Colon cancer recurring in the spleen with a serious splenic abscess

Patient Info: Anonymized, Male, 40s | Stage IV

Biomarkers: KRAS wild-type, NRAS wild-type, BRAF wild-type

Metastatic Site: spleen

More than 5 years after his 2016 colectomy, he was treated for metastatic recurrence. Disease was assessed as stable during systemic therapy, and he later recovered well after splenectomy for confirmed splenic metastasis.

PubMed CentralRead more →

Stage III Colorectal Cancer: Jose's Survivor Story

Patient Info: Jose Santos, Male, 40s | Stage III

As of December 2024, more than 2 years after surgery for Stage III colorectal cancer, Jose had no evidence of disease, had adapted well to his ileostomy, and no longer had ulcerative colitis symptoms.

City of HopeRead more →

Stage I Colorectal Cancer: Jay's Survivor Story

Patient Info: Jay Trevino, Male, 40s | Stage I

As of December 2024, Jay had Stage I colon cancer removed completely by laparoscopic surgery, was home within 24 hours, had a very good prognosis, and was planned for periodic blood tests and CT scans.

Cleveland ClinicRead more →

Rare SMARCB1/INI1-deficient undifferentiated carcinoma of the colon

Patient Info: Anonymized, Male, 70+

Biomarkers: KRAS, BRAF wild-type, NRAS wild-type

A 70-year-old man underwent surgery for an unusual aggressive colon carcinoma with loss of SMARCB1/INI1 expression and a KRAS G12D mutation.

PubMed CentralRead more →

Stage IV Colorectal Cancer: Monica's Patient Story

Patient Info: Monica, Female, Under 40 | Stage IV

Metastatic Site: lymph nodes

As of November 2024, Monica was still in active treatment, but lymph nodes had shrunk after chemotherapy and further surgery plus additional chemotherapy were planned.

The Patient StoryRead more →

Rectal cancer surgery in a man with situs inversus and prior major stroke

Patient Info: Anonymized, Male, 60s

He recovered from surgery and had no tumor recurrence or metastasis during 24 months of follow-up.

PubMed CentralRead more →

Jazz: Stage III / borderline Stage IV colorectal cancer

Patient Info: Jazz, Male | Stage III

As of November 2024, Jazz was in active treatment for Stage III / borderline Stage IV colorectal cancer after colostomy surgery, chemotherapy, stomach tumor removal, and radiation, with surgery still planned for the remaining tumor.

The Patient StoryRead more →

Stage III Colorectal Cancer: Jazz's Patient Story

Patient Info: Jazz Page, Male | Stage III

As of November 2024, Jazz was still in active treatment planning with radiation, oral chemotherapy pills, and final surgery expected; no post-treatment remission status was reported.

The Patient StoryRead more →

Stage IV Colorectal Cancer: Jess's Survivor Story

Patient Info: Jess Thompson, Female, Under 40 | Stage IV

Biomarkers: Genetic mutation reported; exact mutation name unclear in source text

Metastatic Site: lymph nodes, abdominal fat/soft tissue

As of October 2024, Jess reported no evidence of disease since November 2022 and almost 2 years in remission after surgery and 6 months of chemotherapy.

The Patient StoryRead more →

Paul: Stage III Colorectal Cancer

Patient Info: Paul, Male | Stage III

As of October 2024, Paul was in active care for Stage III rectal cancer with CAPOX chemotherapy, planned radiation, and eventual surgery.

The Patient StoryRead more →

Maddee: Stage II Colorectal Cancer

Patient Info: Maddee, Female | Stage II

Biomarkers: Lynch syndrome

As of October 2024, Maddee was in surveillance after surgery for Stage II Lynch syndrome-associated colon cancer, with about 1 foot of colon and 40 lymph nodes removed and no chemotherapy given.

The Patient StoryRead more →

Stage II Colorectal Cancer: Maddee's Survivor Story

Patient Info: Maddee Moore, Female, Under 40 | Stage II

Biomarkers: Lynch syndrome

As of October 2024, Maddee had no reported recurrence after surgery for Stage II colon cancer and remained in close surveillance because of Lynch syndrome.

The Patient StoryRead more →

Stage III Colorectal Cancer: Jessenia's Patient Story

Patient Info: Jessenia, Female, Under 40 | Stage III

As of September 2024, Jessenia had completed major treatment steps and was adapting to the physical and emotional effects of treatment, including a temporary colostomy; a clear remission/NED status was not stated.

