 50s

Biomarkers: BRCA1 variant of uncertain significance

The ovarian cancer continued to progress despite multiple treatments, and she died 2.5 years after the ovarian-cancer diagnosis.

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Small Cell Ovarian Cancer Causing Acute Kidney Injury

Patient Info: Anonymized, Female | Stage III

Biomarkers: Somatic SMARCA4 alterations; no germline SMARCA4 pathogenic variant

Combined pembrolizumab, carboplatin, and paclitaxel was continued after marked radiologic improvement, with an excellent PET-CT response documented after 13 cycles.

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Stage III BRCA1 Ovarian Cancer: Carla's Survivor Story

Patient Info: Carla Peoples, female | Stage III

Biomarkers: BRCA1 mutation

She was cancer-free after surgery and 6 rounds of chemotherapy and continued olaparib maintenance with CA-125 blood testing every 3 weeks.

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Ovarian Cancer: Lissa's Survivor Story

Patient Info: Lissa Fancher

At the latest update, the patient had no evidence of disease, tumor markers had dropped significantly, and daily hormone therapy was being used to reduce recurrence risk.

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Ovarian Cancer: Shraddha's Patient Story

Patient Info: Shraddha Pandey

Ten years after diagnosis, Shraddha described herself as an ovarian cancer survivor and an advocate for cancer awareness.

Fertility-Sparing Treatment for Ovarian Immature Teratoma in a Young Woman

Patient Info: Anonymized, Female | Stage I

After fertility-sparing surgery, she remained disease-free under surveillance and later conceived naturally, completing a healthy term pregnancy.

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Ovarian Cancer Spreads to the Breast During Platinum-Resistant Recurrence

Patient Info: Anonymized, female, 50s | Stage IV

Biomarkers: BRCA1/2-negative; HRD-positive; PD-L1-positive; folate receptor alpha-positive

Metastatic Site: right breast, right axillary lymph nodes, cervical…

She remained alive with stable disease about 2 years after the breast metastasis was diagnosed while receiving seventh-line mirvetuximab-soravtansine.

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Stage IV Ovarian Cancer: Susan's Patient Story

Patient Info: Susan Dunwoody, female | Stage IV

Susan lived for 7 years after her Stage IV ovarian cancer diagnosis and later died from the disease.

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BRCA1-Mutated Ovarian Cancer Responding to Niraparib After Olaparib Progression

Patient Info: Anonymized, Female, 60s

Biomarkers: Germline BRCA1 pathogenic variant c.188T>A; CA-125 4

Two months after starting niraparib, imaging showed a partial response and CA-125 normalized. At 15 months, she had achieved a complete response and remained progression-free while niraparib continued.

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Ovarian Cancer: Chen's Survivor Story

Patient Info: Chen Wen Ye, Under 40

Nearly 5 years after diagnosis, Chen was cancer-free and attending regular follow-up while volunteering to support other young patients.

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Ovarian cancer chemotherapy continued after paclitaxel-related liver injury

Patient Info: Anonymized, Female, 50s | Stage II

Biomarkers: somatic BRCA1/2 negative

She completed all 6 planned chemotherapy cycles after dose reduction for liver toxicity and then entered routine surveillance.

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Metastatic Ovarian Cancer Presenting With Painful Finger Ischemia

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Biomarkers: CA-125: 90.6 kU/L after 4 cycles of chemotherapy

Metastatic Site: peritoneum|omentum

She continued chemotherapy and palliative symptom management after debulking surgery. She died from an intracranial hemorrhage 10 months after her original presentation.

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Stage IV Ovarian Cancer: Melbey's Patient Story

Patient Info: Melbey Segovia, Female | Stage IV

Melbey Segovia died on May 4, 2021, about 5 years and 3 months after her February 2016 diagnosis, after three relapses and hospice care.

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Stage III Ovarian Cancer: Jaclyn's Patient Story

Patient Info: Jaclyn (Jackie) VanRaaphorst | Stage III

Biomarkers: FRα-positive; CA-125 monitored

AACR later reported that Jackie died on January 16, 2025.

Ovarian Cancer: Jennifer's Patient Story

Patient Info: Jennifer Thorn, Female, 40s

Living with ovarian cancer and continuing gemcitabine after about 2 years of treatment.

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Stage I BRCA1 Ovarian Cancer: Carol's Survivor Story

Patient Info: Carol Arnhart | Stage I

Biomarkers: BRCA1 mutation

After staging surgery and 6 rounds of carboplatin and paclitaxel, she reported no evidence of ovarian cancer.

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Stage I Ovarian Cancer: Elle's Patient Story

Patient Info: Elle Simone Scott, Female, Under 40 | Stage I

Living with recurrent ovarian cancer for more than 6 years after her September 2016 diagnosis, with an active clinical trial slowing progression at the May 2023 publication.

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Stage IV Ovarian Cancer Complicated by Anti-Yo Cerebellar Degeneration

Patient Info: Anonymized, Female | Stage IV

Biomarkers: CA-125: 1767 kU/L; anti-Yo antibodies positive in serum and cerebrospinal fluid

Her anti-Yo paraneoplastic cerebellar degeneration progressed despite methylprednisolone and plasma exchange. Care became palliative, and she died 2 months after hospital admission.

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Stage III Ovarian Cancer: Karoline's Patient Story

Patient Info: Karoline Strauss, female | Stage III

After resuming etigilimab and nivolumab, the patient felt markedly better; by the eighth infusion, some tumors had disappeared and others were shrinking, and treatment was continuing.

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