Cancer Stories
Lung CancerStage III ROS1 Non-Small Cell Lung Cancer: Wendy's Survivor Story
Patient Info: Wendy, Female | Stage III
Biomarkers: ROS1-positive / ROS1-rearranged
Lung CancerPatient Info: Anonymized, Male, 60s | Stage IV
Biomarkers: PD-L1 about 1%; KRAS mutation
Metastatic Site: bone (right 4th and 5th ribs)
Lung CancerPatient Info: Anonymized, Male, 50s
Biomarkers: No molecular biomarkers reported for SCLC. Bladder biopsy during cystitis showed mostly CD3/CD8-positive T-cell inflammation.
Lung CancerPatient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: PD-L1-high lung adenocarcinoma with EGFR/ALK/ROS1 wild type and TTF-1 positive. KLHL11-IgG was linked to cerebellitis.
Metastatic Site: M1a disease; specific metastatic site not otherwise…
Lung CancerSmall Cell Lung Cancer: Montessa's Survivor Story
Patient Info: Montessa, Female, Under 40
Lung CancerStage III Non-Small Cell Lung Cancer: Heidi's Survivor Story
Patient Info: Heidi N., Female, 50s | Stage III
Biomarkers: No targetable mutation identified
Lung CancerStage II KRAS Lung Adenocarcinoma: Roy's Survivor Story
Patient Info: Roy, Male, 50s | Stage II
Biomarkers: KRAS
Lung CancerLung cancer treated with tislelizumab: rare fluid buildup around the lung as a side effect
Patient Info: Anonymized, Male, 60s
Lung CancerMore than 5 years of disease control with maintenance chemotherapy for Stage IV lung cancer
Patient Info: Anonymized, Male | Stage IV
Biomarkers: KRAS mutation; TP53 mutation
Metastatic Site: brain
Lung CancerPatient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: PD-L1 20%
Metastatic Site: bilateral lungs
Lung CancerEGFR-mutant lung adenocarcinoma with acquired ROS1 rearrangement after EGFR-TKI resistance
Patient Info: Anonymized, Female, 50s | Stage IV
Biomarkers: EGFR exon 19 deletion; acquired EGFR T790M; acquired EZR exon10-ROS1 exon34 rearrangement
Metastatic Site: bone (distal femur); contralateral lung;…
Lung CancerStage 4 lung cancer: persistent cough led to diagnosis
Patient Info: Anonymized, Male, 60s | Stage IV
Biomarkers: KRAS and TP53 ; PD-L1 TPS 95%. Other common lung drivers were not detected.
Metastatic Site: liver, left adrenal gland, lymph nodes, pleural…
Lung CancerPatient Info: Anonymized, Male | Stage IV
Biomarkers: EGFR L861Q; PD-L1 TPS/CPS 65%. TP53, MET and PIK3CA alterations also reported.
Metastatic Site: left ventricular myocardium; mediastinal lymph nodes…
Lung CancerPatient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: EGFR exon 19 deletion persisted. Later pleural fluid had PD-L1 TPS 40% / CPS 41, low TMB
Metastatic Site: pleura / malignant pleural effusion
Lung CancerPatient Info: Anonymized, Male, 70+ | Stage III
Biomarkers: Ki-67 20-25%; PD-L1 expression 10%; KRAS exon 2 mutation; STK11 mutation; TP53 mutation
Lung CancerPatient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: Lung cancer markers supported adenocarcinoma. PD-L1 negative; no common lung driver found; TMB high; MSI not detected.
Metastatic Site: brain, leptomeningeal disease, left supraclavicular…
Lung CancerStage IV Lung Cancer: Tina's Patient Story
Patient Info: Tina Powell, Female | Stage IV
Lung CancerSecond primary Stage I lung adenocarcinoma treated with segmentectomy and adjuvant pembrolizumab
Patient Info: Anonymized, Female, 70+ | Stage I
Biomarkers: PD-L1 <1%; no common targetable lung cancer changes found in EGFR, ALK, KRAS, BRAF, MET, PIK3CA, RET, ROS1, or NTRK.
Lung CancerPatient Info: Anonymized, Female, 40s | Stage IV
Biomarkers: CEA 62 ng/mL; CA19-9 and neuron-specific enolase within normal limits; no molecular biomarkers reported
Metastatic Site: bone (11th thoracic vertebra)
Lung CancerALK-fusion lung adenocarcinoma with pleural progression: alectinib toxicity and switch to lorlatinib
Patient Info: Anonymized, Male, 50s | Stage IV
Biomarkers: EML4::ALK fusion positive
Metastatic Site: pleura
Lung CancerPatient Info: Anonymized, Male, 70+ | Stage III
Biomarkers: No molecular biomarkers reported
Lung CancerStage III Lung Cancer Treatment Complicated by Adult T-Cell Leukemia/Lymphoma
Patient Info: Anonymized, male, 70+ | Stage III
Lung CancerPatient Info: Anonymized, Female, 70+ | Stage III
Biomarkers: KRAS p.G12V mutation; PD-L1 0% tumor-cell staining; <1% tumor-associated inflammatory-cell staining; no EGFR, ALK, or ROS1 driver mutation reported
Lung CancerStage IIIA lung adenocarcinoma complicated by severe atezolizumab-induced liver toxicity
Patient Info: Anonymized, Male, 60s | Stage III
Biomarkers: PD-L1 49%; case text describes triple-negative status without expanding the specific markers