Stage IV Colorectal Cancer: Howard's Patient Story

Patient Info: Howard Brown, Male, 50s | Stage IV

Metastatic Site: peritoneum|liver

Howard was living with metastatic colon cancer and undergoing CT scans every 90 days, with further treatment depending on whether scans showed recurrence or progression.

A benign liver granuloma mimicked rectal-cancer recurrence after chemotherapy

Patient Info: Anonymized, Male, 40s

Rectal resection showed a pathologic complete response, and the enlarging liver lesion was repeatedly confirmed as non-malignant granulomatous inflammation rather than metastatic recurrence.

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An unusual paratesticular metastasis from colon cancer

Patient Info: Anonymized, Male, 50s | Stage IV

Biomarkers: CK20-positive; CDX2-positive; CK7-negative.

Metastatic Site: lungs; right paratesticular soft tissue

He recovered well after removal of the paratesticular metastasis and continued treatment for metastatic colon cancer with his oncology team.

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Colorectal Cancer: Mary's Patient Story

Patient Info: Mary

Within 12 months of the initial treatment course, further tumors were found during follow-up, including one in the liver.

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Stage I Colorectal Cancer: Aloysius's Patient Story

Patient Info: Aloysius | Stage I

He is receiving chemotherapy after partial colectomy for Stage I colorectal cancer and remains hopeful about recovery.

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Stage II Colorectal Cancer: Clement's Patient Story

Patient Info: Clement | Stage II

Clement continues to live with colorectal cancer after chemotherapy was stopped because of severe side effects, while focusing on his health and family.

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Stage I Colorectal Cancer: Andy's Survivor Story

Patient Info: Andy | Stage I

Andy describes reaching remission after treatment and continues regular colon screening because of concern about recurrence.

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Stage IV Colorectal Cancer: Lina's Patient Story

Patient Info: Lina | Stage IV

Lina was living with Stage IV colorectal cancer 2–3 years after diagnosis after stopping chemotherapy, radiation, and immunotherapy.

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Stage II Colorectal Cancer: Lina's Survivor Story

Patient Info: Lina | Stage II

Some years after her Stage II colorectal cancer diagnosis, Lina said she was cancer-free.

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Budesonide resolved severe capecitabine-related diarrhoea during rectal cancer treatment

Patient Info: Anonymized, Female, 70+ | Stage II

The treatment-resistant diarrhoea resolved within two weeks of starting budesonide, and follow-up endoscopy and biopsies showed complete resolution of the bowel inflammation.

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Pemphigus Vulgaris After Rectal Cancer Surgery and Ileostomy

Patient Info: Anonymized, Female, 50s | Stage Metastatic/Advanced

Clinicians found no evidence of residual internal malignancy during evaluation of her skin disease, and the pemphigus lesions healed after rituximab with remission maintained for 14 months.

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Stage III Colorectal Cancer: Mike's Patient Story

Patient Info: Mike Fitzpatrick, Male, 40s | Stage III

Mike entered remission after treatment and returned to public service. He died on January 6, 2020.

Stage III Colorectal Cancer: Suzanne's Patient Story

Patient Info: Suzanne Kulliver, Female | Stage III

Suzanne completed colon cancer treatment in November 2015 and later reported feeling well and returning to an active routine.

Severe lung injury during panitumumab treatment for metastatic colon cancer

Patient Info: Anonymized, Female, 50s | Stage IV

Metastatic Site: lungs, bones, pelvis

She died from respiratory failure 13 days after the onset of pulmonary symptoms. Autopsy showed diffuse alveolar damage consistent with acute respiratory distress syndrome and metastatic colon adenocarcinoma in the right lung.

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Metastatic Colon Cancer With KRAS, NRAS, and BRAF Mutations

Patient Info: Anonymized, Male, 60s | Stage IV

Biomarkers: KRAS exon 3 ; NRAS exon 2 ; BRAF exon 10 ; PIK3CA exon 2 .

Metastatic Site: liver

The liver metastases progressed despite FOLFOX and bevacizumab, and he died within one year of the initial diagnosis.

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Metastatic Rectal Cancer Complicated by Salmonella-Related Bowel Perforation

Patient Info: Anonymized, Male, 60s | Stage IV

Metastatic Site: liver; lungs

Postoperative infection and wound complications delayed palliative chemotherapy, and he died from metastatic rectal cancer one year later.

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Long-term survival after surgery for colon cancer with a stomach metastasis

Patient Info: Anonymized, Female, 60s | Stage IV

Metastatic Site: stomach

She had no signs of recurrence 7 years and 4 months after surgery and was living with good quality of life.

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Severe Kidney Injury During Oxaliplatin Treatment for Metastatic Colorectal Cancer

Patient Info: Anonymized, male, 60s | Stage IV

Metastatic Site: liver

His kidney function returned to baseline 2 months after the acute injury, and colorectal cancer treatment continued with 5-FU and leucovorin after oxaliplatin was stopped.

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Colon Cancer and a Separate Liposarcoma Recurring at the Same Time

Patient Info: Anonymized, Male, 60s | Stage Metastatic/Advanced

Metastatic Site: liver|pelvic lymph node

Follow-up imaging showed no evidence of colon cancer after FOLFIRI produced a complete response in the liver and pelvic lymph node. He remained without evidence of disease 1.7 years after recurrence.

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Rectal Signet Ring Cell Cancer With Rapid, Unusual Metastatic Spread

Patient Info: Anonymized, Male, Under 40 | Stage Metastatic/Advanced

Metastatic Site: peritoneum|lumbosacral vertebrae|bone marrow|right…

The cancer recurred 3 months after surgery and spread rapidly to the peritoneum, bones, bone marrow, orbit, and skin. He later entered palliative care.

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Oxaliplatin-Related Muscle Breakdown During Colorectal Cancer Treatment

Patient Info: Anonymized, Male, 50s | Stage III

Biomarkers: CEA 1.01 ng/mL; CA 19-9 <0.6 U/mL

He recovered fully from rhabdomyolysis, completed adjuvant capecitabine, and entered follow-up without evidence of cancer recurrence.

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Metastatic Colorectal Cancer Treatment Complicated by Severe Lung Inflammation

Patient Info: Anonymized, Male, 70+ | Stage IV

Biomarkers: KRAS wild type; NRAS wild type

Metastatic Site: liver

He recovered from the severe treatment-related lung inflammation, was weaned off oxygen within 1 month, and continued oncology follow-up while living with Stage IV colorectal cancer.

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Rectal Cancer Spread to the Optic Nerve and Caused Vision Loss

Patient Info: Anonymized, Male, 40s | Stage Metastatic/Advanced

Biomarkers: BRAF mutant; KRAS wild type

Metastatic Site: lungs|liver|left optic nerve

He had a high burden of metastatic rectal cancer involving the lungs, liver, and left optic nerve. He died about 4 months after presenting with vision loss.

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Rectal Cancer With a Solitary Metastasis in the Thigh

Patient Info: Anonymized, Male, 40s | Stage Metastatic/Advanced

Metastatic Site: right proximal thigh skeletal muscle

A biopsy-confirmed right proximal thigh metastasis remained after chemotherapy. PET/CT found no other active metastatic site, and further surgery plus chemotherapy was planned.

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