Kate Joyal

Patient Info: Kate Joyal | Stage IV

After 8 rounds of chemotherapy and colorectal surgery, Kate reported clear follow-up scans and remained hopeful about becoming cancer-free.

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Stage IV Colorectal Adenocarcinoma: Lauren's Patient Story

Patient Info: Lauren, Female, 40s | Stage IV

Biomarkers: No actionable biomarkers reported; tumor testing suggested Lynch syndrome/hereditary pattern was unlikely; germline genetic testing pending

Lauren had Stage IV signet-ring cell colon cancer diagnosed after obstruction and emergency surgery with colostomy. As of July 2025, she was receiving traditional colorectal chemotherapy and awaiting germline genetic testing; remission was not stated.

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Stage II Colorectal Cancer: Andrea's Patient Story

Patient Info: Andrea Suarez V | Stage II

Nearly 9 years later, Andrea described herself as a survivor and advocate for culturally appropriate colorectal cancer care.

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Stage 4 colorectal cancer: complete response with panitumumab and FOLFOX4

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: KRAS/NRAS/BRAF wild type; MSS/pMMR; HER2 not overexpressed. CEA and CA19-9 were elevated.

Metastatic Site: periaortic and pelvic lymph nodes; left ovary/adnexa

As of November 2024, she was alive and continuing second-line FOLFIRI with stable disease after prior complete remission on panitumumab plus FOLFOX4 and later progression with ovarian metastasis.

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Stage III Colorectal Cancer: Paige's Patient Story

Patient Info: Paige Cipher, Female, Under 40 | Stage III

Paige had Stage III rectal cancer and was still in treatment. After 6 rounds of chemotherapy, the tumor had shrunk but was not gone; as of June 2025, she had just completed round 7, had 1 more round planned, and expected surgery in about 3 weeks.

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Stage III Colorectal Cancer: Jackson's Survivor Story

Patient Info: Jackson, Male, Under 40 | Stage III

Jackson completed surgery and chemotherapy for Stage III colon cancer. After his final infusion on January 28, 2025, Signatera was negative, chest and abdomen CTs were clear, tumor-marker bloodwork was negative, and he was declared in remission/no evidence of disease; a later CT in June 2025 was also clear.

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Colorectal Cancer: Julie's Patient Story

Patient Info: Julie Goodrich

Nearly 2 years after surgery and 12 rounds of chemotherapy, Julie described herself as doing well.

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Stage IV Colorectal Cancer: Jay's Survivor Story

Patient Info: Jay, Male, 40s | Stage IV

Metastatic Site: liver

Jay was diagnosed with Stage IV colon cancer in 2013 with extensive liver metastases. After surgery, systemic chemotherapy, hepatic arterial infusion pump therapy, liver resection, ablations, and prolonged chemotherapy, he became clear by 2016 and later described long-term survivorship.

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Metastatic colorectal cancer treated with chemotherapy, cytoreductive surgery and HIPEC

Patient Info: Anonymized, Female, 40s | Stage IV

Metastatic Site: peritoneum, liver

She recovered sufficiently to be discharged home after cytoreductive surgery with HIPEC despite postoperative bone-marrow suppression, anastomotic dehiscence and pelvic sepsis.

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Metastatic colon cancer: soft-tissue and adrenal metastases responding to FOLFIRI plus bevacizumab

Patient Info: Anonymized, Female, 60s | Stage IV

Biomarkers: KRAS codon 146 mutation; BRAF wild type. CK20 and Ki-67 supported colorectal metastasis; CEA/CA19-9 were elevated.

Metastatic Site: lungs; left arm/biceps soft tissue; right…

As of May 2025, metastatic colon cancer involving soft tissue, muscle, lung history, and right adrenal gland had regressed after 12 months of FOLFIRI plus bevacizumab, and the patient was alive 1 year after chemotherapy completion.

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MSI-H locally advanced right colon cancer: pathologic complete response after oxaliplatin, capecitabine, and immunotherapy

Patient Info: Anonymized, Female, 60s

Biomarkers: MSI-H on tumor gene testing

After oxaliplatin, capecitabine, and sindilizumab conversion therapy followed by laparoscopic radical right hemicolectomy, postoperative pathology showed no viable tumor cells and tumor regression grade 0 complete response.

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Stage III Colorectal Cancer: James's Survivor Story

Patient Info: James, Male | Stage III

James had Stage IIIC / possible Stage IV rectal cancer with major lymph node involvement and an uncertain liver spot. After chemotherapy, radiation, multiple surgeries, permanent colostomy, and adjuvant chemotherapy, he later reported no evidence of disease.