The Patient StoryRead more →

Stage IV KRAS Colorectal Cancer: Lauren's Patient Story

Patient Info: Lauren Bimage, Female, Under 40 | Stage IV

Biomarkers: Patient-reported KRAS-mutated colon cancer

Metastatic Site: chest; abdominal/peritoneal lining; spine/back

As of September 2024, Lauren was living with both Stage IV breast cancer and Stage IV colon cancer. Colon cancer markers were described as low/normal, while biopsy showed the persistent back/spine disease was breast cancer.

The Patient StoryRead more →

Stage III Colorectal Cancer: Alicia's Patient Story

Patient Info: Alicia Blakey, Under 40 | Stage III

Alicia was undergoing FOLFOX chemotherapy for Stage III colon cancer through October 2024 after colon surgery in May.

Fight Colorectal CancerRead more →

Young woman with familial adenomatous polyposis and metastatic colorectal cancer

Patient Info: Anonymized, Female, Under 40 | Stage IV

Metastatic Site: left ovary

She completed 12 rounds of FOLFOX and was doing well during ongoing follow-up with imaging and laboratory monitoring.

PubMed CentralRead more →

Stephanie’s Stage 3 Colon Cancer Story

Patient Info: Stephanie, Female, Under 40 | Stage III

CT and PET imaging after treatment showed no active colon cancer. Her October 2023 scans were clear and her oncologist described the cancer as in remission; unchanged spots in the liver and lung continued to be monitored.

The Patient StoryRead more →

Stage 0 Colorectal Cancer: Tracy's Survivor Story

Patient Info: Tracy Robert, Female, 40s | Stage 0

Biomarkers: Chemotherapy metabolism gene variant reported; exact gene not stated

As of August 2024, Tracy was a long-term survivor. After chemoradiation and surgery, pathology showed Stage 0/no remaining cancer, and no recurrence was reported.

The Patient StoryRead more →

Colorectal Cancer: Paula's Survivor Story

Patient Info: Paula Chambers Raney, Female

Biomarkers: Lynch syndrome negative; broad hereditary panel with no genetic markers reported

As of August 2024, Paula was a 9-year colorectal cancer survivor with no recurrence reported after surgery.

The Patient StoryRead more →

Sophie: Stage IV Colorectal Cancer

Patient Info: Sophie, Female | Stage IV

Biomarkers: BRAF mutation; MSI

Metastatic Site: Liver; lymph nodes; other torso lesions

As of August 2024, Sophie had been declared cancer-free after Stage IV BRAF-mutated/MSI bowel cancer responded to nivolumab/ipilimumab-based immunotherapy, with PET imaging and liver surgery biopsy showing no cancerous cells.

The Patient StoryRead more →

Stage IV Colorectal Adenocarcinoma: Nick's Patient Story

Patient Info: Nick Sprague, Male, 40s | Stage IV

Metastatic Site: distant lymph nodes in abdomen/near aorta and left…

As of July 2024, Nick was living with Stage IVA colon cancer and receiving Keytruda/pembrolizumab with fewer side effects than chemotherapy; no NED status had been reached.

The Patient StoryRead more →

Colorectal Cancer: Jay's Patient Story

Patient Info: Jay Reese, Under 40

Biomarkers: Lynch syndrome

After a full colectomy in February 2012, Jay did not need further surgery, radiation, or chemotherapy and continued close surveillance because of Lynch syndrome.

Dana-FarberRead more →

Stage IV Colorectal Adenocarcinoma: Elizabeth's Survivor Story

Patient Info: Elizabeth Wachsberg, Female | Stage IV

Metastatic Site: liver

As of July 2024, Elizabeth was 5 years cancer-free after Stage IV colon cancer with liver metastases, chemotherapy, and surgery.

The Patient StoryRead more →

Sigmoid colon cancer with attenuated adenomatous polyposis and an uncertain MSH6 variant

Patient Info: Anonymized, female, 50s

Biomarkers: Germline MSH6 variant c.3163G>A

A 50-year-old woman with sigmoid colon adenocarcinoma and about 25 colonic polyps underwent total colectomy and was found to carry an uncertain germline MSH6 variant.

PubMed CentralRead more →