Stage IIIC Ovarian Cancer Found During Preoperative Screening

Patient Info: Anonymized, Female | Stage III

Biomarkers: BRCA1 pathogenic variant on homologous recombination deficiency testing; germline BRCA1 pathogenic variant

At approximately 1 year after surgery, she was alive without evidence of recurrence while continuing olaparib and bevacizumab maintenance therapy.

PubMed CentralRead more →

Growing Masses After Chemotherapy for an Ovarian Germ Cell Tumor

Patient Info: Anonymized, Female, Under 40

Biomarkers: AFP 581.2 ng/mL and CA-125 74.3 U/mL after surgery

Despite 6 chemotherapy cycles and normalization of AFP, abdominal and pelvic masses continued to grow while CA-125 and CEA increased. She sought a second opinion and underwent imaging and biopsy of an abdominal mass.

PubMed CentralRead more →

Recurrent Malignant Ovarian Steroid Cell Tumor Treated With Multiple Therapies

Patient Info: Anonymized, Female

Biomarkers: PIK3CA, and ATM mutations; ER negative; PR negative

She experienced repeated pelvic and lung recurrences. Platinum-based treatment produced a complete PET-CT response and olaparib maintenance provided about 1 year without progression before a 5 mm lung recurrence was surgically removed.

PubMed CentralRead more →

Stage III Ovarian Cancer During Care for Common Variable Immunodeficiency

Patient Info: Anonymized, Female | Stage III

She remained alive on maintenance bevacizumab, with no radiologic evidence of ovarian-cancer progression.

PubMed CentralRead more →

Stage IIIC Primary Ovarian Leiomyosarcoma Treated With Debulking Surgery and Chemotherapy

Patient Info: Anonymized, Female | Stage III

Biomarkers: SMA positive; caldesmon positive; Ki-67 15%–20%; p53 negative

She recovered from extensive cytoreductive surgery, reported resolution of her symptoms, and began planned adjuvant Adriamycin and ifosfamide.

PubMed CentralRead more →

Stage III BRCA Ovarian Cancer: Mimi's Survivor Story

Patient Info: Mimi Gallagher, 40s | Stage III

Biomarkers: BRCA-positive

Mimi was cancer-free after surgery and 4 months of intraperitoneal chemotherapy, completed in December 2012.

Dana-FarberRead more →

Ovarian Cancer Can Present Unique Challenges Around Gender

Patient Info: Anonymized, 40s

At annual follow-up, the ovarian cancer remained in remission with no recurrences since treatment ended in December 2009.

Dana-FarberRead more →

Ovarian Cancer: Faye's Patient Story

Patient Info: Faye Belvin, Female

Faye was still receiving the trial combination and said the treatment was working and that she felt better than she had in the previous 2 years.

Recurrent Ovarian Cancer and Olaparib-Related Skin Toxicity

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|liver

The latest chemotherapy was effective, and she was alive without signs of another recurrence at the last documented follow-up.

PubMed CentralRead more →

Stage III Ovarian Cancer: Karen's Survivor Story

Patient Info: Karen Howley LaCamera, 50s | Stage III

The REGN4018 clinical trial put Karen’s ovarian cancer into remission, which had lasted nearly a year when the story was written, with follow-up every 6 weeks.

Dana-FarberRead more →

BRCA1 Ovarian Cancer: Mary's Patient Story

Patient Info: Mary Anne Marshall, female

Biomarkers: BRCA1 mutation

She completed a difficult 2-year ovarian cancer treatment course and was alive 4 years into her combined cancer journey.

MD AndersonRead more →

Ovarian Cancer Metastasis to the Cervical Spinal Canal

Patient Info: Anonymized, Female, 70+ | Stage Metastatic/Advanced

Metastatic Site: brain|cervical intradural extramedullary space

Her neck and shoulder pain resolved after spinal surgery, but she developed recurrent brain disease and died from cachexia 4 months after the spinal operation.