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Metastatic rectal cancer responding well after intensive treatment despite severe chemotherapy complications

Patient Info: Anonymized, Male, 40s | Stage IV

Biomarkers: KRAS exon 4 mutation, BRAF wild-type, PD-L1 CPS 2

Metastatic Site: liver, lung

After more than 14 months of treatment, the primary rectal tumor and most lung metastases had been resected, liver lesions had largely regressed, and he was described as near NED while continuing maintenance capecitabine plus bevacizumab.

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Colorectal Cancer: Crystal's Survivor Story

Patient Info: Crystal, Female

Crystal completed limited chemotherapy and multiple major surgeries for colon cancer complicated by bladder involvement and infection risk. She lost her bladder and adapted to ostomy changes. No explicit NED, recurrence, or active-disease status was given.

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Stage II Colorectal Cancer: Marc's Survivor Story

Patient Info: Marc Anthony, Male, Under 40 | Stage II

Biomarkers: Lynch syndrome

Marc Anthony had Stage IIA colon cancer treated with surgery alone. He did not need chemotherapy or radiation, later learned he had Lynch syndrome, and continued awareness/surveillance because of hereditary risk.

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Stage IV Colorectal Cancer: Esteban's Survivor Story

Patient Info: Esteban Moreno | Stage IV

Biomarkers: Lynch syndrome

After immunotherapy and surgery for Stage IV colorectal cancer, Esteban reported recent scans showing no signs of cancer and described himself as NED.

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Stage IV Colorectal Cancer: Crystal's Survivor Story

Patient Info: Crystal, Female | Stage IV

Metastatic Site: Bladder involvement

As of May 2025, Crystal was living after major surgery for Stage IV colon cancer involving the bladder, with both colostomy and urostomy bags and an emphasis on mental health, support, and quality of life.

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Metastatic Colorectal Cancer With NRG1 Fusion Controlled for Years With Afatinib

Patient Info: Anonymized, female, 40s | Stage IV

Biomarkers: MATN-NRG1 fusion; no KRAS alteration detected

Afatinib controlled her metastatic colorectal cancer for 136 weeks. After resection of the remaining target lesion in September 2022, she remained alive with no progression as of October 2024.

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Stage IV Colorectal Cancer: Albita's Patient Story

Patient Info: Albita, Female, Under 40 | Stage IV

Biomarkers: Described as wild type; no hereditary genetic marker reported

Metastatic Site: liver

Albita had Stage IV colon cancer with liver metastases. As of April 2025, the only active cancer she described was still in the liver, with 3 spots remaining after chemotherapy, radiation, liver resection, hysterectomy/colon surgery, ileostomy, and ongoing/planned liver-directed treatment.

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Rectal cancer recurring years later with perineural spread and distant metastases

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: brain, lung, bone

Despite further chemotherapy, the cancer progressed to the brain, lungs and bones, and she died about 1 year later, approximately 9 years after her initial rectal-cancer treatment.

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Stage I Colorectal Cancer: Monica's Survivor Story

Patient Info: Monica Dean, Female, 40s | Stage I

As of April 2025, Monica was disease-free after Stage I colorectal cancer was removed with lower anterior resection; pathology showed clean margins and no lymph node involvement, and she did not need chemotherapy or radiation.

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Lynch syndrome bifocal colon cancer: complete pathological remission after sintilimab

Patient Info: Anonymized, Male, 40s | Stage III

Biomarkers: Lynch-associated colon cancer with MSI-H and KRAS/NRAS/BRAF wild type; tumor markers were low or near normal.

As of April 2025, pathology after proximal colectomy showed tumor regression grade 0 with complete pathological remission, and follow-up found no recurrence or metastasis.

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Stage II Colorectal Cancer: Monica's Survivor Story

Patient Info: Monica Dean, Female, 40s | Stage II

Biomarkers: No genetic predisposition reported after testing

Monica Dean had Stage II colorectal cancer found by screening colonoscopy. Curative surgery showed clear margins and no lymph node involvement, so she did not need chemotherapy or radiation. As of April 2025, she was recovering with a temporary ileostomy and planning reversal.

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Michelle: Stage IV Colorectal Cancer

Patient Info: Michelle, Female, 40s | Stage IV

Metastatic Site: Ovary | Femoral nerve region

As of April 2025, Michelle described living as a Stage IV colorectal cancer survivor after FOLFOX, major surgery, 2.5 years with no evidence of disease, and a later PET-detected recurrence involving the femoral nerve region.

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