Stage III colon cancer followed by a second gastro-oesophageal adenocarcinoma

Patient Info: Anonymized, Female | Stage III

Biomarkers: KRAS-mutated, NRAS-negative, BRAF-negative

After surgery and 4 cycles of CAPEOX, imaging initially showed no metastases. Later imaging showed new bilobar liver lesions, and a separate primary gastro-oesophageal adenocarcinoma was diagnosed about 1 year after the colon cancer.

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Stage IV Colorectal Cancer: Kasey's Patient Story

Patient Info: Kasey, Female, Under 40 | Stage IV

Biomarkers: CEA elevated; no genomic biomarker reported

Metastatic Site: liver

Kasey was diagnosed with Stage II colon cancer in February 2024 and progressed to Stage IV disease with a liver lesion in September 2024. As of April 2025, she was continuing chemotherapy after liver surgery.

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Stage III Colorectal Adenocarcinoma: Chloe's Survivor Story

Patient Info: Chloe, Female | Stage III

Biomarkers: Familial adenomatous polyposis

As of April 2025, Chloe was in remission after emergency surgery with a stoma and 4 rounds of IV/oral chemotherapy for Stage III FAP-associated colon adenocarcinoma.

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Cardiac arrest during rectal cancer surgery caused by an anal-cardiac reflex

Patient Info: Anonymized, Male, 50s

The operation was completed after successful resuscitation from two intraoperative cardiac arrests, and he had no related cardiac-arrest sequelae during the following year.

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Stage III Colorectal Cancer: Chloe's Survivor Story

Patient Info: Chloe, Female, Under 40 | Stage III

Biomarkers: Rare genetic disorder/gene reported; exact gene not stated

Chloe was diagnosed with Stage III colon cancer in February 2024 after emergency surgery. After surgery, stoma creation, and 3 months of chemotherapy, she was told she was in remission in June 2024 and remained on surveillance.

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Stage II Colorectal Cancer: Kristin's Survivor Story

Patient Info: Kristin, Female | Stage II

Kristin had Stage II colon cancer treated with emergency surgery and 4 months of chemotherapy. Her February 2022 scan confirmed no evidence of disease, and as of March 2025 she had recently celebrated 3 years cancer-free.

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Mark: Stage III Colorectal Cancer

Patient Info: Mark, Male, Under 40 | Stage III

Biomarkers: Lynch syndrome negative

As of March 2025, Mark was sharing his story after surgery and intensive chemotherapy for Stage IIIB colon cancer and had been declared to have no evidence of disease in 2021.

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Stage III Colorectal Cancer: Courtney's Survivor Story

Patient Info: Courtney Vigars, Female, Under 40 | Stage III

In her fifth year of remission at the time of the 2025 story after transanal surgery, radiation, and chemotherapy for Stage III rectal cancer; she had returned to an active working life.

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Stage IV Colorectal Cancer: Bill's Patient Story

Patient Info: Bill, Male, 40s | Stage IV

Metastatic Site: Liver | Lungs | Brain

As of March 2025, Bill was living with incurable Stage IV colon cancer after liver, lung, and brain involvement, with ongoing chemotherapy and lifelong maintenance treatment.

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Stage III Colorectal Cancer: Mark's Survivor Story

Patient Info: Mark, Male, Under 40 | Stage III

Biomarkers: Tumor genetic testing negative; Lynch syndrome not detected

Mark had Stage III right-sided colon cancer treated with surgery and chemotherapy. He has been considered no evidence of disease since finishing chemotherapy in spring 2021 and had passed the 4-year post-surgery milestone as of March 2025.

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Stage III Colorectal Cancer: Heather's Survivor Story

Patient Info: Heather Russell, Female, Under 40 | Stage III

In her fifth year of remission at the time of the 2025 story after treatment for Stage III rectal cancer; she had returned to family and working life, with some lasting treatment effects.