PubMed CentralRead more →

Stage IV ovarian cancer complicated by a spontaneous vaginal fistula

Patient Info: Anonymized, Female, 50s | Stage IV

After postoperative chemotherapy, she was clinically well and imaging showed no visible tumor during 8 months of follow-up.

PubMed CentralRead more →

Ovarian Granulosa Cell Tumor Recurring 17 Years After Surgery

Patient Info: Anonymized, Female, 70+

Biomarkers: Weak oestrogen sensitivity

Complete resection was not possible, but debulking relieved pressure on surrounding structures and improved her quality of life. She then continued oncology care with palliative carboplatin and paclitaxel.

PubMed CentralRead more →

Metastatic Clear Cell Ovarian Cancer Complicated by Treatment-Related Sarcoidosis

Patient Info: Anonymized, Female, 60s | Stage Metastatic/Advanced

Metastatic Site: peritoneum

During a treatment holiday, biopsy and laboratory evaluation showed treatment-related sarcoidosis rather than ovarian-cancer spread in the enlarged lymph nodes. After prednisone, the sarcoidosis resolved and imaging showed no progression of the clear cell ovarian cancer; she remained clinically well 4 months later.

PubMed CentralRead more →

BRCA Ovarian Cancer: Christie's Patient Story

Patient Info: Christie Siebel, female

Biomarkers: BRCA mutation

At the latest update, Christie was doing well and having a CA125 blood test every 3 months for ovarian cancer follow-up.

MD AndersonRead more →

Immature Ovarian Teratoma Followed by Anti-NMDAR Encephalitis

Patient Info: Anonymized, Female

Biomarkers: AFP 67.6 ng/mL; CA-125 89 at presentation

After 4 cycles of chemotherapy, her neurological deficits fully recovered and she could walk independently, with mild stuttering improving through speech therapy.

PubMed CentralRead more →

Ovarian Cancer: Shelley's Patient Story

Patient Info: Shelley O’Keefe, female

Shelley was nearing the end of chemotherapy, rebuilding her strength, and returning to demanding golf activity with strong family and community support.

Ovarian Cancer: Dana's Patient Story

Patient Info: Dana Kivel, female

Dana was living with recurrent, metastatic granulosa cell ovarian cancer and taking an aromatase inhibitor for a current tumor.

Stage 4 Ovarian Cancer Discovered During Trigeminal Neuralgia Evaluation

Patient Info: Anonymized, Female, 50s | Stage IV

Three months after surgery, she had recovered well from debulking and 6 total chemotherapy cycles, with complete macroscopic clearance achieved at surgery. Trigeminal-neuralgia symptoms persisted and continued to require daily medication.

PubMed CentralRead more →

Kidney Complications After Treatment for Stage IV Ovarian Cancer

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: peritoneum|left lymph node

No further ovarian-cancer progression was observed during the 10 months after kidney biopsy. The nephrotic syndrome reached partial remission after immunosuppressive treatment was stopped and supportive care continued.

PubMed CentralRead more →

Aggressive Presumed Ovarian Solid Pseudopapillary Tumor With Widespread Metastases

Patient Info: Anonymized, Female | Stage Metastatic/Advanced

Metastatic Site: peritoneum|pelvic soft tissue|inguinal lymph…

The disease progressed rapidly across multiple abdominal and nodal sites. She died from disease-related complications 2 months after the oncology consultation while receiving induction chemotherapy.

PubMed CentralRead more →

Ovarian Cancer: Lauren's Survivor Story

Patient Info: Lauren Wells, Female, Under 40

Lauren was described as cancer-free and making a strong recovery while continuing physical, occupational, and speech therapy.

Cleveland ClinicRead more →

Ovarian Cancer: Elle's Patient Story

Patient Info: Elle Simone, female

Elle was dealing with an ovarian cancer recurrence while continuing her work and advocacy.