Cleveland ClinicRead more →

Stage IV KRAS Colorectal Cancer: Bill's Patient Story

Patient Info: Bill, Male, 40s | Stage IV

Biomarkers: KRAS mutation

Metastatic Site: liver; lung; brain

Bill has Stage IV KRAS G12A-mutated colon cancer with liver, lung, and brain metastases. After multiple surgeries, ablation, Gamma Knife, and repeated chemotherapy, tumors shrank and he moved to lifelong maintenance chemotherapy every 2 weeks as of March 2025.

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Shannin: Stage IV Colorectal Cancer

Patient Info: Shannin, Female, Under 40 | Stage IV

Biomarkers: Tumor-marker testing used to select immunotherapy

Metastatic Site: Liver

As of March 2025, Shannin was living with Stage IV colon cancer with cancer remaining in the liver while receiving chemotherapy and tumor-marker-matched immunotherapy.

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Stage IV Colorectal Cancer: Shannin's Patient Story

Patient Info: Shannin, Female, Under 40 | Stage IV

Biomarkers: Genetic testing negative; tumor-marker match for immunotherapy reported, exact marker not stated

Metastatic Site: liver; ovaries; peritoneum

Shannin has palliative Stage IV metastatic colorectal cancer with liver, ovarian, and peritoneal involvement. As of March 2025, she was continuing chemotherapy plus immunotherapy, had responded enough to keep treatment going, but still needed liver-directed options and did not qualify for a Canadian liver-pump trial.

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Edie: Stage III Colorectal Cancer

Patient Info: Edie, Female, 50s | Stage III

As of March 2025, Edie had recovered after chemotherapy, radiation, lower anterior resection, temporary ileostomy, and reversal; lymph nodes were negative, margins were clean, and follow-up scans and colonoscopies had remained clear.

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Stage III Colorectal Adenocarcinoma: Katie's Survivor Story

Patient Info: Katie, Female | Stage III

Katie completed surgery and chemotherapy for Stage IIIB transverse colon adenocarcinoma. Her ctDNA tests have been negative since surgery, scans have been clean, and treatment ended in summer 2023; as of February 2025, she was in survivorship and follow-up.

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Stage III Colorectal Cancer: Katie's Survivor Story

Patient Info: Katie, Female | Stage III

As of February 2025, Katie had no evidence of disease after surgery and 6 cycles of chemotherapy and was continuing reassuring follow-up, including ctDNA testing.

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Colorectal Cancer: Cattie's Patient Story

Patient Info: Cattie Fleming, Female

Cattie remained on chemotherapy, and her most recent scans showed that treatment was effective.

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Stage III Colorectal Cancer: Edie's Survivor Story

Patient Info: Edie, Female, 50s | Stage III

After total neoadjuvant treatment, lower anterior resection, and ileostomy reversal, Edie reported clear scans/colonoscopies and described herself as a colon cancer survivor. As of February 2025, she remained in survivorship.

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Genetic testing confirms a local recurrence of Stage III sigmoid colon cancer

Patient Info: Anonymized, Male, 50s | Stage III

Biomarkers: KRAS, PIK3CA, BRAF -negative

One year after surgery for the local recurrence, he remained free of both local recurrence and distant metastases.

PubMed CentralRead more →

Stage IV Colorectal Cancer: Evan's Patient Story

Patient Info: Evan White, Male, Under 40 | Stage IV

Metastatic Site: lungs

After 1 year with no evidence of disease, Evan developed colorectal recurrence and later lung metastases; he died in October 2021 after about 4 years with cancer.

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Stage III Colorectal Cancer: Skylee's Survivor Story

Patient Info: Skylee Tinker, Female, 40s | Stage III

Skylee completed surgery and 12 chemotherapy rounds and continued to cope with scan anxiety and survivor guilt; no recurrence or current scan result was reported.

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Stage III Colorectal Cancer: Wendy's Survivor Story

Patient Info: Wendy Harpp, Female, 50s | Stage III

Wendy completed multimodal treatment in 2020 and later became an active colorectal-cancer advocate; current surveillance results and recurrence status were not reported.

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Antonio Dionizio

Patient Info: Anonymized, Male, 60s | Stage III

His son reported that surgery and chemotherapy worked and that he was preparing to celebrate his 84th birthday in 2025, more than 20 years after diagnosis.

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